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Cystinuria Market Report and Forecast 2024-2032

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    Report

  • 180 Pages
  • February 2024
  • Region: Global
  • Expert Market Research
  • ID: 5941110

Cystinuria Market Outlook

The cystinuria market size was valued at USD 106.45 million in 2023, driven by the increasing research to develop more effective and less invasive treatments for cystinuria in the major markets. The market size is anticipated to grow at a CAGR of 4.5% during the forecast period of 2024-2032 to achieve a value of USD 157.67 million by 2032.

Cystinuria: Introduction

Cystinuria is a rare genetic disorder characterized by the excessive excretion of cystine, an amino acid, in the urine. This condition leads to the formation of cystine stones in the kidneys, bladder, or urinary tract. Symptoms include recurrent kidney stones, pain, and urinary tract infections. Cystinuria is caused by mutations in the genes responsible for transporting cystine in the kidneys. Management involves staying well-hydrated, dietary adjustments, and medications to reduce stone formation and relieve symptoms.

Key Trends in the Cystinuria Market

There's ongoing research to develop more effective and less invasive treatments for cystinuria. This includes novel medications aimed at reducing cystine levels in the urine and improving the solubility of cystine to prevent stone formation. Additionally, advancements in minimally invasive surgical techniques for stone removal are improving patient outcomes.

As cystinuria is a genetic disorder, there's a trend towards utilizing genetic testing to confirm diagnoses and inform treatment decisions. This approach facilitates personalized treatment plans, optimizing dietary and medication regimens based on individual genetic profiles and disease severity.

Increasing emphasis is being placed on patient education and the provision of dietary management tools. These resources aim to help individuals with cystinuria make informed dietary choices to minimize stone formation, enhancing the effectiveness of medical treatments.

The development of home monitoring solutions for urinary cystine levels allows for more frequent and convenient patient monitoring, aiding in timely treatment adjustments and better disease management.

Collaboration between research institutions, healthcare providers, and patient advocacy groups is fostering a comprehensive approach to understanding cystinuria and developing new treatments. These partnerships are crucial for driving research, raising awareness, and improving patient care and support.

Cystinuria Market Segmentation

Market Breakup by Disease Type

  • Type I cystinuria
  • Type II cystinuria
  • Type III cystinuria

Market Breakup by Drug Type

  • Tiopronin
  • Penicillamine
  • Others

Market Breakup by Dosage Form

  • Solutions
  • Tablet
  • Injection
  • Others

Market Breakup by Route of Administration

  • Oral
  • Intravenous
  • Topical
  • Others

Market Breakup by Distribution Channel

  • Hospital Pharmacy
  • Online Pharmacy
  • Retail Pharmacy

Market Breakup by - 8MM

  • United States
  • EU-4 and the United Kingdom
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Japan
  • China

Cystinuria Market Overview

In North America, the cystinuria market is shaped by advanced healthcare infrastructure and a high awareness of rare diseases. The region benefits from strong patient support networks and advocacy groups that promote research and access to care. There's a focus on genetic testing and personalized medicine to manage cystinuria effectively. Treatment approaches include nutritional guidance, medication, and, in some cases, surgical interventions. The U.S. and Canada also have specialized centers offering comprehensive care for patients with cystinuria.

Europe's market is characterized by well-established healthcare systems and a strong focus on rare disease research and treatment. The European Union's policies on rare diseases encourage collaboration across member states, facilitating research, treatment development, and patient mobility for specialized care. There's an emphasis on early diagnosis through genetic screening and a multidisciplinary approach to treatment, including dietary management, pharmacotherapy, and advanced techniques for stone removal and prevention.

Japan's market for cystinuria is supported by a high standard of healthcare and a strong emphasis on innovation and precision medicine. The country has specific programs and policies in place to address rare diseases, providing support for research, development of new treatments, and patient care. Treatment approaches are comprehensive, focusing on dietary management, medication, and advanced technologies for stone detection and treatment. Patient awareness and education about cystinuria are also key components of the healthcare approach in Japan.

