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Liquid Biopsy Market Report and Forecast 2024-2032

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    Report

  • 160 Pages
  • February 2024
  • Region: Global
  • Expert Market Research
  • ID: 5941079

Global Liquid Biopsy Market Outlook

The global liquid biopsy market size was valued at USD 3.5 billion in 2023, driven by increase prevalence of cancer across the globe. The market size is anticipated to grow at a CAGR of 15.3% during the forecast period of 2024-2032 to achieve a value of USD 12.8 billion by 2032.

Liquid Biopsy: Introduction

A liquid biopsy is a minimally invasive medical test that detects cancer-related biomarkers in bodily fluids like blood. It offers a real-time, comprehensive snapshot of a tumor's genetic landscape without the need for traditional, more invasive tissue biopsies. Widely praised for its potential to transform cancer diagnosis, monitoring, and personalized treatment, liquid biopsy stands at the forefront of precision oncology, enabling early detection and dynamic tracking of cancer's evolution and treatment response.

Key Trends in the Global Liquid Biopsy Market

The global liquid biopsy market is witnessing significant growth, propelled by advancements in non-invasive cancer diagnostics and precision medicine. Enhanced sequencing technologies offer deeper insights into genetic mutations and other alterations in DNA, facilitating early detection and personalized treatment strategies. Rapid advances in detecting and analyzing ctDNA are improving the sensitivity and specificity of liquid biopsies, aiding in cancer monitoring and treatment adjustment.

Liquid biopsies are increasingly being used for early cancer detection and screening, especially in high-risk individuals, due to their non-invasive nature and high accuracy. The ability to frequently monitor the genetic evolution of tumors helps in understanding treatment effectiveness and detecting resistance mechanisms early.

Liquid biopsies provide valuable information on tumor genetics, enabling healthcare professionals to tailor treatment plans based on individual molecular tumor profiles. They are instrumental in detecting minimal residual disease, offering a more precise evaluation of treatment success and early detection of relapse.

AI and machine learning are being integrated to analyze complex data from liquid biopsies, enhancing diagnostic accuracy and predictive capabilities. Advanced algorithms can identify patterns associated with early-stage cancers, potentially revolutionizing cancer screening and diagnosis.

While cancer remains the primary focus, the potential of liquid biopsies is being explored in other areas such as prenatal screening, cardiovascular diseases, and transplant medicine. Liquid biopsies are a valuable tool for biomarker discovery, aiding in the understanding of disease mechanisms and the development of new therapeutic targets.

Partnerships between biotechnology firms and academic institutions are driving innovation and research in the field. Companies are forming alliances to combine expertise, expand market presence, and accelerate the development and commercialization of new liquid biopsy tests.

Global Liquid Biopsy Market Segmentation

Market Breakup by Sample

  • Blood Sample
  • Others

Market Breakup by Biomarker

  • Circulating Tumor Cells (CTCs)
  • Circulating Nucleic Acids
  • Exosomes/ Microvesicles
  • Circulating Proteins

Market Breakup by Technology

  • Multi-gene-parallel Analysis (NGS)
  • Single Gene Analysis (PCR Microarrays)

Market Breakup by Application

  • Cancer
  • Reproductive Health
  • Organ Transplantation
  • Infectious Diseases Testing
  • Others

Market Breakup by End-user

  • Hospitals and Laboratories
  • Specialty Clinics
  • Academic and Research Centers
  • Others

Market Breakup by Clinical Application

  • Therapy Selection
  • Treatment Monitoring
  • Early Cancer Screening
  • Recurrence Monitoring
  • Others

Market Breakup by Product

  • Instruments
  • Consumables Kits and Reagents
  • Software and Services

Market Breakup by Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

Global Liquid Biopsy Market Overview

The United States and Canada are at the forefront in adopting liquid biopsy tests, driven by strong healthcare infrastructure, high patient awareness, and substantial investments in research and development.

The presence of leading biotechnology and diagnostic companies, coupled with favorable reimbursement policies and a high incidence of cancer, fuels the market's growth. There is also a strong emphasis on precision medicine and personalized healthcare.

European regions show a high adoption rate of liquid biopsy tests, supported by well-established healthcare systems and strong government support for cancer research. The market is growing, with increasing awareness and improving healthcare infrastructure, although it may be more price-sensitive compared to Western Europe. Stringent regulatory standards and a focus on research and innovation are significant. There's also a growing emphasis on non-invasive diagnostic methods and cancer screening programs.

In Asia-Pacific, developed nations (Japan, Australia, South Korea) have advanced healthcare systems and show significant growth in the liquid biopsy market, driven by technological advancements and increasing healthcare expenditure. There's a high focus on cancer research and increasing investment from both public and private sectors. The large population base also presents a significant opportunity for market expansion.

