The extremely popular textbook Immunology & Serology in Laboratory Medicine, 8th Edition provides the foundation you need to master the relevant competencies demanded in today’s clinical laboratory. Immunology & Serology helps you gain the knowledge required by medical laboratory technician (MLT) and medical laboratory scientist (MLS) students to achieve excellent scores on national board certification upon graduation and to display entry-level professional competencies for career success. Featuring a straightforward presentation, each chapter in this edition presents state-of-the-art content in subject areas such as Molecular Diagnostics. A problem-based case study approach that stimulates critical thinking makes it easier to integrate the concepts of theory with laboratory procedures that generate diagnostic information in cases of infectious diseases, immune disorders, tumor immunology, and tissue transplantation. Immunology & Serology is a distinctly unique textbook because the author recognizes the importance of robust professional knowledge and the practice guidelines developed by the American Society for Clinical Pathology (ASCP) Board of Certification Examination Immunology Content Outlines for MLT and MLS certification levels and the American Society for Clinical Laboratory Science (ASCLS) Professional Body of Knowledge.
- NEW! Updated content includes the most current information related to infectious and immunological diseases, diagnostic testing methods, and vaccines.
- Clinical case studies include etiology, pathophysiology, laboratory findings, and critical thinking questions, allowing you to apply your knowledge of concepts and procedures.
- Visual learning features make studying easier with algorithms, illustrations, photographs, and summary boxes.
- Key Concepts are interwoven throughout each chapter, highlighting the most important facts.
- Content correlation between lecture and reading, diagnostic laboratory procedures, and case studies allows for easy reference.
- Learning objectives and key terms open each chapter, providing measurable outcomes and a framework for organizing your study efforts.
- More than 650 end-of-chapter, multiple-choice questions provide opportunities for review and self-assessment.
- Laboratory procedures on the Evolve website and in the eBook help you apply immunology and serology theory to clinical laboratory practice.
Table of Contents
PART I: Basic Immunologic Mechanisms1. Foundations of Immunology
2. Soluble Mediators of the Immune System
3. Antigens and Antibodies
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
PART II: The Theory of Immunologic and Serologic Procedures
5. Safety in the Immunology-Serology Laboratory
6. Quality Control and Quality Assurance Practices
7. Serologic Laboratory: Techniques and Clinical Applications
8. Precipitation and Particle Agglutination Methods
9. Electrophoresis Techniques and Chromatography
10. Labeling Techniques in Immunoassay
11. Flow Cytometry
12. Molecular Laboratory Techniques
PART III: Immunologic Manifestations of Infectious Diseases
13. Infectious Diseases: Overview & TORCH Diseases
14. Streptococcal Infections
15. Syphilis
16. Vector-Borne Diseases
17. Infectious Mononucleosis
18. Viral Hepatitis
PART IV: Immune Disorders
19. Primary and Acquired Immunodeficiency Syndromes
20. Hypersensitivity Reactions
21. Plasma Cell Neoplasms and Other Diseases with Paraproteins
22. Tolerance, Autoimmunity, and Autoimmune Disorders
23. Systemic Lupus Erythematosus
24. Rheumatoid Arthritis
PART V: Transplantation & Tumor Immunology
25. Transplantation: Human Leukocyte Antigens, Solid Organ, and Hematopoietic Stem Cells,
26. Tumor Immunology and Applications of Massive Parallel Sequencing/Next-Generation Sequencing
PART VI: Vaccines
27. Vaccines-Development and Applications
Appendix A: Answers to Case Study Multiple-Choice Questions
Appendix B: Answers to Review Questions
Appendix C: Origin and Immunoregulatory Activity of Cytokines
Appendix D: Coronavirus Disease 2019 (COVID-19)
Appendix E: Vaccines Licensed in the United States by the Federal Drug Administration
Bibliography
Glossary
Authors
Mary Louise Turgeon Associate Professor (Adjunct), University of Texas Medical Branch, Galveston, Texas; Clinical Laboratory Education Consultant, Mary L. Turgeon and Associates, Boston, Massachusetts; St. Petersburg, Florida. Mary Louise Turgeon, EdD, MLS(ASCP)CM, is an educator, author, and consultant in medical laboratory science education. Her career includes roles as a community college professor, Medical Laboratory Technology program director, undergraduate and graduate university professor, Medical Laboratory Science program director, and departmental chairperson. Dr. Turgeon is currently an ad hoc educational content specialist for the College of Professional Studies, Northeastern University, Boston,and maintains an active clinical laboratory science consulting practice. Her practice, Mary L. Turgeon and Associates, focuses on new program development, curriculum revision, and increasing teaching effectiveness
through the use of technology and interactive teaching strategies.