Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient's health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host's system is altered by vaccine administration. Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy. Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.
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Table of Contents
1. Personalized Vaccinology 2. Vaccine Adjuvants and their role in modulating immune signaling pathways 3. Technologies to measure vaccine immune response against infectious diseases 4. Vaccines for Cancer 5. Vaccines for Autoimmune Diseases 6. Vaccines for Allergy 7. Virus vaccine production using cell-based technology 8. Dendritic cell-based cancer vaccine production
Authors
Mahbuba Rahman McMaster University, Hamilton, Ontario, Canada.Dr. Mahbuba Rahman earned her B.Sc. (Honors), M.Sc in Microbiology and an M.S. in Environmental Science. She completed her PhD in Metabolic Engineering from the Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Japan. Post Ph.D., she worked with a transgenic mice model of Smith-Lemli-Opitz syndrome, which is an inborn error of cholesterol synthesis, at Children's Hospital Research Institute (CHORI), Oakland, California. Mahbuba has published several research articles including clinical and non-clinical research in high-impact factor journals. She also authored multiple review articles and book chapters in high-impact journals and with well-known publishers. She is also an editor of an eBook on cancer immunotherapy and an editor of a hard copy book on Metabolomics A Path Towards Personalized Medicine. She is also a special topic editor and guest editor in Frontiers in Genetics, Frontiers in Immunology, and in Journal of Microbiological Methods. At present, she is an Adjunct Assistant Professor at the Department of Biology, at McMaster University. She is investigating the role of global regulators in pathogenic and non-pathogenic microorganisms using systems biology approaches.
