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Advanced Melanoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

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    Report

  • 130 Pages
  • May 2024
  • Region: Global
  • IMARC Group
  • ID: 5970057
The 7 major advanced melanoma markets reached a value of US$ 3.9 Billion in 2023. Looking forward, the publisher expects the 7MM to reach US$ 10.0 Billion by 2034, exhibiting a growth rate (CAGR) of 11.03% during 2023-2034.

The advanced melanoma market has been comprehensively analyzed in this report titled "Advanced Melanoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Advanced melanoma, also known as stage III or stage IV melanoma, is a type of skin cancer that has spread beyond the original tumor and nearby lymph nodes to distant organs or lymph nodes. Some of the common symptoms include the presence of a large or growing mole or skin lesion, changes in the size, shape, or color of existing moles, ulceration or bleeding of the skin, itching, pain, or tenderness in the affected area, swollen lymph nodes, development of new lumps or nodules, etc. As advanced melanoma can spread to distant organs, indications may also include respiratory difficulties, bone pain, neurological symptoms, abdominal discomfort, etc. The diagnosis of the ailment typically involves a comprehensive evaluation that combines clinical examination, imaging tests, and biopsy confirmation. A dermatologist or oncologist may conduct a thorough physical exam, assessing the characteristics of skin lesions and checking for enlarged lymph nodes. Various imaging studies, such as computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), etc., help determine the extent of the disease and identify possible metastases. Additionally, numerous molecular diagnostic techniques, including genetic testing and biomarker analysis, may be performed to guide treatment decisions.

The increasing cases of prolonged sun exposure and severe sunburns, especially during childhood or adolescence, are primarily driving the advanced melanoma market. In addition to this, the rising prevalence of numerous associated risk factors, including genetic mutations, weakened immune systems, presence of atypical moles, etc., is also creating a positive outlook for the market. Moreover, the widespread adoption of novel targeted inhibitors, such as vemurafenib and dabrafenib, that specifically target genetic mutations or molecular abnormalities present in melanoma cells is further bolstering the market growth. Apart from this, the inflating application of adoptive cell transfer (ACT) therapy, which involves harvesting a patient's immune cells, modifying them to enhance their cancer-fighting abilities, and then reintroducing them into the body, where they can attack melanoma cells more effectively, is also acting as another significant growth-inducing factor. Additionally, the emerging popularity of reflectance confocal microscopy, since it aids in the non-invasive evaluation of suspicious skin lesions, thereby allowing dermatologists to visualize architectural features and cellular structures within the skin layers, is expected to drive the advanced melanoma market during the forecast period.

This report provides an exhaustive analysis of the advanced melanoma market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for advanced melanoma and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the advanced melanoma market in any manner.

Time Period of the Study

  • Base Year: 2023
  • Historical Period: 2018-2023
  • Market Forecast: 2024-2034

Countries Covered

  • United States
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Japan

Analysis Covered Across Each Country

  • Historical, current, and future epidemiology scenario
  • Historical, current, and future performance of the advanced melanoma market
  • Historical, current, and future performance of various therapeutic categories in the market
  • Sales of various drugs across the advanced melanoma market

Competitive Landscape:

This report also provides a detailed analysis of the current advanced melanoma marketed drugs and late-stage pipeline drugs.

In-Market Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:

Market Insights

  • How has the advanced melanoma market performed so far and how will it perform in the coming years?
  • What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
  • What was the country-wise size of the advanced melanoma market across the seven major markets in 2023 and what will it look like in 2034?
  • What is the growth rate of the advanced melanoma market across the seven major markets and what will be the expected growth over the next ten years?
  • What are the key unmet needs in the market?

Epidemiology Insights

  • What is the number of prevalent cases (2018-2034) of advanced melanoma across the seven major markets?
  • What is the number of prevalent cases (2018-2034) of advanced melanoma by age across the seven major markets?
  • What is the number of prevalent cases (2018-2034) of advanced melanoma by gender across the seven major markets?
  • How many patients are diagnosed (2018-2034) with advanced melanoma across the seven major markets?
  • What is the size of the advanced melanoma patient pool (2018-2023) across the seven major markets?
  • What would be the forecasted patient pool (2024-2034) across the seven major markets?
  • What are the key factors driving the epidemiological trend of advanced melanoma?
  • What will be the growth rate of patients across the seven major markets?

Advanced Melanoma: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

  • What are the current marketed drugs and what are their market performance?
  • What are the key pipeline drugs and how are they expected to perform in the coming years?
  • How safe are the current marketed drugs and what are their efficacies?
  • How safe are the late-stage pipeline drugs and what are their efficacies?
  • What are the current treatment guidelines for advanced melanoma drugs across the seven major markets?
  • Who are the key companies in the market and what are their market shares?
  • What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the advanced melanoma market?
  • What are the key regulatory events related to the advanced melanoma market?
  • What is the structure of clinical trial landscape by status related to the advanced melanoma market?
  • What is the structure of clinical trial landscape by phase related to the advanced melanoma market?
  • What is the structure of clinical trial landscape by route of administration related to the advanced melanoma market?
This product will be updated with the latest data at the time of order. Consequently, dispatch time for this product will be 7-10 business days.

