The 7 major hemophilia A markets reached a value of US$ 10,288.7 Million in 2023. Looking forward, the publisher expects the 7MM to reach US$ 28,447.2 Million by 2034, exhibiting a growth rate (CAGR) of 11.96% during 2023-2034.
The hemophilia A market has been comprehensively analyzed in this report titled "Hemophilia A Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hemophilia A refers to a genetic bleeding disorder characterized by a deficiency or dysfunction of clotting factor VIII (FVIII). It is the most common type of hemophilia, accounting for approximately 80% of all cases. Some of the common symptoms associated with the ailment include prolonged bleeding after injuries, surgeries, or dental procedures; frequent nosebleeds; easy bruising; spontaneous joint or muscle bleeding; and, in severe instances, potentially life-threatening internal bleeding. Individuals suffering from hemophilia A may also experience excessive bleeding from minor cuts or trauma, as well as prolonged bleeding from the gums or gastrointestinal tract. During the diagnosis, a healthcare provider will assess the patient's medical records, family history, and symptoms suggestive of abnormal bleeding. Blood tests will also be performed to measure the levels of clotting factor VIII activity in the blood. A significantly reduced level of FVIII confirms the diagnosis of hemophilia A. In some cases, genetic testing may be conducted to identify specific mutations in the F8 gene. Additionally, various other laboratory tests, such as coagulation studies and bleeding time evaluations, are performed to assess the overall bleeding profile.
The rising cases of genetic mutations that result in a deficiency or dysfunction of clotting factor VIII, which is essential for normal blood clotting, are primarily driving the hemophilia A market. Additionally, the inflating demand for hemostatic agents, such as antifibrinolytic drugs, as adjunctive therapy to enhance clot stability and minimize bleeding is creating a positive outlook for the market. Furthermore, the escalating utilization of prophylactic treatment that involves regular infusions of clotting factor VIII to prevent or reduce the frequency and severity of bleeding is also bolstering the market growth. Besides this, the emerging popularity of extended half-life (EHL) clotting factors, since they offer the advantage of increased convenience and potentially improved protection against bleeding episodes as compared to standard clotting factors, is acting as another significant growth-inducing factor. Moreover, the rising usage of immune tolerance induction therapy, which entails high-dose and frequent infusions of FVIII over an extended period to desensitize the immune system as well as induce tolerance to FVIII, is expected to drive the hemophilia A market in the coming years.
This report provides an exhaustive analysis of the hemophilia A market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hemophilia A and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hemophilia A market in any manner.
The hemophilia A market has been comprehensively analyzed in this report titled "Hemophilia A Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hemophilia A refers to a genetic bleeding disorder characterized by a deficiency or dysfunction of clotting factor VIII (FVIII). It is the most common type of hemophilia, accounting for approximately 80% of all cases. Some of the common symptoms associated with the ailment include prolonged bleeding after injuries, surgeries, or dental procedures; frequent nosebleeds; easy bruising; spontaneous joint or muscle bleeding; and, in severe instances, potentially life-threatening internal bleeding. Individuals suffering from hemophilia A may also experience excessive bleeding from minor cuts or trauma, as well as prolonged bleeding from the gums or gastrointestinal tract. During the diagnosis, a healthcare provider will assess the patient's medical records, family history, and symptoms suggestive of abnormal bleeding. Blood tests will also be performed to measure the levels of clotting factor VIII activity in the blood. A significantly reduced level of FVIII confirms the diagnosis of hemophilia A. In some cases, genetic testing may be conducted to identify specific mutations in the F8 gene. Additionally, various other laboratory tests, such as coagulation studies and bleeding time evaluations, are performed to assess the overall bleeding profile.
The rising cases of genetic mutations that result in a deficiency or dysfunction of clotting factor VIII, which is essential for normal blood clotting, are primarily driving the hemophilia A market. Additionally, the inflating demand for hemostatic agents, such as antifibrinolytic drugs, as adjunctive therapy to enhance clot stability and minimize bleeding is creating a positive outlook for the market. Furthermore, the escalating utilization of prophylactic treatment that involves regular infusions of clotting factor VIII to prevent or reduce the frequency and severity of bleeding is also bolstering the market growth. Besides this, the emerging popularity of extended half-life (EHL) clotting factors, since they offer the advantage of increased convenience and potentially improved protection against bleeding episodes as compared to standard clotting factors, is acting as another significant growth-inducing factor. Moreover, the rising usage of immune tolerance induction therapy, which entails high-dose and frequent infusions of FVIII over an extended period to desensitize the immune system as well as induce tolerance to FVIII, is expected to drive the hemophilia A market in the coming years.
