The 7 major hepatic encephalopathy markets reached a value of US$ 1.7 Billion in 2023. Looking forward, the publisher expects the 7MM to reach US$ 2.9 Billion by 2034, exhibiting a growth rate (CAGR) of 6.11% during 2023-2034.
The hepatic encephalopathy market has been comprehensively analyzed in this report titled "Hepatic Encephalopathy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hepatic encephalopathy is a neurological condition that occurs as a result of liver dysfunction or failure. The liver plays a substantial role in removing waste products from the blood, and when it becomes impaired, these toxins can accumulate in the bloodstream and affect the brain. The most common indications associated with this disorder include irritability, mood swings, agitation, confusion, depression, memory loss, disorientation, sleep disturbances, slurred speech, poor coordination between movements, tremors, muscle stiffness, a sweet, musty odor on the breath, etc. Individuals suffering from the ailment may also experience yellowing of the eyes and skin due to the liver's impaired ability to process bilirubin. Hepatic encephalopathy is usually diagnosed based on clinical symptoms, neurological examination findings, and laboratory tests that show elevated ammonia levels in the blood. The healthcare professional may also perform several diagnostic procedures, like ultrasounds, computed tomography (CT) scans, magnetic resonance imaging, etc., to assess the structure and function of the liver as well as detect any irregularities that may be contributing to the underlying indications.
The increasing cases of liver tissue scarring due to chronic hepatitis B or C infection, excessive alcohol consumption, genetic and metabolic disorders, etc., are primarily driving the hepatic encephalopathy market. In addition to this, the rising incidences of portal hypertension, which causes blood to bypass the liver, leading to the accumulation of toxic substances in the bloodstream that can affect brain function, are creating a positive outlook for the market. Moreover, the widespread adoption of effective antibiotics, such as neomycin and rifaximin, to treat recurrent disease conditions is further acting as another significant growth-inducing factor. These therapeutic agents work by selectively suppressing the spread of harmful bacteria in the gut while preserving beneficial gut flora to alleviate the symptoms of the illness. Apart from this, the escalating application of ornithine phenylacetate therapy, since it stimulates the synthesis of glutamine in muscle tissue to aid in the removal of ammonia via alternative pathways, thereby stabilizing cognitive function and improving mental status in patients, is expected to drive the hepatic encephalopathy market during the forecast period.
This report provides an exhaustive analysis of the hepatic encephalopathy market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hepatic encephalopathy and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hepatic encephalopathy market in any manner.
The hepatic encephalopathy market has been comprehensively analyzed in this report titled "Hepatic Encephalopathy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hepatic encephalopathy is a neurological condition that occurs as a result of liver dysfunction or failure. The liver plays a substantial role in removing waste products from the blood, and when it becomes impaired, these toxins can accumulate in the bloodstream and affect the brain. The most common indications associated with this disorder include irritability, mood swings, agitation, confusion, depression, memory loss, disorientation, sleep disturbances, slurred speech, poor coordination between movements, tremors, muscle stiffness, a sweet, musty odor on the breath, etc. Individuals suffering from the ailment may also experience yellowing of the eyes and skin due to the liver's impaired ability to process bilirubin. Hepatic encephalopathy is usually diagnosed based on clinical symptoms, neurological examination findings, and laboratory tests that show elevated ammonia levels in the blood. The healthcare professional may also perform several diagnostic procedures, like ultrasounds, computed tomography (CT) scans, magnetic resonance imaging, etc., to assess the structure and function of the liver as well as detect any irregularities that may be contributing to the underlying indications.
The increasing cases of liver tissue scarring due to chronic hepatitis B or C infection, excessive alcohol consumption, genetic and metabolic disorders, etc., are primarily driving the hepatic encephalopathy market. In addition to this, the rising incidences of portal hypertension, which causes blood to bypass the liver, leading to the accumulation of toxic substances in the bloodstream that can affect brain function, are creating a positive outlook for the market. Moreover, the widespread adoption of effective antibiotics, such as neomycin and rifaximin, to treat recurrent disease conditions is further acting as another significant growth-inducing factor. These therapeutic agents work by selectively suppressing the spread of harmful bacteria in the gut while preserving beneficial gut flora to alleviate the symptoms of the illness. Apart from this, the escalating application of ornithine phenylacetate therapy, since it stimulates the synthesis of glutamine in muscle tissue to aid in the removal of ammonia via alternative pathways, thereby stabilizing cognitive function and improving mental status in patients, is expected to drive the hepatic encephalopathy market during the forecast period.
