Fibrate Drugs Market Report 2025

The fibrate drugs market size has grown steadily in recent years. It will grow from $3.49 billion in 2024 to $3.62 billion in 2025 at a compound annual growth rate (CAGR) of 3.8%. The growth in the historic period can be attributed to emergence of lipid management, cholesterol management focus, clinical research and trials, cardiovascular risk reduction, combination therapies.

The fibrate drugs market size is expected to see strong growth in the next few years. It will grow to $4.81 billion in 2029 at a compound annual growth rate (CAGR) of 7.4%. The growth in the forecast period can be attributed to evolving treatment guidelines, focus on residual risk, precision medicine advancements, innovation in drug delivery. Major trends in the forecast period include alternative formulations, telemedicine integration, fibrates in high-risk groups, targeting triglyceride levels, focus on hdl raising.

The anticipated rise in the incidence of cardiac diseases is poised to fuel the growth of the fibrate drug market in the future. Cardiac diseases encompass a spectrum of conditions affecting the heart and blood vessels, including coronary heart disease, congenital heart disease, and others. Fibrates serve as a treatment to prevent further heart attacks and strokes in individuals already affected by circulatory system conditions, thereby contributing to the expansion of the fibrate drug market. As of May 2023, according to the Centers for Disease Control and Prevention Highlights, coronary heart disease was estimated to be responsible for 375,476 deaths in 2021. Additionally, data published by the New York government in December 2022 revealed that heart disease claims the lives of approximately 697,000 people annually in the United States, accounting for 1 in every 5 fatalities. This includes around 805,000 Americans experiencing a heart attack each year, with 605,000 being first-time occurrences and 200,000 resulting from previous heart attacks. Consequently, the increased incidence of cardiac diseases is a significant driver for the growth of the fibrate drug market.

Government initiatives targeting cardiovascular diseases are expected to make a substantial contribution to the growth of the fibrate drugs market in the future. These initiatives typically involve public health campaigns aimed at increasing awareness about cardiovascular diseases, their risk factors, and preventive measures. Consequently, more individuals may receive diagnoses for conditions such as hyperlipidemia (elevated lipid levels in the blood), for which fibrates are commonly prescribed. As an illustration, in October 2023, the government of Australia allocated $220 million to the Cardiovascular Health Mission. This initiative brings together researchers, health professionals, industry stakeholders, and patients to make transformative improvements in heart and vascular health, as well as stroke prevention and treatment for all Australians. Hence, the growing government initiatives focused on cardiovascular diseases are poised to propel the fibrate drugs market.

Product innovations are becoming increasingly prominent in the fibrate drugs market. Leading companies in this sector are concentrating on developing new solutions to maintain their competitive edge. For example, in October 2022, United Therapeutics, a US-based firm dedicated to creating innovative therapies for rare diseases, announced the top-line data from the EXPEDITE Study concerning the induction of Remodulin prior to Orenitram therapy. The findings revealed that initiating treatment with Remodulin before starting Orenitram led to quicker attainment of therapeutic doses in patients with pulmonary arterial hypertension. This method also enhanced tolerability and minimized side effects, suggesting that the combination represents a more effective treatment strategy.

Major players in the fibrate drugs market are directing their efforts toward the integration of digital health solutions tailored for cardiovascular diseases. The trend involves healthcare providers increasingly prescribing combinations of fibrates with other lipid-lowering agents, such as statins, to achieve synergistic effects and address multiple aspects of dyslipidemia. An instance of this is seen in August 2023 when GE Healthcare, a US-based manufacturing company, launched CardioVisio for Atrial Fibrillation (AFib), a digital tool designed to assist clinicians in visualizing longitudinal data relevant to disease progression from various sources. This tool aims to drive evidence-based clinical decision support guided by current AFib guidelines.

In February 2023, AstraZeneca PLC, a UK-based pharmaceuticals company, acquired CinCor Pharma Inc for an undisclosed amount. This strategic acquisition is intended to strengthen AstraZeneca's cardiorenal pipeline by adding baxdrostat, a novel aldosterone synthase inhibitor under development for lowering blood pressure. Baxdrostat, a candidate medication from CinCor, aligns with AstraZeneca's mission to advance the treatment of cardiorenal illnesses. Elevated aldosterone levels are associated with hypertension and various cardiorenal conditions, including coronary artery disease and chronic kidney disease. CinCor Pharma Inc., based in the US, specializes in the development of fibrate drugs.

Major companies operating in the fibrate drugs market include Pfizer Inc., F. Hoffmann-La Roche AG, Merck & Co Inc., AbbVie Inc., Bayer AG, Novartis AG, Sanofi SA, Kowa Company Ltd., Bristol-Myers Squibb Co, Abbott Laboratories, AstraZeneca plc, GlaxoSmithKline Plc, Takeda Pharmaceutical Company, Boehringer Ingelheim International GmbH, Teva Pharmaceutical Industries Ltd., Mylan N.V., Daiichi Sankyo Co Ltd., Macleods Pharmaceuticals Ltd., Sun Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Aurobindo Pharma Limited, Cipla Inc., Zydus Lifesciences Ltd, Lupin Limited, Glenmark Pharmaceuticals, Torrent Pharmaceuticals Ltd., Natco Pharma, Hetero Drugs Ltd.

North America was the largest region in the fibrate drugs market in 2024. The regions covered in the fibrate drugs market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the fibrate drugs market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Fibrate drugs are prescribed medications designed to lower triglyceride levels and elevate high-density lipoprotein (HDL) cholesterol levels. They are commonly employed for the treatment of hypercholesterolemia or mixed dyslipidemia.

The primary categories of fibrate drugs encompass clofibrate, fenofibrates, fenofibric acids, gemfibrozil, and others. Clofibrate, identified as a fibric acid derivative, is employed for the management of hypertriglyceridemia and elevated cholesterol levels. Its primary function is to regulate and control increased levels of cholesterol and triglycerides. Fibrate drugs are utilized in the treatment of conditions such as hypercholesterolemia and heart attacks, and they are available at hospital pharmacies, online pharmacies, and retail pharmacies. End-users of fibrate drugs include hospitals, homecare, specialty clinics, and others.

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The fibrate drugs market consists of sales of medicines for high cholesterol, hyperlipoproteinemia, and hypertriglyceridemia. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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