Cystinuria Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players.
  • Retrophin
  • Recordati Rare Diseases
  • Mission Therapeutics
  • Enterome Bioscience
  • Horizon Therapeutics
  • Arcturus Therapeutics
  • Codexis
  • Mito pharmaceuticals
  • Abbott
  • Bausch Health Companies
  • Allena Pharmaceuticals
  • Mylan N.V. (now part of Viatris)
  • Chiesi Farmaceutici S.p.A


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Table of Contents

1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage - Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Cystinuria Overview
3.1 Guidelines and Stages
3.2 Pathophysiology
3.3 Screening and Diagnosis
3.4 Pathway
4 Patient Profile
4.1 Patient Profile Overview
4.2 Patient Psychology and Emotional Impact Factors
4.3 Risk Assessment and Success Rate
5 Cystinuria Epidemiology Analysis- 8 Major Markets
5.1 8MM Epidemiology Scenario Overview (2017-2032)
5.2 United States Cystinuria Epidemiology Forecast (2017-2032)
5.3 EU-4 and United Kingdom Cystinuria Epidemiology Forecast (2017-2032)
5.3.1 Germany Cystinuria Epidemiology Forecast (2017-2032)
5.3.2 France Cystinuria Epidemiology Forecast (2017-2032)
5.3.3 Italy Cystinuria Epidemiology Forecast (2017-2032)
5.3.4 Spain Cystinuria Epidemiology Forecast (2017-2032)
5.3.5 United Kingdom Cystinuria Epidemiology Forecast (2017-2032)
5.4 Japan Cystinuria Epidemiology Forecast (2017-2032)
5.5 China Cystinuria Epidemiology Forecast (2017-2032)
6 Cystinuria Market Overview - 8 Major Markets
6.1 Cystinuria Market Historical Value (2017-2023)
6.2 Cystinuria Market Forecast Value (2024-2032)
7 Cystinuria Market Landscape - 8 Major Markets
7.1 Cystinuria Market: Developers Landscape
7.1.1 Analysis by Year of Establishment
7.1.2 Analysis by Company Size
7.1.3 Analysis by Region
7.2 Cystinuria Market: Product Landscape
7.2.1 Analysis by Drug Class
7.2.2 Analysis by Route of Administration
8 Cystinuria Challenges and Unmet Needs
8.1 Pathway Challenges
8.2 Compliance and Drop-Out Analysis
8.3 Awareness and Prevention Gaps
9 Cost of Treatment
10 Cystinuria Market Dynamics
10.1 Market Drivers and Constraints
10.2 SWOT Analysis
10.3 Porter’s Five Forces Model
10.4 Key Demand Indicators
10.5 Key Price Indicators
10.6 Industry Events, Initiatives, and Trends
10.7 Value Chain Analysis
11 Cystinuria Market Segmentation - 8 Major Markets
11.1 Cystinuria Market by Disease Type
11.1.1 Market Overview
11.1.2 Type I Cystinuria
11.1.3 Type II Cystinuria
11.1.4 Type III Cystinuria
11.2 Cystinuria Market by Drug Type
11.2.1 Market Overview
11.2.2 Tiopronin
11.2.3 Penicillamine
11.2.4 Others
11.3 Cystinuria Market by Dosage Form
11.3.1 Market Overview
11.3.2 Solutions
11.3.3 Tablet
11.3.4 Injection
11.3.5 Others
11.4 Cystinuria Market by Route of Administration
11.4.1 Market Overview
11.4.2 Oral
11.4.3 Intravenous
11.4.4 Topical
11.4.5 Others
11.5 Cystinuria Market by Distribution Channel
11.5.1 Market Overview
11.5.2 Hospital Pharmacy
11.5.3 Online Pharmacy
11.5.4 Retail Pharmacy
11.6 Cystinuria Market by Region
11.6.1 Market Overview
11.6.2 United States
11.6.3 EU-4 and the United Kingdom
11.6.3.1 Germany
11.6.3.2 France
11.6.3.3 Italy
11.6.3.4 Spain
11.6.3.5 United Kingdom
11.6.4 Japan