This report provides an exhaustive analysis of the hemophilia A market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hemophilia A and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hemophilia A market in any manner.
Time Period of the Study
- Base Year: 2023
- Historical Period: 2018-2023
- Market Forecast: 2024-2034
Countries Covered
- United States
- Germany
- France
- United Kingdom
- Italy
- Spain
- Japan
Analysis Covered Across Each Country
- Historical, current, and future epidemiology scenario
- Historical, current, and future performance of the hemophilia A market
- Historical, current, and future performance of various therapeutic categories in the market
- Sales of various drugs across the hemophilia A market
Competitive Landscape:
This report also provides a detailed analysis of the current hemophilia A marketed drugs and late-stage pipeline drugs.In-Market Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Key Questions Answered in this Report:
Market Insights
- How has the hemophilia A market performed so far and how will it perform in the coming years?
- What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
- What was the country-wise size of the hemophilia A market across the seven major markets in 2023 and what will it look like in 2034?
- What is the growth rate of the hemophilia A market across the seven major markets and what will be the expected growth over the next ten years?
- What are the key unmet needs in the market?
Epidemiology Insights
- What is the number of prevalent cases (2018-2034) of hemophilia A across the seven major markets?
- What is the number of prevalent cases (2018-2034) of hemophilia A by age across the seven major markets?
- What is the number of prevalent cases (2018-2034) of hemophilia A by gender across the seven major markets?
- How many patients are diagnosed (2018-2034) with hemophilia A across the seven major markets?
- What is the size of the hemophilia A patient pool (2018-2023) across the seven major markets?
- What would be the forecasted patient pool (2024-2034) across the seven major markets?
- What are the key factors driving the epidemiological trend of hemophilia A?
- What will be the growth rate of patients across the seven major markets?
Hemophilia A: Current Treatment Scenario, Marketed Drugs and Emerging Therapies
- What are the current marketed drugs and what are their market performance?
- What are the key pipeline drugs and how are they expected to perform in the coming years?
- How safe are the current marketed drugs and what are their efficacies?
- How safe are the late-stage pipeline drugs and what are their efficacies?
- What are the current treatment guidelines for hemophilia A drugs across the seven major markets?
- Who are the key companies in the market and what are their market shares?
- What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the hemophilia A market?
- What are the key regulatory events related to the hemophilia A market?
- What is the structure of clinical trial landscape by status related to the hemophilia A market?
- What is the structure of clinical trial landscape by phase related to the hemophilia A market?
- What is the structure of clinical trial landscape by route of administration related to the hemophilia A market?
Table of Contents
1 Preface3 Executive Summary6 Patient Journey9 Hemophilia A - Unmet Needs10 Hemophilia A - Key Endpoints of Treatment13. Hemophilia A - Attribute Analysis of Key Marketed and Pipeline Drugs16 Hemophilia A - Recent Events and Inputs From Key Opinion Leaders18 Hemophilia A Market - Strategic Recommendations19 Appendix
2 Scope and Methodology
4 Hemophilia A - Introduction
5 Hemophilia A - Disease Overview
7 Hemophilia A - Epidemiology and Patient Population
8 Hemophilia A - Treatment Algorithm, Guidelines, and Medical Practices
11 Hemophilia A - Marketed Products
12 Hemophilia A - Pipeline Drugs
14. Hemophilia A - Clinical Trial Landscape
15 Hemophilia A - Market Scenario
17 Hemophilia A Market - SWOT Analysis
Methodology
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Table Information
Report Attribute | Details |
---|---|
No. of Pages | 131 |
Published | May 2024 |
Forecast Period | 2023 - 2034 |
Estimated Market Value ( USD | $ 10288.7 Million |
Forecasted Market Value ( USD | $ 28447.2 Million |
Compound Annual Growth Rate | 9.7% |
Regions Covered | Global |