Marine Biopharmaceuticals: Scope and Prospects is a collaboration of experts in pharmacology, biology and biochemistry with a focus on Marine Bioprospecting. The book provides an in-depth exploration of promising pharmaceutical compounds found in various marine biota and their therapeutic applications. The comprehensive contents cover marine ecosystems, marine biopharmaceutical, and delve into the chemistry and therapeutic applications of compounds from diverse marine organisms such as seaweeds, sponges, cnidarians, bryozoans, worms, shellfish, tunicates, and fishes.
The chapters also highlight approved and marketed marine biota-derived drugs and marine biota-derived drug candidates currently under clinical trials. Marine biopharmaceutical compounds targeting SARS-CoV-2 are also covered, reflecting the latest developments in the field. The editors conclude the book by advocating for the establishment of professional grade Marine Biopharmacy courses at university level to contribute to this emerging field.
This reference serves as a guide for researchers and instructors in disciplines such as Pharmaceutical Sciences, Marine Biology, Marine Microbiology, Marine Biochemistry, and Marine Biotechnology. Moreover, it is positioned as a standard reference for libraries in colleges and universities, offering critical insights for drug companies engaged in the development of new drugs from marine biopharmaceuticals.
The chapters also highlight approved and marketed marine biota-derived drugs and marine biota-derived drug candidates currently under clinical trials. Marine biopharmaceutical compounds targeting SARS-CoV-2 are also covered, reflecting the latest developments in the field. The editors conclude the book by advocating for the establishment of professional grade Marine Biopharmacy courses at university level to contribute to this emerging field.
This reference serves as a guide for researchers and instructors in disciplines such as Pharmaceutical Sciences, Marine Biology, Marine Microbiology, Marine Biochemistry, and Marine Biotechnology. Moreover, it is positioned as a standard reference for libraries in colleges and universities, offering critical insights for drug companies engaged in the development of new drugs from marine biopharmaceuticals.
Readership
Academics, instructors and professionals in the field of pharmacology and marine science.Table of Contents
Chapter 1 Introduction- Introduction
- Role of Seas and Oceans in Human Life
- Marine Biodiversity
- Origin of Marine Drugs
- Marine Organisms as Sources of Drugs
- Need for the Production of Marine Drugs
- Pharmaceutical Marine Biodiversity and Drug Development
- Problems in the Development of New Marine Drugs
- Remedial Measures for the Supply of Bioactive Compounds
- Present Status of Marine Drug Discovery
- Scope for Active Research on the Development of Marine Drugs
- Conclusion
- Introduction
- Marine Ecosystems and Their Pharmaceutical Biodiversity
- Open Marine Ecosystem
- Deep-Sea Ecosystem
- Sandy Beach Ecosystem
- Rocky Marine Ecosystem
- Coral Reef Ecosystem
- Kelp Forest Ecosystem
- Estuarine Ecosystem
- Saltwater Wetland Ecosystem
- Mangrove Ecosystem
- Polar Marine Ecosystem
- Marine Bioactive Compounds
- Therapeutic Activities of Marine Bioactive Compounds
- Bioactive Compounds of Marine Organisms
- Chemical Classes of Marine Bioactive Compounds
- Potential Bioactive Compounds of Different Constituents of Marine Life
- Bioactivity-Based Contribution of Marine Bioactive Compounds
- Status of Isolated Marine Bioactive Compounds
- Marine Bioactive Compounds as Diagnostics and Experimental
- Tools
- Enzymes
- Green Fluorescent Protein (Gfp) and Phycoerythrin
- Okadaic Acid
- Palytoxin
- Limulus-Amoebocyte-Lysate (Lal)
- Keyhole Limpet Hemocyanin (Klh)
- Tetrodotoxin
- Marine Biopharmaceuticals
- Advantages of Biopharmaceuticals
- Generics Vs Biosimilars
- Bio-Betters
- Development of Marine Biopharmaceuticals (Development Of
- Marine Drugs)
- Green Processing Methods to Extract Biomolecules from Marine Life
- Traditional Methods
- Modern Methods
- Fermentative Extraction
- Enzymatic Extraction
- Supercritical Fluid Extraction
- Pressurized Liquid Extraction
- Subcritical Water Extraction
- Supercritical Co2 Extraction
- Pressurized Hot Water Extraction
- Pulse Electric Field-Assisted Method
- Microwave-Assisted Method
- Ultrasound-Assisted Method
- High Hydrostatic Pressure
- Extrusion-Assisted Extraction
- Membrane Separation Technologies
- Combined Extraction Techniques
- Major Problems in the Development of New Marine Pharmaceuticals (= Marine Drugs)
- How to Address the Supply Problem?
