The global protein expression market size was valued at USD 3 billion in 2023, driven by advancements in CRISPR technology globally. The market is expected to grow at a CAGR of 5.40% during the forecast period of 2024-2032, with the values likely to rise from USD 3.2 billion in 2024 to USD 4.9 billion by 2032.
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Global Protein Expression Market Analysis
The global protein expression market has seen substantial evolution from 2017 to 2032, influenced by a convergence of scientific advancements, expanding demands in biotechnology and pharmaceutical research, and the growing need for therapeutic protein production. These elements have been pivotal in shaping market dynamics, fostering innovation, and expanding the application range of protein expression technologies. The following are the key trends and developments observed in this market over the specified period.Global Protein Expression Market Trends
The global protein expression market from 2017 to 2032 has been marked by several significant trends that reflect the evolving landscape of biotechnology, pharmaceuticals, and academic research. These trends highlight the dynamic nature of the market, driven by technological advancements, growing demand across various applications, and strategic shifts in global healthcare and biopharmaceutical industries. Below are the key market trends observed during this period:Technological Advancements in Expression Systems: One of the most significant trends is the rapid advancement in protein expression technologies. Innovations have spanned across different expression systems, including bacterial, yeast, mammalian, and insect cells, with each system being optimized for higher yields, better protein quality, and greater cost-effectiveness. These technological improvements have enabled more efficient production of recombinant proteins, antibodies, vaccines, and therapeutics, catering to the increasing demands of research and development in life sciences.
- Rising Demand for Therapeutic Proteins: The protein expression market has been significantly impacted by the soaring demand for therapeutic proteins. This is largely due to the global increase in the prevalence of chronic diseases, such as cancer, diabetes, and autoimmune disorders, which has spurred the need for biologics, including monoclonal antibodies, hormones, and enzymes. The push towards personalized medicine has further amplified this demand, positioning protein expression as a critical component in the development and manufacturing of biopharmaceuticals.
- Expansion into Emerging Markets: The period has also seen the protein expression market expand its footprint into emerging markets, especially in Asia-Pacific and Latin America. These regions have witnessed rapid growth due to improvements in healthcare infrastructure, increased investments in biotechnology, and supportive government policies. The expanding research and development activities, coupled with a growing biopharmaceutical sector in these regions, have opened new avenues for market growth.
- Integration of Synthetic Biology and CRISPR Technologies: The integration of synthetic biology and CRISPR/Cas9 gene-editing technologies into protein expression practices have emerged as a transformative trend. These technologies have facilitated the development of novel protein variants, optimized expression vectors, and customized cell lines, thereby broadening the applications of protein expression in research, therapeutics, and industrial biotechnology.
- Focus on High-throughput and Automated Systems: With the increasing complexity and scale of protein production, there has been a marked shift towards high-throughput and automated protein expression systems. These systems offer enhanced efficiency, scalability, and reproducibility, meeting the needs of large-scale protein production for therapeutic and industrial applications. Automation has also played a crucial role in streamlining workflows, reducing labor costs, and improving overall productivity in protein expression operations.
- Regulatory and Quality Assurance Considerations: The regulatory landscape for biopharmaceutical products has become increasingly stringent, impacting the protein expression market. Compliance with Good Manufacturing Practices (GMP), regulatory approvals, and quality assurance standards have become paramount, especially for therapeutic protein production. This trend has necessitated the adoption of advanced expression systems and purification technologies that ensure high-quality protein products, suitable for clinical and commercial use.
- Custom and Contract Expression Services: The growth of custom and contract protein expression services represents another key trend, driven by the specialized needs of pharmaceutical and biotech companies, as well as academic institutions. Outsourcing protein expression projects to specialized service providers has allowed organizations to leverage expert knowledge, advanced technologies, and cost-effective solutions without significant in-house investments, fostering collaborations and accelerating the pace of research and development.
