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Autosomal Dominant Hypocalcemia Type 1 Market

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    Report

  • 200 Pages
  • May 2024
  • Region: Global
  • Erevna Healthcare
  • ID: 5968542
The market will grow as a result of growing attention to orphan pharmaceuticals, rising awareness of rare diseases, technological breakthroughs, and an increase in strategic alliances and collaborations. Improved awareness among healthcare providers regarding rare genetic disorders such as ADH1 has resulted in higher diagnostic rates. Advances in genetic testing technology have made it easier to identify mutations in the calcium-sensing receptor gene (CASR), allowing for early discovery and diagnosis of ADH1 cases.

Regulatory agencies in several countries provide incentives to pharmaceutical companies to explore medicines for rare disorders such as ADH1. These incentives could include prolonged market exclusivity, tax breaks, and simplified regulatory routes to encourage investment in orphan medication development. For instance, in January 2024, Amgen reported good results from a Phase 2 trial of a potential treatment for uncommon endocrine disorders such as ADH1.

By treatment type, the calcium analogs segment accounted for the highest revenue-grossing segment in the global autosomal dominant hypocalcemia type 1 (ADH1) market in 2023 owing to the growing demand for effective symptom management and calcium regulation therapies among ADH1 patients. For instance, in October 2023, Eli Lilly announced the start of a Phase 3 trial for a potential treatment for uncommon endocrine illnesses, which may include ADH1. Additionally, the Others segment is predicted to grow at the fastest CAGR during the forecast period owing to the rising awareness about the role of hormonal imbalances in ADH1 pathogenesis and the development of innovative hormone-based treatment options.

By end-user, the hospitals segment accounted for the highest revenue-grossing segment in the global autosomal dominant hypocalcemia type 1 (ADH1) market in 2023 owing to the increased patient admissions for diagnostic tests, treatment, and ongoing management of ADH1-related complications in hospital settings. For instance, in September 2023, Novartis announced the start of a Phase 1 trial for a potential gene therapy method for uncommon endocrine illnesses, including ADH1. Additionally, the clinics segment is predicted to grow at the fastest CAGR during the forecast period owing to the rising preference for outpatient care, increased availability of specialized clinics, and improved access to ADH1 diagnosis and treatment services in community healthcare settings.

North American region is anticipated to have the highest revenue share during the forecast period owing to the region's advanced healthcare infrastructure, high prevalence of rare genetic disorders, such as ADH1, and extensive research and development activities in the pharmaceutical and biotechnology sectors. Additionally, the Asia Pacific region is predicted to grow at the fastest CAGR during the forecast period owing to the increasing awareness, improving healthcare infrastructure, rising healthcare expenditure, and expanding patient population with rare genetic disorders like ADH1. For instance, in February 2024, Pfizer signed an exclusive four-year research cooperation with Beam Therapeutics Inc., a biotechnology startup that specializes in precision genetic therapies via base editing.

This extensive research report concentrates on the size and projections of the global and regional markets from 2023 to 2034.

Report Scope:

  • Base Year: 2023
  • Forecast Period: 2024-2034
  • Study Coverage
  • Market Forecast by Treatment Type, and End-User
  • Market Forecast for 5 Regions and 17+ Countries
  • North America (U.S. and Canada)
  • Europe (Germany, France, UK, Spain, Italy, Russia, Rest of Europe)
  • Asia Pacific (China, Japan, India, Australia, South Korea, Rest of APAC)
  • Latin America (Brazil, Mexico, Argentina, Rest of LATAM)
  • MEA (South Africa, GCC, Rest of MEA)
  • Exhaustive Company Profiles of the Top 10+ Major Market Players

Segmentation: Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Report 2023 - 2034

Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Analysis & Forecast by Treatment Type 2023 - 2034 (Revenue USD Bn)

  • Calcium Analog
  • Vitamin Analogs
  • Others

Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Analysis & Forecast by End-User 2023 - 2034 (Revenue USD Bn)

  • Hospitals
  • Clinics
  • Others

Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Analysis & Forecast by Region 2023 - 2034 (Revenue USD Bn)

  • North America
  • U.S.
  • Canada
  • Europe
  • Germany
  • France
  • UK
  • Spain
  • Italy
  • Rest of Europe
  • Asia Pacific
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of APAC
  • Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of LATAM
  • Middle East & Africa
  • South Africa
  • GCC
  • Rest of MEA

