A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals.
Table of Contents
1. Unveiling the complexity of Alzheimer’s disease: Introduction and its pathophysiologySHABNAM SHABIR AND MAHENDRA P. SINGH
2. Microglia, mitochondria, and inflammatory events in neurotoxicity of Alzheimer’s disease
PRITI GUPTA AND T.S. GOPENATH
3. Biomarkers used in Alzheimer’s disease diagnosis
SHAILENDRA KUMAR MISHRA, HUNG-MING CHANG, AHMAD A. OBAID, AND SANDEEP KUMAR SINGH
4. Molecular and neuroimaging biomarkers in the diagnosis of Alzheimer’s disease
PAALKI SETHI, KRISHNA KUMAR SINGH, APARAJITA DASGUPTA AMIST, M.P. SINGH, JITENDRA KUMAR SINHA, AND SHAMPA GHOSH
5. The genetic basis of neurodegenerative disorders: Implications in Alzheimer’s disease
MD GULAM JILANI, MEHBOOB HOQUE, SHAMS TABREZ, AND SAFDAR ALI
6. Current status of prevention strategies adapted for Alzheimer’s disease
ABHINAV SINGH, PAALKI SETHI, SHAMPA GHOSH, KRISHNA KUMAR SINGH, SACHIN ROHATGI, PRAVEEN SINGH, AND JITENDRA KUMAR SINHA
7. Treatment strategies used for Alzheimer’s disease
KOYEL KAR
8. Cerebrovascular pathology and targets for the prevention of Alzheimer’s disease
POONAM SHEORAN, RAHUL DEV TRIPATHI, SHAILENDRA KUMAR MISHRA, TANMOY GHATAK, AND SANDEEP KUMAR SINGH
9. Is the controversy between Baptists and Taoists still present?
ANISHA BHOLA, KAMEEV SHARMA, SHAMPA GHOSH, KRISHNA KUMAR SINGH, RAKESH BHASKAR, AND JITENDRA KUMAR SINHA
10. Nutraceuticals in the prevention and treatment of Alzheimer’s disease
DEVESH KUMAR MISHRA, SHAILENDRA KUMAR MISHRA, AMIT ASTHANA, KHOLIS ABDURACHIM AUDAH, MAHENDRA P. SINGH, AND SANDEEP KUMAR SINGH
11. Physical exercise and lifestyle management: Preventive measures for Alzheimer’s disease
PRADEEP KUMAR MISHRA, SHAMPA GHOSH, KRISHNA KUMAR SINGH, AND JITENDRA KUMAR SINHA
12. Brain insulin resistance and deficiency in Alzheimer’s disease: Role in the pathophysiology and the potential pharmacological targets
OLUSEGUN ADEBAYO ADEOLUWA, IBIFIRI PRECIOUS JACK, OLUWAFERANMI JOSEPH ATOLAGBE, AND CHRISTOPHER OKABA
13. Different drugs used as therapeutic targets against AD till date
MANISHA NAHAR, AAMIR KHAN, RAVINA RAI, AND DEEPALI JAT
14. Future perspectives on the clinics of Alzheimer’s disease
PRADEEP KUMAR MISHRA, KRISHNA KUMAR SINGH, SHAMPA GHOSH, AND JITENDRA KUMAR SINHA
15. AD prevention strategies adapted till present
RAYEES AHMAD NAIK, MEHAK NASEER MIR, ROSHNI RAJPOOT, SONALIKA SINGH, KUSUM SINGH, AND SANDEEP KUMAR SINGH
Authors
Sandeep Kumar Singh Department of Medical Biotechnology, All India Institute of Medical Sciences, Nagpur, MH, India.Assistant Professor in Department of Medical Biotechnology at the All India Institute of Medical Sciences, Nagpur. He is researcher and neuroscientist with a strong background in Biochemistry and Biomedicine. His research interests are in neurodegenerative diseases and has ~12 years of experience. He's a member of editorial boards of several international journals related to neuroscience and member of several scientific societies. Dr. Singh has been appointed as Bentham Ambassador by Bentham Science Publisher (USA). He is a speaker at several scientific national and international conferences/symposium/workshops in India and abroad.
Ricardo Maccioni Laboratory of Neurosciences and Functional Medicine, International Center for Biomedicine and University of Chile, Chile. A Professor of Neurology at the University of Chile and Director and General of the International Center for Biomedicine. A world-class scientist, ranked in the top 1% of researchers in the world and widely recognized by his peers. His investigations allowed to open a new paradigm demonstrating the neuroinflammatory basis of Alzheimer�s disease (Theory of neuroimmunomodulation). This theory has allowed technologies to advance hand in hand with innovative tools that allowed him to generate an innovative biomarker that detect Alzheimers 10 years before its clinical phase.
