The diagnosis and treatment of bone marrow pathologies is one of the most critical areas of medical research and care. For years, Bone Marrow Pathology has served as the essential reference and teaching tool in the field of haematology, with an authoritative treatment of the subject written by acknowledged leaders in the field. Now fully updated to reflect urgent new changes to the theory and practice of haematology, it promises to serve a new generation of practitioners.
In the book, the characteristics and function of normal bone marrow are extensively discussed. Bone marrow pathology, including both aspirate films and trephine biopsy sections, is examined in a clinical context. The content is augmented by discussion of the peripheral blood findings and supplementary bone marrow tests. Readers of the sixth edition of Bone Marrow Pathology will also find: - Lavish illustrations with high-quality images of bone marrow and other associated images- Incorporation of new classifications including the WHO and International Consensus classifications, as well as new and expanded research areas- Emphasis on practical tools including differential diagnosis and common problems and pitfalls- A practical, integrated approach to diagnosis
Perfect for trainee and consultant haematologists and haematopathologists, Bone Marrow Pathology will also prove itself invaluable for cytogeneticists, molecular geneticists and anyone working in immunophenotyping.
Table of Contents
Preface to the Sixth Edition vi
Acknowledgements vii
Abbreviations viii
1 The normal bone marrow: examining and reporting bone marrow specimens 1
2 Special techniques applicable to bone marrow diagnosis 63
3 Infection and reactive changes 115
4 Acute myeloid leukaemia mixed phenotype acute leukaemia the myelodysplastic neoplasms/syndromes and histiocytic and dendritic cell neoplasms 197
5 Myeloproliferative and myelodysplastic/myeloproliferative neoplasms and related conditions 276
6 Lymphoproliferative disorders 357
7 Plasma cell neoplasms and related conditions 507
8 Disorders of erythropoiesis granulopoiesis and thrombopoiesis 563
9 Miscellaneous disorders 613
10 Metastatic and non- haemopoietic tumours 675
11 Diseases of bone 716
Appendix 731
Index 742
