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Metabolomics of Bladder Cancer. An Emerging Application

  • Book

  • September 2024
  • Elsevier Science and Technology
  • ID: 5947870

Metabolomics of Bladder Cancer: An Emerging Application offers insights into the latest research methodologies and potential therapeutic applications. The book examines how applied research on the discovery of metabolomic biomarkers with prognostic and predictive value is needed to stratify patients into different risk groups, minimizing overtreatment and the risk of drug resistance development. In eight chapters, the book gives an in-depth analysis of recent findings in both fundamental and applied research, with a focus on the metabolomics approach and its potential for identifying major metabolic pathways that characterize various diseases and physiological states. It intuitively leads from the discovery of biomarkers for bladder cancer, to the metabolisms of glutamine and fatty acids and finalizes with a chapter on the metabolic effect of cancer therapy. Overall, this book is a comprehensive and insightful resource for researchers, clinicians, and academic professionals interested in the latest developments in bladder cancer research.

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Table of Contents

1. Contribution of Metabolomics in the Discovery of Biomarker for Bladder cancer
2. Role of Tobacco on Bladder Cancer Pathways
3. Regulation of Glycolysis in Bladder Cancer
4. Metabolism of Fatty Acid
5. Regulation of Pentose Phosphate Pathway
6. Mitochondrial Metabolism
7. Metabolic Effect of Cancer Therapy
8. Metabolomics and Racial Disparities in Bladder Cancer Carcinogensis

Authors

Vishwajeet Singh Professor, Department of Urology, King George's Medical University, Chowk, Lucknow, Uttar Pradesh, India. Dr. Vishwajeet Singh is a well-known Urology professor who specializes in Uro-Oncology, Female Urology (Urogynecology), and Renal Transplantation. He currently works at King George's Medical University in Lucknow, Uttar Pradesh, India. Dr. Singh has made important contributions to the field of Urology through his research and publications. Uro-Oncology, Female Urology (Urogynecology), and Renal Transplantation are among his primary research interests. He has published multiple research papers in renowned journals over the previous ten years, demonstrating his skill and dedication to expanding knowledge in his profession. Mukul Kumar Singh Ph.D. Scholar, ICMR-SRF, Department of Urology, King George's Medical University, Chowk, Lucknow, Uttar Pradesh, India. Mukul Kumar Singh is a Ph.D. Scholar and early career researcher at King George's Medical University's Department of Urology. He is actively researching the molecular mechanisms underlying immunotherapy failure in bladder cancer under the supervision of Dr. V. Singh. His research focuses on tumour metabolite change and proliferative mechanisms. He published several articles and book chapters on immunotherapeutic strategies and is a member of the European Association for Cancer Research (EACR), the American Society for Clinical Oncology (ASCO), the European Society for Medical Oncology (ESMO), and the Agricultural Technology Development Society (ATDS)