- Aquaculture
- Genetic Engineering
- Synthesis/Semi Synthesis/Modification
- Remedial Measures for the Supply of Bioactive Compounds
- Conclusion
- Introduction
- Seaweeds
- Pharmaceutically Most Important Seaweed Species
- Green Algae
- Brown Algae
- Red Algae
- The Bioactive Compounds and Their Therapeutic Activities Of
- Seaweeds
- Anticancer Activity
- Green Algae
- Brown Algae
- Red Algae
- Anticancer Compounds from Seaweeds That Are Already in Use Or
- In Advanced Clinical Trials
- Antiviral Activity
- Green Algae
- Brown Algae
- Red Algae
- Anti-Inflammatory Activity
- Green Algae
- Brown Algae
- Antioxidant Activity
- Brown Algae
- Red Algae
- Anticoagulant Activity
- Green Algae
- Brown Algae
- Red Algae
- Antidiabetic Activity (Alpha-Glucosidase Inhibitory Activity and the Anti-Hyperglycemic
- Effects)
- Brown Algae
- Red Algae
- Anti-Allergic Effects
- Ecklonia Stolonifera
- Ache and Bche Inhibitory Activity (For the Treatment of Alzheimer's Disease)
- Brown Algae
- Brown and Red Algae
- Angiotensin-Converting Enzyme (Ace) Inhibitory Activity (Angiotensin Receptor Blockers
- For Treating Cardiovascular Disorders)
- Brown Algae
- Antiaging Activity
- Cystoseira Nodicaulis, Eisenia Bicyclis and Ecklonia Kurome
- Ecklonia Cava
- Anti-Obesity Activity (Anti-Adipogenesis)
- Brown Algae
- Red Algae
- Antinociceptive Activity
- Dichotomaria Obtusata
- Neuroprotective Activity
- Hepatoprotective Activity
- Brown Algae
- Red Algae
- Antiulcer Activity
- Gracilaria Crassa and Laurencia Papillosa
- Wound Healing Activity
- Brown Alga
- Red Algae
- Immunomodulatory Activity
- Green Alga
- Brown Algae
- Red Alga
- Seagrasses
- Biomedically Important Seagrass Families and Their Species
- Cymodoceaceae
- Hydrocharitaceae
- Posidoniaceae
- Zosteraceae
- Bioactive Compounds of Seagrasses and Their Therapeutic Activities
- Bioactivities of the Sea Grass Extracts
- Anti-Inflammatory Activity
- Posidonia Oceanica
- Syringodium Filiforme and Thalassia Testudinum
- Halophila Ovalis
- Thalassodendron Ciliatum
- Antiviral Activity
- Posidonia Oceanica
- Thalassodendron Ciliatum
- Thalassia Hemprichii
- Unidentified Species of Zosteraceae Family
- Anti-Dengue Activity (Larvicidal Activity)
- Cymodocea Serrulata
- Enhalus Acoroides
- Halophila Ovalis
- Halodule Pinifolia
- Syringodium Isoetifolium
- Thalassia Hemprichii
- Thalassia Testudinum
- Lipid-Reducing Activity
- Thalassia Hemprichii
- Halophila Stipulacea
- Anti-Diabetic Activity
- Syringodium Filiforme and Thalassia Testudinum
- Halophila Stipulacea
- Thalassia Hemprichii
- Halophila Beccarii
- Halodule Uninervis
- Posidonia Oceanica
- Hepatoprotective Activity
- Thalassia Hemprichii
- Halodule Uninervis
- Cymodocea Rotundata
- Thalassodendron Ciliatum
- Anti-Aging Activity
- Posidonia Oceanica
- Mangroves
- Pharmaceutically Important Species of Mangroves
- Pharmaceutical Importance of True Mangroves
- The Bioactive Compounds of Mangroves and Their Therapeutic
- Activities
- Anticancer Activity
- Aegiceras Corniculatum
- Avicennia Alba
- Bruguiera Gymnorrhiza
- Excoecaria Agallocha
- Heritiera Littoralis
- Rhizophora Stylosa
- Sonneratia Paracaseolaris
- Xylocarpus Granatum
- Xylocarpus Spp
- Ceriops Tagal
- Bruguiera Cylindrica
- Anti-Inflammatory and Antioxidant Activities
- Avicennia Marina
- Bruguiera Gymnorhiza
Author
- Santhanam Ramesh
- Ramasamy Santhanam
- Veintramuthu Sankar
