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Bronchiectasis: Opportunity Assessment and Forecast

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    Report

  • 75 Pages
  • May 2024
  • Region: Global
  • GlobalData
  • ID: 5973272

This report covers the 8MM (US, France, Germany, Italy, Spain, UK, Japan, China) and provides an Excel-based forecast model for the bronchiectasis market through 2033.

Bronchiectasis, which has been given diagnostic code of J47.9 from the International Classification of Diseases, Tenth Edition (ICD-10), is defined by damage to the bronchi, causing abnormal dilation and scarring. The airways become inflamed with thick mucus that is difficult to clear, which build-up creates an environment for bacterial growth; uncontrolled bacterial growth leads to frequent infections. The cycle of repeated infections can in turn cause further damage to the airways. Bronchiectasis can occur throughout the lung or in a single section of lung.

Bronchiectasis is split into two main types: cystic fibrosis (CF), a genetically inherited disorder affecting the lungs, and non-CF bronchiectasis. Individuals who have CF can have lung symptoms similar to those of bronchiectasis, but for the purposes of this report, only non-CF bronchiectasis will be discussed. Some patients are symptom-free in everyday life and become clinically conspicuous only during exacerbations. Symptoms include excessive coughing (can be dry or productive, although productive cough is more common, especially in more severe/advanced disease), sputum production, recurrent chest infections, malaise, chest discomfort, hemoptysis, and weight loss.

Bronchiectasis is still relatively poorly understood; increasing emphasis has been placed on the role of underlying factors, such as the presence of comorbidities, but the development of bronchiectasis is multifactorial. Contributing factors include infections, immunodeficiency, impaired mucociliary clearance, previous lung injury, airway lesions, concurrent chronic respiratory diseases, and connective tissue and/or autoimmune diseases (Chalmers et al., 2018). There are no therapies marketed for the treatment of bronchiectasis, so there is a high demand due to the large unmet need

The publisher projects the global bronchiectasis marketplace - which, for the purposes of this report, comprises eight major pharmaceutical markets (US, France, Germany, Italy, Spain, UK, Japan, China) - to experience a significant growth during the forecast period. This growth will be driven primarily by the increase in the diagnosed cases, as well as by the global launch of Insmed's dipeptidyl peptidase-1 (DPP-1) inhibitor brensocatib, subject to approval. Nevertheless, drug-class preference by patients and physicians, are expected to curtail market growth, as the current management of bronchiectasis relies on generic off-label therapies.

This model covers the market forecast for marketed and late-stage pipeline for insomnia treatment. The base year of this model is 2023, and the forecast period is 2023-2033.

Key Highlights

  • Report deliverables include a PDF report and Excel-based forecast model
  • Forecasts includes the 8MM
  • Forecasts covers from 2023-2033

Scope

  • Overview of bronchiectasis, including epidemiology, symptoms, diagnosis, and disease management.
  • Annualized bronchiectasis treatment market revenue, cost of therapy per patient, and treatment usage patterns forecast from 2023 to 2033.
  • Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, and implications of these factors for the bronchiectasis therapeutics market.
  • Pipeline analysis: comprehensive data assessing emerging trends and mechanisms of action under development for bronchiectasis treatment. The most promising candidates in Phase III and Phase IIb development are profiled.
  • Analysis of the current and future market competition in the global bronchiectasis therapeutics market. Insightful review of the key industry drivers, restraints, and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipelines. 
  • Develop business strategies by understanding the trends shaping and driving the global bronchiectasis therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global bronchiectasis therapeutics market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

Table of Contents

1. Preface
1.1. Contents
1.2. Abbreviations
1.3. Related Reports
2. Executive Summary
3. Disease Overview
3.1. Overview of Bronchiectasis
3.2. Bronchiectasis SWOT Analysis
3.3. Pathophysiology of Bronchiectasis
3.4. Classification of Bronchiectasis
4. Epidemiology
4.1. Total Prevalent Cases of Bronchiectasis, Both Sexes, Ages =18 Years, 2023-33
4.2. Total Prevalent Cases of Bronchiectasis, Both Sexes, Ages =18 Years, 2023-33
4.3. Age-Specific Trends in Diagnosed Prevalent Cases of Bronchiectasis, Both Sexes, 2023
4.4. Sex-Specific Diagnosed Prevalent Cases of Bronchiectasis, Both Sexes, Ages =18 Years, 2023
4.5. Diagnosed Prevalent Cases of Bronchiectasis By Severity, Both Sexes, Ages =18 Years, 2023
4.6. Sources and Methodology for Diagnosed Prevalence of Bronchiectasis
5. Current Treatment Options
5.1. Treatment Paradigm
5.2. Marketed Products
5.3. Product Profile: Antibiotics (Oral, IV, Inhaled)
5.4. Product Profile: Bronchitol
5.5. Product Profile: Hypertonic Saline
5.6. Product Profile: Mucolytics
5.7. Product Profile: Bronchodilators
5.8. Product Profile: Asthma Biologics
5.9. Product Profile: Inhaled Steroids
6. Unmet Needs and Opportunities
6.1. Unmet Needs in Bronchiectasis
6.2. Increased Awareness and Education
6.3. Improved Diagnostic Methods
6.4. Lack of Approved Therapies
6.5. Targets for Improved Therapies
7. R&D Strategies
7.1. Trends in Clinical Trial Design in Bronchiectasis
7.2. Trends in Deal-Making in Bronchiectasis
8. Pipeline Assessment
8.1. Bronchiectasis Pipeline Overview
8.2. Late-Stage Pipeline Agents for Bronchiectasis
8.3. Product Profile: Insmed’s Brensocatib
8.4. Bronchiectasis: Clinical Trials - Phase II and Phase III Overview
9. Market Outlook
9.1. Bronchiectasis Market Forecast
9.2. Market Drivers and Barriers
10. Appendix
10.1. Primary Research: KOL Information
10.2. Bibliography
10.3. About the Authors
11. Contact the Publisher

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Insmed
  • Joincare
  • Renovion
  • Sanofi
  • Regeneron
  • Armata
  • Boehringer Ingelheim
  • Chiesi Farmaceutici
  • Haisco Pharmaceutical
  • Metagone Biotech
  • SolAeroMed
  • Suzhou Regend Therapeutics
  • CSL
  • BioAegis Therapeutics
  • AstraZeneca
  • Reistone Biopharma
  • Shanghai Fosun Pharmaceutical (Group) Co Ltd