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Fundamentals and Future Trends of 3D Printing in Drug Delivery

  • Book

  • January 2025
  • Elsevier Science and Technology
  • ID: 5987013

Fundamentals and Future Trends of 3D Printing in Drug Delivery provides readers with all needed information for their journey from ideation to approval of innovative drug delivery devices produced through additive manufacturing. This book provides an in-depth discussion on key factors affecting the printing process such as different printer technologies, materials selection, resolutions, temperatures and speeds. Dedicated chapters include specific drug delivery devices in the form of oral solid dosage, implants, catheters and vascular grafts, and microneedles. The prospects of 3D printing associated with personalized medicine are covered in a full chapter. Fundamentals and Future Trends of 3D Printing in Drug Delivery is the perfect reference for any researcher or professional embarking on a 3D printing process for drug delivery devices. The regulatory aspects included are of particular interest to companies entering this promising market.

Table of Contents

1. An overview of emerging applications of 2D, 3D, 4D, 5D and 6D Printing in drug delivery
2. 3D printing Technologies for pharmaceutical applications
3. Polymeric biomaterials for 3D printing
4. Design Optimization and Finite Element Analysis of 3D Printed Systems
5. 3D Printing in Personalized Medicine
6. 3D Printing of pharmaceutical oral solid dosage forms
7. 3D Printed personalized long-acting pharmaceutical Implants
8. Development of 3D printed drug loaded catheters & vascular grafts
9. 3D Printed Microneedle Patches for Painless Drug Delivery
10. 3D Printed therapeutic scaffolds for wound healing applications
11. 3D Printing in Oncology
12. 3D Printed gynecological implants
13. 3D printing in preclinical evaluation
14. 4D Printed therapeutic systems
15. Additive manufacturing and AI
16. Regulatory in 3D printing systems in healthcare

Authors

Dimitrios A. Lamprou Professor, School of Pharmacy, Material and Advanced Technologies for Healthcare, Queen's University Belfast, Northern Ireland, UK. Dr. Lamprou is Full Professor, Chair of Biofabrication and Advanced Manufacturing, and Director at MSc Industrial Pharmaceutics at Queen's University Belfast. He is also the Chair at United Kingdom and Ireland Controlled Release Society (UKICRS) and the Chair of the Academy of Pharmaceutical Sciences (APS) Emerging Technologies Focus Group. Dimitrios, is the author of over 140 peer-reviewed publications (including 3 books in 3D Printing area), has over 350 conference abstracts, has given over 150 Invited Talks in institutions and conferences across the world, and has secure Funding more than �3M. Dimitrios, has been recognized as world leader in 3D Printing with PubMed-based algorithms placed him in the top 0.088% of scholars in the world writing about 3D Printing in the last 10 years. Dimitrios has also been named in the Stanford University's list 2021 & 2022 of World's Top 2% Scientists, for his research in Pharmaceutics and Biomedical Engineering. Dimitros G Fatouros Professor, Department of Pharmacy, Aristotle University of Thessaloniki, Greece. Dimitris Fatouros is Professor in Pharmaceutics at Aristotle University of Thessaloniki School of Pharmacy. He holds a PhD in Pharmaceutical Technology from the School of Pharmacy at the University of Patras in Greece. He subsequently held posts as a Post-Doctoral fellow at Leiden/Amsterdam Centre of Drug Delivery (LA/CDR), Research Assistant Professor at Danish University of Pharmaceutical Sciences and Senior Lecturer at School of Pharmacy and Biomedical Portsmouth University. His areas of research expertise cover additive manufacturing, mucosal delivery, nanomedicine and poorly soluble drugs. He has contributed over 180 publications in refereed journals and books. He has filled three national (granted) and five international patents. He has been Theme Editor in Advanced Drug Delivery Reviews "Personalized nanomedicine� (Editors, Vizirianakis and Fatouros, ADDR 2012 64 :1359-62) and "Additive Manufacturing in Pharmaceutical Product Design� (Editors, Rantanen and Fatouros 2021 178:113991). He is Associate Editor in Journal of Drug Delivery Science and Technology (Elsevier), Associate Editor in Frontiers and Bioengineering and Biotechnology and member of the Editorial Board of Pharmaceutics.