African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part One: Cancer Chemoresistance, Screening, Methods, and the Updated cut-off Points for the Classification of Natural Cytotoxic Products, Volume 111 offers an overview of the potential of African medicinal plants as a source of anticancer agents to overcome with an emphasis on cancer drug resistance. Based on the collected data, the book also offers a rational classification basis for the cytotoxic activity of natural products. The general knowledge of state-of-the-art of cancer drug resistance globally and the screening methods for cytotoxic agents are described.
This book clearly identifies the best African medicinal plants that could be useful for the development of efficient herbal drugs, as well as the best phytochemicals that could be explored as potential pharmaceuticals to efficiently tackle cancers and their refractory phenotypes. The book appears a unique tool for Scientists for anticancer drug discovery from the exceptional flora of Africa.
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Table of Contents
1. Cancer, global burden, and drug resistanceHermann Fongang
2. Screening methods of anticancer agents from natural source
Aim� G. Fankam and Victor Kuete
3. Established anticancer agents from plants
Armel J. Seukep and Victor Kuete
4. African medicinal plants and their derivative as the source of potent anti-leukemic products: rationale classification of naturally occurring anticancer agents
Victor Kuete
5. Potential of African medicinal plants against breast cancer and resistant phenotypes
Victor Kuete
6. Fighting colorectal cancer and its drug resistance with the resources of the flora of Africa
Victor Kuete
7. African medicinal plants and their constituents can fight glioblastoma and its drug resistance
Armelle T. Mbaveng and Victor Kuete
8. Fighting melanoma and resistant phenotypes African medicinal plants and their phytoconstituents
Brice E. N. Wamba, Armelle T. Mbaveng and Victor Kuete
9. Potential of African plants and their derived phytochemicals against hepatocellular carcinoma
Victor Kuete
10. Potential of African medicinal plants and their constituents to fight prostate cancer: An overview
Victor Kuete
11. Review of the potential of African medicinal plants and their derived products against pancreatic cancer
Victor Kuete
12. Activity of African medicinal plants against cervical cancer cells
Paul Nayim, Armelle T. Mbaveng and Victor Kuete
13. African medicinal plants and their phytochemicals can be used to combat lung cancer
Victor Kuete
14. Modes and mechanisms of action of potent cytotoxic plant-derived products from the flora of Africa
Victor Kuete
