Now fully revised and updated, Williams Textbook of Endocrinology, 15th Edition, remains your go-to reference for authoritative content on the full spectrum of adult and pediatric endocrine system disorders. World-renowned authors and editors expertly bridge the gap between basic science and clinical information, keeping you up to date with recent advances in medications, therapies, clinical trials, and more. This essential reference is a must-have resource for endocrinologists, endocrine surgeons, gynecologists, internists, pediatricians, and other clinicians who need current, comprehensive coverage of this multifaceted field.
- Presents current information in a highly illustrated, user-friendly format for quick reference.
- Includes new chapters on Skeletal Regulation of Metabolism, Digitized Approaches to Diabetes Therapeutics, and MODY and Atypical Diabetes.
- Reflects updated approaches to transgender medicine as well as new coverage of viral infections, including COVID-19.
- Covers hot topics such as personalized medicine; the latest methodologies and trends regarding cancer genomics, precision oncology, and cell biology; and updates in key areas such as adrenal dysfunction and diabetes.
- Provides state-of-the-art coverage of diabetes, metabolic syndrome, metabolic bone disorders, obesity and thyroid disease, as well as pituitary, gonadal, and adrenal disorders, and much more-all designed to help you provide optimal care to every patient.
- Features contributions from today’s thought leaders in endocrinology.
- Contains a selected reading list and highlighted key references nominated by the editors.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
Table of Contents
1. Principles of Endocrinology2. Principles of Hormone Action
3. Genetics of Endocrinology
4. Laboratory Techniques for Recognition of Endocrine Disorders
5. Neuroendocrinology
6. Pituitary Physiology and Diagnostic Evaluation
7. Pituitary Adenomas and Masses
8. Posterior Pituitary
9. Thyroid Pathophysiology and Diagnostic Evaluation
10. Hyperthyroid Disorders
11. Hypothyroidism and Thyroiditis
12. Nontoxic Diffuse Goiter, Nodular Thyroid Disorders, and Thyroid Malignancies
13. The Adrenal Cortex
14. Endocrine Hypertension
15. Physiology and Pathology of the Female Reproductive Axis
16. Hormonal Contraception
17. Testicular Disorders
18. Sexual Function and Dysfunction
19. Endocrine Changes in Pregnancy
20. Endocrinology of Fetal Development
21. Differences of Sex Development
22. Normal and Aberrant Growth in Children
23. Physiology and Disorders of Puberty
24. Transgender Endocrinology
25. Hormones and Athletic Performance
26. Endocrine Function and Aging
27. Hormones and Disorders of Mineral Metabolism
28. Endocrine Functions of Bone
29. Osteoporosis: Basic and Clinical Aspects
30. Rickets and Osteomalacia
31. Kidney Stones
32. Physiology of Insulin Secretion
33. Pathophysiology of Type 2 Diabetes Mellitus
34. Therapeutics of Type 2 Diabetes Mellitus
35. Type 1 Diabetes Mellitus
36. Digitized Approaches to Diabetes Diagnostics and Therapeutics
37. Monogenic Diabetes
38. Complications of Diabetes Mellitus
39. Hypoglycemia
40. Obesity and Neuroendocrine Control of Energy Stores
41. Disorders of Lipoprotein Metabolism
42. Endocrine Neoplasia Syndromes
43. Neuroendocrine Tumors and Disorders
44. The Immunoendocrinopathy Syndromes
45. Endocrinology of Cancer Management and Survivorship
46. Endocrinology of HIV/AIDS
47. Acute and Chronic COVID-19 and the Endocrine System
48. Endocrine Disorders of Critical Illness
Authors
Shlomo Melmed Professor of Medicine, Dean of the Medical Faculty, Cedars Sinai Health System, USA. Shlomo Melmed, MB, ChB, FRCP, MACP, is Executive VP and Dean of the Medical Faculty at Cedars-Sinai Medical Center. He leads Cedars-Sinai's research and education programs, recruiting nationally recognized faculty leadership, establishing new educational programs and maintaining the highest academic standards. Dr. Melmed holds the Helene A. and Philip E. Hixon Distinguished Chair in Investigative Medicine. An international authority on pituitary medicine, he has pioneered the discovery and application of novel treatments for endocrine tumors and has authored more than 350 peer-reviewed articles.Dr. Melmed has been a faculty leader at Cedars-Sinai for nearly 40 years and has been the health system's chief academic officer since 1998. Dr. Melmed's laboratory consistently has received competitive grant awards from the National Institutes of Health since 1980, and he has trained over 80 physicians, scientists and graduate students who occupy leading positions in academic endocrinology worldwide. He is on the editorial board of the Journal of Clinical Investigation and is also an Associate Dean of the UCLA School of Medicine. Richard J. Auchus Professor, Departments of Pharmacology and Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Endocrinology Service Chief, Ann Arbor VA Healthcare System, Ann Arbor, Michigan. Allison B. Goldfine Associate Physician, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital; Lecturer, Part-Time, Harvard Medical School, Boston, Massachusetts, Director, Translational Medicine Cardiometabolic Disease, Novartis Institute of Biomedical Research, Cambridge, Massachusetts. Clifford J. Rosen Professor of Medicine, Tufts University School of Medicine, Boston, Massachusetts. Peter A. Kopp Professor of Medicine, Division of Endocrinology, Diabetology, and Metabolism, University of Lausanne, Lausanne, Switzerland; Adjunct Professor, Division of Endocrinology, Metabolism, and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.