This report provides an exhaustive analysis of the hepatic encephalopathy market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hepatic encephalopathy and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hepatic encephalopathy market in any manner.
Time Period of the Study
- Base Year: 2023
- Historical Period: 2018-2023
- Market Forecast: 2024-2034
Countries Covered
- United States
- Germany
- France
- United Kingdom
- Italy
- Spain
- Japan
Analysis Covered Across Each Country
- Historical, current, and future epidemiology scenario
- Historical, current, and future performance of the hepatic encephalopathy market
- Historical, current, and future performance of various therapeutic categories in the market
- Sales of various drugs across the hepatic encephalopathy market
Competitive Landscape:
This report also provides a detailed analysis of the current hepatic encephalopathy marketed drugs and late-stage pipeline drugs.In-Market Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Key Questions Answered in this Report:
Market Insights
- How has the hepatic encephalopathy market performed so far and how will it perform in the coming years?
- What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
- What was the country-wise size of the hepatic encephalopathy market across the seven major markets in 2023 and what will it look like in 2034?
- What is the growth rate of the hepatic encephalopathy market across the seven major markets and what will be the expected growth over the next ten years?
- What are the key unmet needs in the market?
Epidemiology Insights
- What is the number of prevalent cases (2018-2034) of hepatic encephalopathy across the seven major markets?
- What is the number of prevalent cases (2018-2034) of hepatic encephalopathy by age across the seven major markets?
- What is the number of prevalent cases (2018-2034) of hepatic encephalopathy by gender across the seven major markets?
- How many patients are diagnosed (2018-2034) with hepatic encephalopathy across the seven major markets?
- What is the size of the hepatic encephalopathy patient pool (2018-2023) across the seven major markets?
- What would be the forecasted patient pool (2024-2034) across the seven major markets?
- What are the key factors driving the epidemiological trend of hepatic encephalopathy?
- What will be the growth rate of patients across the seven major markets?
Hepatic Encephalopathy: Current Treatment Scenario, Marketed Drugs and Emerging Therapies
- What are the current marketed drugs and what are their market performance?
- What are the key pipeline drugs and how are they expected to perform in the coming years?
- How safe are the current marketed drugs and what are their efficacies?
- How safe are the late-stage pipeline drugs and what are their efficacies?
- What are the current treatment guidelines for hepatic encephalopathy drugs across the seven major markets?
- Who are the key companies in the market and what are their market shares?
- What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the hepatic encephalopathy market?
- What are the key regulatory events related to the hepatic encephalopathy market?
- What is the structure of clinical trial landscape by status related to the hepatic encephalopathy market?
- What is the structure of clinical trial landscape by phase related to the hepatic encephalopathy market?
- What is the structure of clinical trial landscape by route of administration related to the hepatic encephalopathy market?
Table of Contents
1 Preface3 Executive Summary6 Patient Journey9 Hepatic Encephalopathy - Unmet Needs10 Hepatic Encephalopathy - Key Endpoints of Treatment13. Hepatic Encephalopathy - Attribute Analysis of Key Marketed and Pipeline Drugs16 Hepatic Encephalopathy - Recent Events and Inputs From Key Opinion Leaders18 Hepatic Encephalopathy Market - Strategic Recommendations19 Appendix
2 Scope and Methodology
4 Hepatic Encephalopathy - Introduction
5 Hepatic Encephalopathy - Disease Overview
7 Hepatic Encephalopathy - Epidemiology and Patient Population
8 Hepatic Encephalopathy - Treatment Algorithm, Guidelines, and Medical Practices
11 Hepatic Encephalopathy - Marketed Products
12 Hepatic Encephalopathy - Pipeline Drugs
14. Hepatic Encephalopathy - Clinical Trial Landscape
15 Hepatic Encephalopathy - Market Scenario
17 Hepatic Encephalopathy Market - SWOT Analysis
Methodology
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Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 139 |
| Published | May 2024 |
| Forecast Period | 2023 - 2034 |
| Estimated Market Value ( USD | $ 1.7 Billion |
| Forecasted Market Value ( USD | $ 2.9 Billion |
| Compound Annual Growth Rate | 5.0% |
| Regions Covered | Global |
