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Fetal Metabolic Programming in Obesity and Diabetes. From Mechanisms to Preventive Therapy. Hot Topics in Physiology

  • Book

  • January 2025
  • Elsevier Science and Technology
  • ID: 5986995
Fetal Metabolic Programming in Obesity and Diabetes: From Mechanisms to Preventive Therapy describes the consequences of cellular and molecular aspects of maternal obesity (before and during pregnancy), diabetes mellitus (pregestational and gestational), and gestational diabesity (i.e., women with pre-pregnancy obesity that developed GDM). The book covers the clinical aspects of mothers and children and the protocols for treating these diseases during pregnancy. Since the patients' clinical information correlates with metabolic parameters at a cellular and systemic level, it covers several pieces of evidence, addressing the pathophysiology of obesity and diabetes in pregnancy.

This is an important resource for health professionals, researchers, and postdocs in obesity diabetes, as well as public health, physiology, biochemistry, cell biology, cell physiology, cell metabolism, and clinical medicine.

Table of Contents

1. Beta cells and in uterus programming
2. Pre-pregnancy obesity and programming of child diseases
3. Modifiable perinatal influences on child obesity
4. Extracellular vesicles and programming of metabolic diseases
5. Obesity and diabetes programming
6. Obesity and sex programming
7. Nutrition in pregnancy and programming of gestational diabetes
8. Postpartum cardiometabolic risk and gestational diabetes mellitus
9. Developmental programming of obesity
10. Diabetes and programming
11. Perinatology
12. Epigenetics and programming

Authors

Luis Sobrevia Division of Obstetrics and Gynecology, Faculty of Medicine, Pontificia Universidad Cat�lica de Chile, Chile. Luis Sobrevia, Director of the Cellular and Molecular Physiology Laboratory (CMPL) at PUC is a Fellow of The Physiological Society (UK) (FTPS), a Fellow of the Academy of Physiology of the International Union of Physiological Sciences (FIUPS), member of the Academy of Sciences of Latin-America (ACAL), Professor of Molecular Physiology and Medicine at the Faculty of Medicine at PUC, Honorary Professor at University of Queensland (Australia), Universidad de Sevilla (Spain), and S�o Paulo State University (UNESP, Brazil), He is a Distinguished Research Professor at TecSalud, Tecnol�gico de Monterrey (Mexico), and Visiting Professor at the University of Groningen (The Netherlands). He has 236 publications in reputed journals (Google h-index = 53, WoS h-index = 40), tutored 69 graduate theses and 20 postdoctoral (by Sep 26, 2022). His The research focus is altered fetoplacental vascular function in diseases of pregnancy, gestational diabesity, gestational diabetes mellitus, preeclampsia, and maternal obesity.