Bone Void Fillers Global Market Report 2024

The bone void fillers market size has grown strongly in recent years. It will grow from $3.26 billion in 2023 to $3.53 billion in 2024 at a compound annual growth rate (CAGR) of 8.1%. The growth observed in the historical period can be attributed to several factors, including the increasing prevalence of bone-related diseases, an aging population, sports injuries, a rise in healthcare expenditures, and increased funding from both private and government organizations for the development of the healthcare sector.

The bone void fillers market size is expected to see strong growth in the next few years. It will grow to $4.58 billion in 2028 at a compound annual growth rate (CAGR) of 6.7%. The anticipated growth in the forecast period can be attributed to various factors, including the expanding applications in regenerative medicine, an increased incidence of lifestyle diseases, a rise in orthopedic surgeries, the increased adoption of minimally invasive surgical techniques, and the growing trend towards personalized medicine and tailored treatments. Key trends expected in the forecast period encompass advancements in medical technology, emphasis on biocompatibility and innovation in bone void fillers, customization and 3D printing in medical applications, technological advancements in surgical procedures, and improvements in imaging and surgical planning techniques.

The escalating burden of bone diseases is poised to drive the growth of the bone void filler market in the foreseeable future. Bone diseases encompass a range of medical conditions affecting the structure and functionality of bones, resulting in abnormalities such as weakness, deformity, pain, and impaired growth or repair. Bone void fillers play a crucial role in treating these conditions by facilitating bone growth and repair in areas where bone damage occurs, thereby promoting quicker healing, reducing pain, and enhancing the overall success of bone-related treatments. For instance, projections from the Institute for Health Metrics and Evaluation (IHME) in August 2023 indicate a significant rise in osteoarthritis cases, with knee osteoarthritis expected to surge by 75% and hand osteoarthritis by 50% by 2050. Consequently, the mounting burden of bone diseases serves as a key driver propelling the growth of the bone void filler market.

Prominent entities in the bone void fillers market are strategically focusing on the development of innovative products to bolster their market competitiveness and profitability. One such innovation gaining traction is carbohydrate polymer bone graft substitutes - a synthetic material engineered to mimic the natural bone structure and promote the body's bone healing and regeneration processes in areas of bone loss. For example, in May 2023, Royal Biologics, a leading orthobiologics and life science company based in the United States, introduced Bio-Reign 3D, a bone graft substitute crafted from a hyper-crosslinked natural carbohydrate polymer. This advanced material provides an optimal environment for cell growth and blood vessel formation, thereby facilitating bone regeneration. Notably, Bio-Reign 3D transitions from radiolucent to radiopaque as the healing process progresses, allowing for effective monitoring of the healing process. Additionally, it offers superior compression, tensile strength, and ease of use, ensuring efficient shaping and application of the graft. By incorporating such innovative solutions, companies aim to address the evolving needs of patients and healthcare providers, contributing to the continued growth and advancement of the bone void filler market.

In April 2023, Henry Schein Inc., a leading healthcare company headquartered in the United States, acquired a majority ownership stake in Biotech Dental SAS for an undisclosed sum. This strategic acquisition is poised to bolster Henry Schein's digital integration efforts by leveraging Biotech Dental's cutting-edge software solutions alongside its product portfolio. The integration aims to streamline workflows and enhance patient outcomes while facilitating global expansion, particularly in the implant and orthodontics sectors. Biotech Dental, headquartered in France, is renowned for its expertise in providing bone void fillers and stands as a valuable addition to Henry Schein's portfolio.

Major companies operating in the bone void fillers market report are Johnson & Johnson, Medtronic plc, Danaher Corporation, Heraeus Group, Stryker Corporation, Baxter International Inc., B. Braun Mulsungen AG, Huntsman Corporation, Zimmer Biomet Holdings Inc., Smith and Nephew plc, Arthrex Inc., Globus Medical Inc., NuVasive Inc., Orthofix Medical Inc., Exactech Inc., Biocomposites Ltd., Mitsubishi Plastics Inc., Aziyo Biologics Inc., Bone Support AB, Collagen Matrix Inc., Royal Biologics Inc., FlexForm Technologies, Fiberon LLC, Orthorebirth Co. Ltd, Vivex Biologics.

North America was the largest region in the bone void fillers market in 2023. The regions covered in the bone void fillers market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the bone void fillers market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Bone void fillers are materials utilized to fill defects or discontinuities in bone tissue, often arising from pathologic processes such as trauma, degenerative conditions, or neoplastic conditions. These fillers can be either synthetic or natural, serving as an osteoconductive matrix to facilitate the healing of bone.

The main types of bone void fillers include demineralized bone matrix, calcium phosphate bone graft substitutes, collagen matrix, and others. Calcium-phosphate bone graft substitutes typically consist of tricalcium phosphate or hydroxyapatite, which is the primary mineral found in bone. These fillers are available in various forms such as gel and putty, granules, and others. They find applications in various medical procedures such as bone fractures and spine fusion, and are used by different end-users, including hospitals and specialty clinics.

The bone void fillers market research report is one of a series of new reports that provides bone void fillers market statistics, including bone void fillers industry global market size, regional shares, competitors with a bone void fillers market share, detailed bone void fillers market segments, market trends and opportunities, and any further data you may need to thrive in the bone void fillers industry. This bone void fillers market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The bone void filler market consists of sales of demineralized bone matrix, bioactive glass, bone morphogenetic proteins, and human bone (autografts and allografts). Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.


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