11.6.5 China
12 United States Cystinuria Market
12.1 United States Cystinuria Market Historical Size (2017-2023)
12.2 United States Cystinuria Market Forecast Size (2024-2032)
12.3 United States Cystinuria Market by Disease Type
12.3.1 Market Overview
12.3.2 Type I Cystinuria
12.3.3 Type II Cystinuria
12.3.4 Type III Cystinuria
12.4 United States Cystinuria Market by Drug Type
12.4.1 Market Overview
12.4.2 Tiopronin
12.4.3 Penicillamine
12.4.4 Others
13 EU-4 and United Kingdom Cystinuria Market
13.1 EU-4 and United Kingdom Cystinuria Market Historical Value (2017-2023)
13.2 EU-4 and United Kingdom Cystinuria Market Forecast Value (2024-2032)
13.3 EU-4 and United Kingdom Cystinuria Market by Disease Type
13.3.1 Market Overview
13.3.2 Type I Cystinuria
13.3.3 Type II Cystinuria
13.3.4 Type III Cystinuria
13.4 EU-4 and United Kingdom Cystinuria Market by Drug Type
13.4.1 Market Overview
13.4.2 Tiopronin
13.4.3 Penicillamine
13.4.4 Others
14 Japan Cystinuria Market
14.1 Japan Cystinuria Market Historical Size (2017-2023)
14.2 Japan Cystinuria Market Forecast Size (2024-2032)
14.3 Japan Cystinuria Market by Disease Type
14.3.1 Market Overview
14.3.2 Type I Cystinuria
14.3.3 Type II Cystinuria
14.3.4 Type III Cystinuria
14.4 Japan Cystinuria Market by Drug Type
14.4.1 Market Overview
14.4.2 Tiopronin
14.4.3 Penicillamine
14.4.4 Others
15 China Cystinuria Market
15.1 China Cystinuria Market Historical Size (2017-2023)
15.2 China Cystinuria Market Forecast Size (2024-2032)
15.3 China Cystinuria Market by Disease Type
15.3.1 Market Overview
15.3.2 Type I Cystinuria
15.3.3 Type II Cystinuria
15.3.4 Type III Cystinuria
15.4 China Cystinuria Market by Drug Type
15.4.1 Market Overview
15.4.2 Tiopronin
15.4.3 Penicillamine
15.4.4 Others
16 Regulatory Framework
16.1 Regulatory Overview
16.1.1 US FDA
16.1.2 EU EMA
16.1.3 Japan PMDA
16.1.4 Others
17 Patent Analysis
17.1 Analysis by Type of Patent
17.2 Analysis by Publication year
17.3 Analysis by Issuing Authority
17.4 Analysis by Patent Age
17.5 Analysis by CPC Analysis
17.6 Analysis by Patent Valuation
17.7 Analysis by Key Players
18 Grants Analysis
18.1 Analysis by Year
18.2 Analysis by Amount Awarded
18.3 Analysis by Issuing Authority
18.4 Analysis by Grant Application
18.5 Analysis by Funding Institute
18.6 Analysis by NIH Departments
18.7 Analysis by Recipient Organization
19 Clinical Trials Analysis
19.1 Analysis by Trial Registration Year
19.2 Analysis by Trial Status
19.3 Analysis by Trial Phase
19.4 Analysis by Therapeutic Area
19.5 Analysis by Geography
20 Funding and Investment Analysis
20.1 Analysis by Funding Instances
20.2 Analysis by Type of Funding
20.3 Analysis by Funding Amount
20.4 Analysis by Leading Players
20.5 Analysis by Leading Investors
20.6 Analysis by Geography
21 Partnership and Collaborations Analysis
21.1 Analysis by Partnership Instances
21.2 Analysis by Type of Partnership
21.3 Analysis by Leading Players
21.4 Analysis by Geography
22 Supplier Landscape
22.1 Retrophin
22.1.1 Financial Analysis
22.1.2 Product Portfolio
22.1.3 Demographic Reach and Achievements
22.1.4 Mergers and Acquisitions
22.1.5 Certifications
22.2 Recordati Rare Diseases Inc.
22.2.1 Financial Analysis
22.2.2 Product Portfolio
