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Trichomonas Vaginalis. Pathogenesis, Diagnosis, and Treatment

  • Book

  • January 2025
  • Elsevier Science and Technology
  • ID: 5987003

Trichomonas Vaginalis: Pathogenesis, Diagnosis, and Treatment provides up-to-date knowledge about Trichomoniasis, the most prevalent and neglected non-viral sexually transmitted infection that can result in compromised reproductive health. The book discusses its epidemiology, the pathogenesis of disease, the mechanisms involved in the host immune response, clinical manifestations, and its impact on reproductive health. In addition, it also describes the new insights and challenges involved in the identification of promising drug targets and examines current diagnostic tools and therapies against Trichomonas vaginalis infection. In summary, the book provides comprehensive coverage of this neglected protozoan parasite and the sexually transmitted infection it causes. It is a valuable resource to researchers and scientists who are working on male and female reproductive disorders caused by Trichomonas vaginalis.

Table of Contents

1. T. vaginalis: a Neglected Sexually Transmitted Infection
2. Structure, Morphology, and Global Epidemiology of T. vaginalis
3. Virulence factors and pathogenesis of T. vaginalis
4. Different In-Vivo and In-Vitro Experimental Models For T. vaginalis Research
5. Trichomonas Vaginalis and Female Reproductive Tract Microbiota
6. T. vaginalis Infection and Female Reproductive Health
7. T. vaginalis Infection and Male Reproductive Health
8. Immunological Aspects of Tricomoniasis
9. Drug Resistance Mechanisms in T. vaginalis
10. Immunology and Pathogenesis of T. Vaginalis and HIV Coinfection
11. T. vaginalis and its Correlation with Other Sexually Transmitted Infections
12. Recent Advances in Diagnosis of T. vaginalis Infections
13. Different Strategies for Treatment and Management of Trichomoniasis
14. Molecular Targets for T. vaginalis
15. T. vaginalis Research Future Directions Opportunities and Challenges

Authors

Prashant Khare Director (R&D), Center for Advanced Biotechnology Research Absolute Foods, Gurugram, Haryana, India. Dr. Prashant Khare is a Vice President (R&D) at Xenesis Institute, Absolute in Gurugram (Haryana), India. Previously, he was a Ramalingaswami Fellow and Scientist D in the Department of Microbiology at the All India Institute of Medical Sciences, Bhopal, India. He completed his PhD from the Division of Parasitology at the Central Drug Research Institute in Lucknow, (Uttar Pradesh), India. He has almost five years of postdoctoral experience from the Baylor Institute for Immunology Research and UT Southwestern Medical Center in Dallas, Texas, USA, and more than 15 years of research experience in the field of infectious biology, immunology, vaccine, and drug development. He has published more than 30 research papers in highly reputable international journals such as Nature Immunology and Nature Communication. He has reviewed publications and served in an editorial role for several international journals as well. Ashish Jain Assistant Professor, Department of Microbiology, Smt. CHM College Ulhasnagar, Mumbai, India. Dr. Ashish Jain is working as an Assistant Professor (senior scale) since last eleven years in the Department of Microbiology, Smt. CHM College Ulhasnagar; affiliated with the University of Mumbai (Maharashtra), India. He has completed his PhD from Division of Endocrinology, Central Drug Research Institute, Lucknow (Uttar Pradesh) India on spermicides and anti-Trichomonas molecules and their mode of action. He has published more than 20 reputed international research papers and reference books in the field of Sexually transmitted infections and reproductive biology and credited international patents in his account. He is a recognized postgraduate teacher and PhD guide of University of Mumbai in Microbiology subject. Presently he is working to investigate the role of vaginal microbiota on reproductive health.