Global Liquid Biopsy Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
  • ANGLE plc
  • Oncimmune Holdings PLC
  • Guardant Health
  • Myriad Genetics, Inc.
  • Biocept, Inc.
  • Lucence Health Inc.
  • Freenome Holdings, Inc.
  • F.Hoffmann La Roche Ltd.
  • QIAGEN
  • Illumina, Inc.
  • Thermo Fisher Scientific, Inc.
  • Exact Sciences Corporation
  • Bio-Rad Laboratories, Inc.
  • Menarini Silicon Biosystems S.p.A.
  • Epigenomics AG


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Table of Contents

1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage - Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global Liquid Biopsy Market Overview
3.1 Global Liquid Biopsy Market Historical Value (2017-2023)
3.2 Global Liquid Biopsy Market Forecast Value (2024-2032)
4 Global Liquid Biopsy Market Landscape
4.1 Global Liquid Biopsy Developers Landscape
4.1.1 Analysis by Year of Establishment
4.1.2 Analysis by Company Size
4.1.3 Analysis by Region
4.2 Global Liquid Biopsy Product Landscape
4.2.1 Analysis by Sample
4.2.2 Analysis by Biomarker
4.2.3 Analysis by Technology
4.2.4 Analysis by Application
4.2.5 Analysis by End-use
4.2.6 Analysis by Clinical Application
4.2.7 Analysis by Product
5 Global Liquid Biopsy Market Dynamics
5.1 Market Drivers and Constraints
5.2 SWOT Analysis
5.3 Porter’s Five Forces Model
5.4 Key Demand Indicators
5.5 Key Price Indicators
5.6 Industry Events, Initiatives, and Trends
5.7 Value Chain Analysis
6 Global Liquid Biopsy Market Segmentation
6.1 Global Liquid Biopsy Market by Sample
6.1.1 Market Overview
6.1.2 Blood Sample
6.1.3 Others
6.2 Global Liquid Biopsy Market by Biomarker
6.2.1 Market Overview
6.2.2 Circulating Tumor Cells (CTCs)
6.2.3 Circulating Nucleic Acids
6.2.4 Exosomes/ Microvesicles
6.2.5 Circulating Proteins
6.3 Global Liquid Biopsy Market by Technology
6.3.1 Market Overview
6.3.2 Multi-gene-parallel Analysis (NGS)
6.3.3 Single Gene Analysis (PCR Microarrays)
6.4 Global Liquid Biopsy Market by Application
6.4.1 Market Overview
6.4.2 Cancer
6.4.3 Reproductive Health
6.4.4 Organ Transplantation
6.4.5 Infectious Diseases Testing
6.4.6 Others
6.5 Global Liquid Biopsy Market by End-use
6.5.1 Market Overview
6.5.2 Hospitals and Laboratories
6.5.3 Specialty Clinics
6.5.4 Academic and Research Centers
6.5.5 Others
6.6 Global Liquid Biopsy Market by Clinical Application
6.6.1 Market Overview
6.6.2 Therapy Selection
6.6.3 Treatment Monitoring
6.6.4 Early Cancer Screening
6.6.5 Recurrence Monitoring
6.6.6 Others
6.7 Global Liquid Biopsy Market by Product
6.7.1 Market Overview
6.7.2 Instruments
6.7.3 Consumables Kits and Reagents
6.7.4 Software and Services
6.8 Global Liquid Biopsy Market by Region
6.8.1 Market Overview
6.8.2 North America
6.8.3 Europe
6.8.4 Asia Pacific
6.8.5 Latin America
6.8.6 Middle East and Africa
7 North America Liquid Biopsy Market
7.1 Market Share by Country
7.2 United States of America
7.3 Canada
8 Europe Liquid Biopsy Market
8.1 Market Share by Country
8.2 United Kingdom
8.3 Germany
8.4 France
8.5 Italy
8.6 Others
9 Asia Pacific Liquid Biopsy Market
9.1 Market Share by Country
9.2 China
9.3 Japan
9.4 India
9.5 ASEAN
9.6 Others
10 Latin America Liquid Biopsy Market
10.1 Market Share by Country
10.2 Brazil
10.3 Argentina
10.4 Mexico
10.5 Others
11 Middle East and Africa Liquid Biopsy Market
11.1 Market Share by Country
11.2 Saudi Arabia
11.3 United Arab Emirates
11.4 Nigeria
11.5 South Africa
11.6 Others
12 Patent Analysis
12.1 Analysis by Type of Patent
12.2 Analysis by Publication year
12.3 Analysis by Issuing Authority
12.4 Analysis by Patent Age
12.5 Analysis by CPC Analysis
12.6 Analysis by Patent Valuation
12.7 Analysis by Key Players
13 Grants Analysis
13.1 Analysis by Year
13.2 Analysis by Amount Awarded
13.3 Analysis by Issuing Authority
13.4 Analysis by Grant Application
13.5 Analysis by Funding Institute
13.6 Analysis by NIH Departments
13.7 Analysis by Recipient Organization
14 Funding and Investment Analysis
14.1 Analysis by Funding Instances
14.2 Analysis by Type of Funding
14.3 Analysis by Funding Amount
14.4 Analysis by Leading Players
