The 7 major PEComa markets are expected to exhibit a CAGR of 6.19% during 2023-2034.
The PEComa market has been comprehensively analyzed in this report titled "PEComa Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". PEComa, commonly referred to as, perivascular epithelioid cell tumor, is a rare form of mesenchymal neoplasm that originates from perivascular epithelioid cells, a unique group of tissues that exhibit both smooth muscle and melanocyte characteristics. This disease can develop in various organs, including the uterus, kidneys, lungs, and gastrointestinal tract. The symptoms of the ailment are often non-specific and vary depending on the location of the tumor. They may include pain, discomfort, or a palpable mass in the affected area. In some cases, PEComa can be asymptomatic and discovered incidentally during medical imaging for unrelated issues. The diagnosis of the illness involves a combination of clinical evaluation, imaging studies, such as CT scans or MRIs, and histopathological examination of a tissue biopsy. The characteristic histological findings include the presence of perivascular epithelioid cells with transparent to eosinophilic cytoplasm and centrally located round nuclei. Immunohistochemical staining is also recommended to confirm the diagnosis in patients.
The increasing incidences of aberrant gene mutations within the perivascular epithelioid cell group, resulting in uncontrolled tissue growth in various organs, are primarily driving the PEComa market. In addition to this, the inflating utilization of targeted therapeutic agents, such as mTOR inhibitors, tyrosine kinase inhibitors, and chemotherapy, to effectively manage and mitigate the condition's progression is also creating a positive outlook for the market. Moreover, the widespread adoption of personalized treatment approaches that capitalize on molecular profiling to tailor interventions based on the patient's genetic markers is further bolstering the market growth. Apart from this, the rising usage of complementary strategies, including supportive care and multidisciplinary therapeutic regimens, on account of their numerous benefits, like alleviated symptoms, enhanced quality of life, and optimized treatment outcomes, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of minimally invasive procedures, such as embolization and radiofrequency ablation, which are designed to precisely target and shrink PEComa tumors, is also augmenting the market growth. Furthermore, the escalating demand for gene editing techniques, particularly CRISPR-Cas9, since they offer the possibility to correct or modify the genetic anomalies responsible for the disorder, is expected to drive the PEComa market during the forecast period.
This report provides an exhaustive analysis of the PEComa market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for PEComa and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the PEComa market in any manner.
The PEComa market has been comprehensively analyzed in this report titled "PEComa Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". PEComa, commonly referred to as, perivascular epithelioid cell tumor, is a rare form of mesenchymal neoplasm that originates from perivascular epithelioid cells, a unique group of tissues that exhibit both smooth muscle and melanocyte characteristics. This disease can develop in various organs, including the uterus, kidneys, lungs, and gastrointestinal tract. The symptoms of the ailment are often non-specific and vary depending on the location of the tumor. They may include pain, discomfort, or a palpable mass in the affected area. In some cases, PEComa can be asymptomatic and discovered incidentally during medical imaging for unrelated issues. The diagnosis of the illness involves a combination of clinical evaluation, imaging studies, such as CT scans or MRIs, and histopathological examination of a tissue biopsy. The characteristic histological findings include the presence of perivascular epithelioid cells with transparent to eosinophilic cytoplasm and centrally located round nuclei. Immunohistochemical staining is also recommended to confirm the diagnosis in patients.
The increasing incidences of aberrant gene mutations within the perivascular epithelioid cell group, resulting in uncontrolled tissue growth in various organs, are primarily driving the PEComa market. In addition to this, the inflating utilization of targeted therapeutic agents, such as mTOR inhibitors, tyrosine kinase inhibitors, and chemotherapy, to effectively manage and mitigate the condition's progression is also creating a positive outlook for the market. Moreover, the widespread adoption of personalized treatment approaches that capitalize on molecular profiling to tailor interventions based on the patient's genetic markers is further bolstering the market growth. Apart from this, the rising usage of complementary strategies, including supportive care and multidisciplinary therapeutic regimens, on account of their numerous benefits, like alleviated symptoms, enhanced quality of life, and optimized treatment outcomes, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of minimally invasive procedures, such as embolization and radiofrequency ablation, which are designed to precisely target and shrink PEComa tumors, is also augmenting the market growth. Furthermore, the escalating demand for gene editing techniques, particularly CRISPR-Cas9, since they offer the possibility to correct or modify the genetic anomalies responsible for the disorder, is expected to drive the PEComa market during the forecast period.
This report provides an exhaustive analysis of the PEComa market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for PEComa and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the PEComa market in any manner.
Time Period of the Study
- Base Year: 2023
- Historical Period: 2018-2023
- Market Forecast: 2024-2034
Countries Covered
- United States
- Germany
- France
- United Kingdom
- Italy
- Spain
- Japan
Analysis Covered Across Each Country
- Historical, current, and future epidemiology scenario
- Historical, current, and future performance of the PEComa market
- Historical, current, and future performance of various therapeutic categories in the market
- Sales of various drugs across the PEComa market
Competitive Landscape:
This report also provides a detailed analysis of the current PEComa marketed drugs and late-stage pipeline drugs.In-Market Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Key Questions Answered in this Report:
Market Insights
- How has the PEComa market performed so far and how will it perform in the coming years?
- What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
- What was the country-wise size of the PEComa market across the seven major markets in 2023 and what will it look like in 2034?
- What is the growth rate of the PEComa market across the seven major markets and what will be the expected growth over the next ten years?
- What are the key unmet needs in the market?
Epidemiology Insights
- What is the number of prevalent cases (2018-2034) of PEComa across the seven major markets?
- What is the number of prevalent cases (2018-2034) of PEComa by age across the seven major markets?
- What is the number of prevalent cases (2018-2034) of PEComa by gender across the seven major markets?
- How many patients are diagnosed (2018-2034) with PEComa across the seven major markets?
- What is the size of the PEComa patient pool (2018-2023) across the seven major markets?
- What would be the forecasted patient pool (2024-2034) across the seven major markets?
- What are the key factors driving the epidemiological trend of PEComa?
- What will be the growth rate of patients across the seven major markets?
PEComa: Current Treatment Scenario, Marketed Drugs and Emerging Therapies
- What are the current marketed drugs and what are their market performance?
- What are the key pipeline drugs and how are they expected to perform in the coming years?
- How safe are the current marketed drugs and what are their efficacies?
- How safe are the late-stage pipeline drugs and what are their efficacies?
- What are the current treatment guidelines for PEComa drugs across the seven major markets?
- Who are the key companies in the market and what are their market shares?
- What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the PEComa market?
- What are the key regulatory events related to the PEComa market?
- What is the structure of clinical trial landscape by status related to the PEComa market?
- What is the structure of clinical trial landscape by phase related to the PEComa market?
- What is the structure of clinical trial landscape by route of administration related to the PEComa market?
Table of Contents
?1 Preface3 Executive Summary6 Patient Journey9 PEComa - Unmet Needs10 PEComa - Key Endpoints of Treatment13. PEComa - Attribute Analysis of Key Marketed and Pipeline Drugs16 PEComa - Recent Events and Inputs From Key Opinion Leaders18 PEComa Market - Strategic Recommendations19 Appendix
2 Scope and Methodology
4 PEComa - Introduction
5 PEComa - Disease Overview
7 PEComa - Epidemiology and Patient Population
8 PEComa - Treatment Algorithm, Guidelines, and Medical Practices
11 PEComa - Marketed Products
12 PEComa - Pipeline Drugs
14. PEComa - Clinical Trial Landscape
15 PEComa - Market Scenario
17 PEComa Market - SWOT Analysis
Methodology
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