22.2.3 Demographic Reach and Achievements
22.2.4 Mergers and Acquisitions
22.2.5 Certifications
22.3 Mission Therapeutics
22.3.1 Financial Analysis
22.3.2 Product Portfolio
22.3.3 Demographic Reach and Achievements
22.3.4 Mergers and Acquisitions
22.3.5 Certifications
22.4 Enterome Bioscience
22.4.1 Financial Analysis
22.4.2 Product Portfolio
22.4.3 Demographic Reach and Achievements
22.4.4 Mergers and Acquisitions
22.4.5 Certifications
22.5 Horizon Therapeutics
22.5.1 Financial Analysis
22.5.2 Product Portfolio
22.5.3 Demographic Reach and Achievements
22.5.4 Mergers and Acquisitions
22.5.5 Certifications
22.6 Arcturus Therapeutics
22.6.1 Financial Analysis
22.6.2 Product Portfolio
22.6.3 Demographic Reach and Achievements
22.6.4 Mergers and Acquisitions
22.6.5 Certifications
22.7 Codexis
22.7.1 Financial Analysis
22.7.2 Product Portfolio
22.7.3 Demographic Reach and Achievements
22.7.4 Mergers and Acquisitions
22.7.5 Certifications
22.8 Mito Pharmaceuticals
22.8.1 Financial Analysis
22.8.2 Product Portfolio
22.8.3 Demographic Reach and Achievements
22.8.4 Mergers and Acquisitions
22.8.5 Certifications
22.9 Abbott
22.9.1 Financial Analysis
22.9.2 Product Portfolio
22.9.3 Demographic Reach and Achievements
22.9.4 Mergers and Acquisitions
22.9.5 Certifications
22.10 Bausch Health Companies
22.10.1 Financial Analysis
22.10.2 Product Portfolio
22.10.3 Demographic Reach and Achievements
22.10.4 Mergers and Acquisitions
22.10.5 Certifications
22.11 Allena Pharmaceuticals
22.11.1 Financial Analysis
22.11.2 Product Portfolio
22.11.3 Demographic Reach and Achievements
22.11.4 Mergers and Acquisitions
22.11.5 Certifications
22.12 Mylan N.V. (now part of Viatris)
22.12.1 Financial Analysis
22.12.2 Product Portfolio
22.12.3 Demographic Reach and Achievements
22.12.4 Mergers and Acquisitions
22.12.5 Certifications
22.13 Chiesi Farmaceutici S.p.A.
22.13.1 Financial Analysis
22.13.2 Product Portfolio
22.13.3 Demographic Reach and Achievements
22.13.4 Mergers and Acquisitions
22.13.5 Certifications
23 Cystinuria Market - Distribution Model (Additional Insight)
23.1 Overview
23.2 Potential Distributors
23.3 Key Parameters for Distribution Partner Assessment
24 Key Opinion Leaders (KOL) Insights (Additional Insight)
25 Company Competitiveness Analysis (Additional Insight)
25.1 Very Small Companies
25.2 Small Companies
25.3 Mid-Sized Companies
25.4 Large Companies
25.5 Very Large Companies
26 Payment Methods (Additional Insight)
26.1 Government Funded
26.2 Private Insurance
26.3 Out-of-Pocket
*Additional insights provided are customisable as per client requirements.
* The coverage of the Market Landscape section depends on the data availability and may cover a minimum of 80% of the total market. The research team strives to make this section as comprehensive as possible.

Companies Mentioned

  • Retrophin
  • Recordati Rare Diseases Inc.
  • Mission Therapeutics
  • Enterome Bioscience
  • Horizon Therapeutics
  • Arcturus Therapeutics
  • Codexis
  • Mito Pharmaceuticals
  • Abbott
  • Bausch Health Companies
  • Allena Pharmaceuticals
  • Mylan N.V. (now part of Viatris)
  • Chiesi Farmaceutici S.p.A.

Methodology

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