14.5 Analysis by Leading Investors
14.6 Analysis by Geography
15 Partnership and Collaborations Analysis
15.1 Analysis by Partnership Instances
15.2 Analysis by Type of Partnership
15.3 Analysis by Leading Players
15.4 Analysis by Geography
16 Regulatory Framework
16.1 Regulatory Overview
16.2 US FDA
16.3 EU EMA
16.4 INDIA CDSCO
16.5 JAPAN PMDA
16.6 Others
17 Supplier Landscape
17.1 ANGLE plc
17.1.1 Financial Analysis
17.1.2 Product Portfolio
17.1.3 Demographic Reach and Achievements
17.1.4 Mergers and Acquisitions
17.1.5 Certifications
17.2 Oncimmune Holdings PLC
17.2.1 Financial Analysis
17.2.2 Product Portfolio
17.2.3 Demographic Reach and Achievements
17.2.4 Mergers and Acquisitions
17.2.5 Certifications
17.3 Guardant Health
17.3.1 Financial Analysis
17.3.2 Product Portfolio
17.3.3 Demographic Reach and Achievements
17.3.4 Mergers and Acquisitions
17.3.5 Certifications
17.4 Myriad Genetics, Inc.
17.4.1 Financial Analysis
17.4.2 Product Portfolio
17.4.3 Demographic Reach and Achievements
17.4.4 Mergers and Acquisitions
17.4.5 Certifications
17.5 Biocept, Inc.
17.5.1 Financial Analysis
17.5.2 Product Portfolio
17.5.3 Demographic Reach and Achievements
17.5.4 Mergers and Acquisitions
17.5.5 Certifications
17.6 Lucence Health Inc.
17.6.1 Financial Analysis
17.6.2 Product Portfolio
17.6.3 Demographic Reach and Achievements
17.6.4 Mergers and Acquisitions
17.6.5 Certifications
17.7 Freenome Holdings, Inc.
17.7.1 Financial Analysis
17.7.2 Product Portfolio
17.7.3 Demographic Reach and Achievements
17.7.4 Mergers and Acquisitions
17.7.5 Certifications
17.8 F.Hoffmann La Roche Ltd.
17.8.1 Financial Analysis
17.8.2 Product Portfolio
17.8.3 Demographic Reach and Achievements
17.8.4 Mergers and Acquisitions
17.8.5 Certifications
17.9 QIAGEN
17.9.1 Financial Analysis
17.9.2 Product Portfolio
17.9.3 Demographic Reach and Achievements
17.9.4 Mergers and Acquisitions
17.9.5 Certifications
17.10 Illumina, Inc.
17.10.1 Financial Analysis
17.10.2 Product Portfolio
17.10.3 Demographic Reach and Achievements
17.10.4 Mergers and Acquisitions
17.10.5 Certifications
17.11 Thermo Fisher Scientific, Inc.
17.11.1 Financial Analysis
17.11.2 Product Portfolio
17.11.3 Demographic Reach and Achievements
17.11.4 Mergers and Acquisitions
17.11.5 Certifications
17.12 Exact Sciences Corporation
17.12.1 Financial Analysis
17.12.2 Product Portfolio
17.12.3 Demographic Reach and Achievements
17.12.4 Mergers and Acquisitions
17.12.5 Certifications
17.13 Bio-Rad Laboratories, Inc.
17.13.1 Financial Analysis
17.13.2 Product Portfolio
17.13.3 Demographic Reach and Achievements
17.13.4 Mergers and Acquisitions
17.13.5 Certifications
17.14 Menarini Silicon Biosystems S.p.A.
17.14.1 Financial Analysis
17.14.2 Product Portfolio
17.14.3 Demographic Reach and Achievements
17.14.4 Mergers and Acquisitions
17.14.5 Certifications
17.15 Epigenomics AG
17.15.1 Financial Analysis
17.15.2 Product Portfolio
17.15.3 Demographic Reach and Achievements
17.15.4 Mergers and Acquisitions
17.15.5 Certifications
18 Global Liquid Biopsy Market - Distribution Model (Additional Insight)
18.1 Overview
18.2 Potential Distributors
18.3 Key Parameters for Distribution Partner Assessment
19 Key Opinion Leaders (KOL) Insights (Additional Insight)
20 Company Competitiveness Analysis (Additional Insight)
20.1 Very Small Companies
20.2 Small Companies
20.3 Mid-Sized Companies
20.4 Large Companies
20.5 Very Large Companies
21 Payment Methods (Additional Insight)
21.1 Government Funded
21.2 Private Insurance
21.3 Out-of-Pocket
*Additional insights provided are customisable as per client requirements.

Companies Mentioned

  • ANGLE plc
  • Oncimmune Holdings PLC
  • Guardant Health
  • Myriad Genetics Inc.
  • Biocept Inc.
  • Lucence Health Inc.
  • Freenome Holdings Inc.
  • F.Hoffmann La Roche Ltd.
  • QIAGEN
  • Illumina Inc.
  • Thermo Fisher Scientific Inc.
  • Exact Sciences Corporation
  • Bio-Rad Laboratories Inc.
  • Menarini Silicon Biosystems S.p.A.
  • Epigenomics AG

Methodology

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Table Information