Table of Contents

1. Research Methodology
1.1. Study Objectives
1.2. Study Scope
1.3. Research Assumptions
1.4. Research Framework
2. Introduction
2.1. Market Definition
2.2. Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Overview
3. Executive Summary
4. Market Environment Analysis
4.1. Porter’s 5 Forces Analysis
4.2. PESTEL Analysis
4.3. SWOT Analysis
5. Market Dynamics
5.1. Drivers Analysis
5.2. Restraints Analysis
5.3. Opportunities Analysis
5.4. Threats Analysis
5.5. Trend Analysis
6. COVID-19 Impact Analysis
7. Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market: Treatment Type Estimates & Trend Analysis
7.1. Treatment Type Segment Opportunity Analysis
7.2. Calcium Analog
7.2.1. Calcium Analog Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
7.3. Vitamin Analogs
7.3.1. Vitamin Analogs Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
7.4. Others
7.4.1. Others Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
8. Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market: End-User Estimates & Trend Analysis
8.1. End-User Segment Opportunity Analysis
8.2. Hospitals
8.2.1. Hospitals Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
8.3. Clinics
8.3.1. Clinics Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
8.4. Others
8.4.1. Others Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9. Regional Market Analysis
9.1. Regional Market Opportunity Analysis
10. North America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
10.1. North America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
10.1.1. North America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
10.1.2. North America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
10.1.3. North America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
10.1.4. North America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
10.2. U.S. Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
10.2.1. U.S. Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
10.2.2. U.S. Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
10.2.3. U.S. Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
10.3. Canada Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
10.3.1. Canada Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
10.3.2. Canada Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
10.3.3. Canada Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
11. Europe Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.1. Europe Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.1.1. Europe Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.1.2. Europe Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
11.1.3. Europe Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
11.1.4. Europe Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
11.2. Germany Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.2.1. Germany Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.2.2. Germany Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
11.2.3. Germany Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
11.3. UK Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.3.1. UK Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.3.2. UK Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
11.3.3. UK Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
11.4. France Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.4.1. France Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.4.2. France Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
11.4.3. France Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
11.5. Spain Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.5.1. Spain Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.5.2. Spain Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
11.5.3. Spain Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
11.6. Italy Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.6.1. Italy Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.6.2. Italy Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
11.6.3. Italy Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
11.7. Rest of Europe Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
11.7.1. Rest of Europe Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.7.2. Rest of Europe Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
11.7.3. Rest of Europe Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
12. Asia Pacific Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.1. Asia Pacific Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.1.1. Asia Pacific Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.1.2. Asia Pacific Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
12.1.3. Asia Pacific Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
12.1.4. Asia Pacific Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
12.2. Japan Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.2.1. Japan Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.2.2. Japan Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
12.2.3. Japan Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
12.3. China Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.3.1. China Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.3.2. China Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
12.3.3. China Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
12.4. India Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.4.1. India Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.4.2. India Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
12.4.3. India Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
12.5. South Korea Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.5.1. South Korea Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.5.2. South Korea Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
12.5.3. South Korea Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
12.6. Australia Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.6.1. Australia Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.6.2. Australia Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
12.6.3. Australia Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
12.7. Rest of Asia Pacific Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
12.7.1. Rest of Asia Pacific Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.7.2. Rest of Asia Pacific Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
12.7.3. Rest of Asia Pacific Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
13. Latin America Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
13.1. Latin America Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
13.1.1. Latin America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.1.2. Latin America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
13.1.3. Latin America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
13.1.4. Latin America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
13.2. Brazil Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
13.2.1. Brazil Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.2.2. Brazil Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
13.2.3. Brazil Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
13.3. Mexico Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
13.3.1. Mexico Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.3.2. Mexico Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
13.3.3. Mexico Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
13.4. Argentina Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
13.4.1. Argentina Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.4.2. Argentina Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
13.4.3. Argentina Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
13.5. Rest of Latin America Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
13.5.1. Rest of Latin America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.5.2. Rest of Latin America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
13.5.3. Rest of Latin America Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
14. MEA Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
14.1. MEA Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
14.1.1. MEA Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.1.2. MEA Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
14.1.3. MEA Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
14.1.4. MEA Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
14.2. GCC Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
14.2.1. GCC Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.2.2. GCC Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
14.2.3. GCC Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
14.3. South Africa Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
14.3.1. South Africa Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.3.2. South Africa Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
14.3.3. South Africa Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
14.4. Rest of MEA Global Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market
14.4.1. Rest of MEA Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.4.2. Rest of MEA Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By Treatment Type, 2023-2034 (Revenue USD Bn)
14.4.3. Rest of MEA Autosomal Dominant Hypocalcemia Type 1 (ADH1) Market Size and Forecast, By End-User, 2023-2034 (Revenue USD Bn)
15. Competitor Analysis
15.1. Company Market Share Analysis, 2023
15.2. Major Recent Developments
16. Company Profiles
16.1. Amgen Inc.
16.2. Eli Lilly and Company
16.3. Novartis AG
16.4. Merck & Co., Inc.
16.5. Pfizer Inc.
16.6. AbbVie Inc.
16.7. Shire (a subsidiary of Takeda Pharmaceutical Company Limited)
16.8. Sanofi
16.9. Roche Holding AG
16.10. Bayer AG
16.11. AstraZeneca PLC
16.12. Johnson & Johnson
16.13. Teva Pharmaceutical Industries Ltd.
16.14. BioMarin Pharmaceutical Inc.
16.15. Kyowa Kirin Co., Ltd.
17. Conclusion18. Recommendations

Companies Mentioned

  • Amgen Inc.
  • Eli Lilly and Company
  • Novartis AG
  • Merck & Co. Inc.
  • Pfizer Inc.
  • AbbVie Inc.
  • Shire (a subsidiary of Takeda Pharmaceutical Company Limited)
  • Sanofi
  • Roche Holding AG
  • Bayer AG
  • AstraZeneca PLC
  • Johnson & Johnson
  • Teva Pharmaceutical Industries Ltd.
  • BioMarin Pharmaceutical Inc.
  • Kyowa Kirin Co.