Primer on Cerebrovascular Research provides both clinical and basic cerebrovascular knowledge that is required for physicians, vascular researchers, biomedical students, and trainees to understand or conduct evidence-based clinical practice and cutting-edge experimental research. This book outlines how to a design experimental cerebrovascular research in the context of clinical relevance, conduct the study using proper methods, analyze the data accurately, and make conclusions in an unbiased and statistically correct way. Chapters will include representative examples and experimental protocols.
Table of Contents
1. A Brief History of Cerebrovascular Research 2. Clinical Knowledge for Basic / Translational Cerebrovascular Researchers 3. Running Statistics 4. Designing and Interpreting Cerebrovascular Research 5. Cerebrovascular Research Protocols and Troubleshooting 6. Latest Research in Cerebrovascular Diseases 7. Emerging Technologies for Cerebrovascular Research 8. Financial and Business Skills Needed for Translational Research
Authors
Dong-Eog Kim Department of Neurology, Dongguk University Ilsan Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Dong-Eog Kim graduated from Seoul National University College of Medicine, South Korea. He received MS and PhD in Neuroscience at Seoul National University Graduate School of Medicine. After finishing his neurology residency and stroke fellowship at Seoul National University Hospital, he worked for three years as a basic research fellow of Center for Molecular Imaging Research (now, Center for Systems Biology) at Massachusetts General Hospital, Harvard Medical School. He is a professor of Neurology and director of Biomedical Research Center at Dongguk University Ilsan Hospital. He is director of Molecular Imaging & Neurovascular Research Laboratory. He is director of Korean Brain MRI data center and National Priority Research Center for Stroke, designated by Korean government. He has published 178 peer-reviewed articles in peer-reviewed journals, mostly in highly regarded journals such as Circulation, JAMA Neurology, PLOS Medicine, Annals of Neurology, Neurology, and Stroke. He also wrote many book chapters and books.
Alastair Buchan Professor of Stroke Medicine, University of Oxford, Radcliffe Department of Medicine, University of Oxford, Headington, Oxford, UK.
Alastair Buchan is a translational stroke expert, whose science contributions include molecular biology, in vivo stroke models, clinical trials, and quantitative imaging (1-2 refs). He developed the ASPECTS score which is used world-wide today.
Eng H. Lo Professor of Neurology and Radiology, Harvard Medical School, Research Staff, Mass General Hospital, Massachusetts General Hospital, Neuroprotection Research Lab, Charlestown, MA, USA.
Eng H. Lo is a basic neurovascular scientist. He helped develop the neurovascular unit concept (Lo, Nat Rev Neurosci 2003; Tiedt et al, Nat Rev Neurol 2022).
Jeffrey L. Saver Professor, Neurology, UCLA, Ronald Reagan UCLA Medical Center, Los Angeles, CA, USA.
Jeffrey Saver is a world leader in stroke research and clinical trials (e.g. FAST-MAG, SWIFT-PRIME) (1-2 refs). He helped lay the foundations of trial design for neuroprotection and thrombectomy.