Table of Contents

1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Advanced Melanoma - Introduction
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 Advanced Melanoma - Disease Overview
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 Patient Journey
7 Advanced Melanoma - Epidemiology and Patient Population
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (2018-2034)
7.2.4 Epidemiology by Gender (2018-2034)
7.2.5 Diagnosed Cases (2018-2034)
7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (2018-2034)
7.3.4 Epidemiology by Gender (2018-2034)
7.3.5 Diagnosed Cases (2018-2034)
7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (2018-2034)
7.4.4 Epidemiology by Gender (2018-2034)
7.4.5 Diagnosed Cases (2018-2034)
7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (2018-2034)
7.5.4 Epidemiology by Gender (2018-2034)
7.5.5 Diagnosed Cases (2018-2034)
7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (2018-2034)
7.6.4 Epidemiology by Gender (2018-2034)
7.6.5 Diagnosed Cases (2018-2034)
7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (2018-2034)
7.7.4 Epidemiology by Gender (2018-2034)
7.7.5 Diagnosed Cases (2018-2034)
7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (2018-2034)
7.8.4 Epidemiology by Gender (2018-2034)
7.8.5 Diagnosed Cases (2018-2034)
7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (2018-2034)
7.9.4 Epidemiology by Gender (2018-2034)
7.9.5 Diagnosed Cases (2018-2034)
7.9.6 Patient Pool/Treated Cases (2018-2034)
8 Advanced Melanoma - Treatment Algorithm, Guidelines, and Medical Practices
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 Advanced Melanoma - Unmet Needs10 Advanced Melanoma - Key Endpoints of Treatment
11 Advanced Melanoma - Marketed Products
11.1 List of Advanced Melanoma Marketed Drugs Across the Top 7 Markets
11.1.1 Opdualag (Nivolumab/relatlimab) - Bristol-Myers Squibb
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
11.1.2 Tecentriq (Atezolizumab) - Genentech
11.1.2.1 Drug Overview
11.1.2.2 Mechanism of Action
11.1.2.3 Regulatory Status
11.1.2.4 Clinical Trial Results
11.1.2.5 Sales Across Major Markets
11.1.3 Imlygic (Talimogene laherparepvec) - Amgen
11.1.3.1 Drug Overview
11.1.3.2 Mechanism of Action
11.1.3.3 Regulatory Status
11.1.3.4 Clinical Trial Results
11.1.3.5 Sales Across Major Markets
11.1.4 Sylatron (Peginterferon alfa-2b) - Enzon/Merck & Co.
11.1.4.1 Drug Overview
11.1.4.2 Mechanism of Action
11.1.4.3 Regulatory Status
11.1.4.4 Clinical Trial Results
11.1.4.5 Sales Across Major Markets
11.1.5 Yervoy (Ipilimumab) - Bristol Myers Squibb
11.1.5.1 Drug Overview
11.1.5.2 Mechanism of Action
11.1.5.3 Regulatory Status
11.1.5.4 Clinical Trial Results
11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.
12 Advanced Melanoma - Pipeline Drugs
12.1 List of Advanced Melanoma Pipeline Drugs Across the Top 7 Markets
12.1.1 LTX315 - Lytix Biopharma
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 Botensilimab - Agenus
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 Tebentafusp - Immunocore
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
12.1.4 APX005M - Apexigen
12.1.4.1 Drug Overview
12.1.4.2 Mechanism of Action
12.1.4.3 Clinical Trial Results
12.1.4.4 Safety and Efficacy
12.1.4.5 Regulatory Status
12.1.5 BNT 111 - BioNTech
12.1.5.1 Drug Overview
12.1.5.2 Mechanism of Action
12.1.5.3 Clinical Trial Results
12.1.5.4 Safety and Efficacy
12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.
13. Advanced Melanoma - Attribute Analysis of Key Marketed and Pipeline Drugs
14. Advanced Melanoma - Clinical Trial Landscape
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 Advanced Melanoma - Market Scenario
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Advanced Melanoma - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Advanced Melanoma - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Advanced Melanoma - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Advanced Melanoma - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Advanced Melanoma - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Advanced Melanoma - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Advanced Melanoma - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Advanced Melanoma - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Advanced Melanoma - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Advanced Melanoma - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Advanced Melanoma - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Advanced Melanoma - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Advanced Melanoma - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Advanced Melanoma - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Advanced Melanoma - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Advanced Melanoma - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Advanced Melanoma - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Advanced Melanoma - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Advanced Melanoma - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Advanced Melanoma - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Advanced Melanoma - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Advanced Melanoma - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Advanced Melanoma - Access and Reimbursement Overview
16 Advanced Melanoma - Recent Events and Inputs From Key Opinion Leaders
17 Advanced Melanoma Market - SWOT Analysis
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 Advanced Melanoma Market - Strategic Recommendations19 Appendix

Methodology

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