Global Protein Expression Market Segmentation
Market Breakup by Type of Expression System
- Bacterial Expression Systems
- Mammalian Expression Systems
- Yeast Expression Systems
- Insect Expression Systems
- Cell-Free Expression Systems
- Algal Expression Systems
- Other Expression Systems
Market Breakup by Product Type
- Reagents
- Expression Vectors
- Competent Cells
- Instruments
- Services
Market Breakup by Application
- Therapeutic Proteins
- Research Applications
- Industrial Proteins
- Diagnostic Proteins
- Others
Market Breakup by Technique
- Ion Exchange Chromatography
- Hydrophobic Interaction Chromatography (HIC)
- Affinity Chromatography
- Size Exclusion Chromatography
- Others
Market Breakup by Cell Type
- Mammalian Cells
- Bacterial Cells
- Yeast Cells
- Insect Cells
- Algal Cells
- Cell-Free Systems
Market Breakup by End User
- Biotechnology and Pharmaceutical Companies
- Academic Research Institutes
- Contract Research Organizations (CROs)
- Others
Market Breakup by Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
Global Protein Expression Market Competitive Landscape
The global protein expression market is highly competitive and fragmented, with the presence of several major players and numerous smaller ones. Key players involved in the market are Thermo Fisher Scientific, Inc., Merck KGaA (Sigma-Aldrich Corporation), Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., QIAGEN N.V., Lonza Group AG, Genscript Biotech Corporation, Takara Bio Inc., Promega Corporation, New England Biolabs, Oxford Expression Technologies Ltd. (OET), Synthetic Genomics, Inc., Biomatik Corporation, Cayman Chemical Company, and Zymo Research Corporation. These companies compete on various factors, such as product quality, innovation, pricing, customer service, distribution network, and geographical reach. They also engage in strategic partnerships, mergers and acquisitions, product launches, and expansion activities to strengthen their market position and expand their product portfolio.Key Questions Answered in This Report
- How has the protein expression market performed so far, and how will it perform in the coming years?
- What are the drivers, restraints, and opportunities in the protein expression market?
- What is the impact of each driver, restraint, and opportunity in the market?
- What are the key regional markets?
- Which major technological advancement has increased the potential of protein expression systems in synthetic biology?
- Which countries represent the most attractive market?
- What are market segmentations based on cell type?
- What is the breakup of the market based on the diagnosis?
- What is the competitive structure of the market?
- Who are the major players/companies dominating the market?
Key Benefits for Stakeholders
- The industry report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the protein expression from 2017-2032.
- The research report provides the latest information on the market drivers, challenges, and opportunities in the global protein expression market.
- The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
- Porter's five forces analysis assists stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the protein expression industry and its attractiveness.
- The competitive landscape allows stakeholders to understand their competitive environment and provides insight into the current positions of key players in the market.
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Table of Contents
1 Preface
3 Global Protein Expression Market Overview
4 Global Protein Expression Market Landscape*
5 Global Protein Expression Market Dynamics
6 Global Protein Expression Market Segmentation (2017-2032)
7 North America Protein Expression Market (2017-2032)
8 Europe Protein Expression Market (2017-2032)
9 Asia Pacific Protein Expression Market (2017-2032)
10 Latin America Protein Expression Market (2017-2032)
11 Middle East and Africa Protein Expression Market (2017-2032)
12 Regulatory Framework
13 Patent Analysis
14 Grants Analysis
15 Funding and Investment Analysis
16 Partnership and Collaborations Analysis
17 Supplier Landscape
18 Global Protein Expression Market - Distribution Model (Additional Insight)
20 Company Competitiveness Analysis (Additional Insight)
21 Payment Methods (Additional Insight)
Companies Mentioned
- Thermo Fisher Scientific Inc.
- Merck KGaA (Sigma-Aldrich Corporation)
- Agilent Technologies Inc.
- Bio-Rad Laboratories Inc.
- QIAGEN N.V.
- Lonza Group AG
- Genscript Biotech Corporation
- Takara Bio Inc.
- Promega Corporation
- New England Biolabs
- Oxford Expression Technologies Ltd. (OET)
- Synthetic Genomics Inc.
- Biomatik Corporation
- Cayman Chemical Company
- Zymo Research Corporation
Methodology
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Table Information
Report Attribute | Details |
---|---|
No. of Pages | 140 |
Published | May 2024 |
Forecast Period | 2024 - 2032 |
Estimated Market Value ( USD | $ 3.2 Billion |
Forecasted Market Value ( USD | $ 4.9 Billion |
Compound Annual Growth Rate | 5.4% |
Regions Covered | Global |
No. of Companies Mentioned | 15 |