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Orthostatic Hypotension Drugs - Global Strategic Business Report

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    Report

  • 286 Pages
  • February 2025
  • Region: Global
  • Global Industry Analysts, Inc
  • ID: 5991198
The global market for Orthostatic Hypotension Drugs was valued at US$1.2 Billion in 2024 and is projected to reach US$1.8 Billion by 2030, growing at a CAGR of 7.7% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions.

Global Orthostatic Hypotension Drugs Market - Key Trends and Drivers Summarized

Orthostatic hypotension, also known as postural hypotension, is a condition characterized by a significant drop in blood pressure when a person stands up from sitting or lying down, leading to symptoms like dizziness, lightheadedness, or even fainting. This condition can be particularly prevalent in the elderly or in individuals with certain neurological disorders such as Parkinson’s disease. The treatment for orthostatic hypotension primarily aims to increase blood pressure and improve blood flow. Drugs commonly used for this condition include midodrine, which activates receptors on the smallest arteries and veins to increase vascular tone and blood pressure, and fludrocortisone, which enhances sodium retention to increase fluid volume in the circulatory system. Additionally, non-pharmacological strategies such as increased salt intake, wearing compression stockings, and physical maneuvers are often recommended alongside medication.

The development of drugs for orthostatic hypotension has been relatively moderate, focusing on symptomatic management rather than cure. However, recent advances in understanding the underlying pathophysiological mechanisms of the condition have opened up possibilities for targeted drug therapies. Researchers are exploring the roles of various neurotransmitters and hormonal pathways in regulating blood pressure and vascular tone. This has led to investigational therapies that aim to modulate these pathways more precisely, potentially offering more effective and sustainable treatment options. For example, novel agents that can enhance the responsiveness of the autonomic nervous system or improve cardiac output are under study. Additionally, there is growing interest in using combination therapies that address multiple mechanisms contributing to orthostatic hypotension, thus providing a more holistic approach to treatment.

The growth in the orthostatic hypotension drugs market is driven by several factors, including an aging global population, increased prevalence of diabetes and heart diseases, and improved diagnostic techniques that lead to higher detection rates of the condition. With the rise in elderly populations, who are more susceptible to orthostatic hypotension due to physiological changes and comorbid conditions, there is a corresponding increase in the demand for effective treatments. Furthermore, advancements in medical technologies and diagnostics are enabling better identification and understanding of various forms of blood pressure dysregulation, including orthostatic hypotension, leading to more targeted interventions. Consumer behavior also influences this market, as patients seek treatments that offer quick relief from symptoms and improve quality of life without significant side effects. The development of new drugs that can safely be combined with existing hypertension medications is also a critical area of research, driven by the need to manage orthostatic hypotension in patients with complex health profiles. Collectively, these drivers ensure ongoing investments and innovations in the development of orthostatic hypotension treatments.

Report Scope

The report analyzes the Orthostatic Hypotension Drugs market, presented in terms of market value (US$ Thousand). The analysis covers the key segments and geographic regions outlined below.

Segments

Drug Type (Midodrine Drug, Northera (Droxidopa) Drug, Fludrocortisone Drug, Other Drug Types); Diagnostic Test (ECG Test, Blood Test, Stress Test, Other Diagnostic Tests).

Geographic Regions/Countries

World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Key Insights:

  • Market Growth: Understand the significant growth trajectory of the Midodrine Drug segment, which is expected to reach US$943.3 Million by 2030 with a CAGR of a 9%. The Northera (Droxidopa) Drug segment is also set to grow at 7.1% CAGR over the analysis period.
  • Regional Analysis: Gain insights into the U.S. market, valued at $316 Million in 2024, and China, forecasted to grow at an impressive 12.4% CAGR to reach $416.8 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Report Features:

  • Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
  • In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
  • Company Profiles: Coverage of major players such as Alembic Pharmaceuticals, Inc., Avalo Therapeutics, Inc, Baxter International, Inc., CuraSen Therapeutics, H. Lundbeck A/S and more.
  • Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Why You Should Buy This Report:

  • Detailed Market Analysis: Access a thorough analysis of the Global Orthostatic Hypotension Drugs Market, covering all major geographic regions and market segments.
  • Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
  • Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Orthostatic Hypotension Drugs Market.
  • Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

  • How is the Global Orthostatic Hypotension Drugs Market expected to evolve by 2030?
  • What are the main drivers and restraints affecting the market?
  • Which market segments will grow the most over the forecast period?
  • How will market shares for different regions and segments change by 2030?
  • Who are the leading players in the market, and what are their prospects?

Some of the 43 major companies featured in this Orthostatic Hypotension Drugs market report include:

  • Alembic Pharmaceuticals, Inc.
  • Avalo Therapeutics, Inc
  • Baxter International, Inc.
  • CuraSen Therapeutics
  • H. Lundbeck A/S
  • Hikma Pharmaceuticals PLC
  • Luye Pharma Group
  • Manus Aktteva Biopharma LLP
  • Novartis AG
  • Pfizer Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Theravance Biopharma, Inc.
  • Upsher-Smith Laboratories LLC
  • Viatris
  • Zydus Lifesciences Limited

Table of Contents

I. METHODOLOGYII. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
  • Influencer Market Insights
  • World Market Trajectories
  • Global Economic Update
  • Orthostatic Hypotension Drugs - Global Key Competitors Percentage Market Share in 2025 (E)
  • Competitive Market Presence - Strong/Active/Niche/Trivial for Players Worldwide in 2025 (E)
2. FOCUS ON SELECT PLAYERS
3. MARKET TRENDS & DRIVERS
  • Rising Prevalence of Orthostatic Hypotension Drives Market Growth
  • Increasing Focus on Geriatric Healthcare Strengthens Business Case for Orthostatic Hypotension Drugs
  • Growing Awareness of Orthostatic Hypotension and Its Complications Expands Addressable Market Opportunity
  • Rising Demand for Alpha-Agonists and Mineralocorticoids Drives Market Dynamics
  • Increasing Adoption in Hospital and Ambulatory Care Settings Propels Market Growth
  • Expansion of Health Insurance Coverage Strengthens Market Adoption
  • Growing Trend of Home-Based and Long-Term Care Bodes Well for Market Expansion
  • Growth of the Aging Population Sets the Stage for Market Expansion
  • Increasing Use of Wearable Monitoring Devices Generates New Opportunities
4. GLOBAL MARKET PERSPECTIVE
  • Table 1: World Orthostatic Hypotension Drugs Market Analysis of Annual Sales in US$ Thousand for Years 2015 through 2030
  • Table 2: World Recent Past, Current & Future Analysis for Orthostatic Hypotension Drugs by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 3: World Historic Review for Orthostatic Hypotension Drugs by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 4: World 15-Year Perspective for Orthostatic Hypotension Drugs by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets for Years 2015, 2025 & 2030
  • Table 5: World Recent Past, Current & Future Analysis for Midodrine Drug by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 6: World Historic Review for Midodrine Drug by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 7: World 15-Year Perspective for Midodrine Drug by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • Table 8: World Recent Past, Current & Future Analysis for Northera (Droxidopa) Drug by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 9: World Historic Review for Northera (Droxidopa) Drug by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 10: World 15-Year Perspective for Northera (Droxidopa) Drug by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • Table 11: World Recent Past, Current & Future Analysis for Fludrocortisone Drug by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 12: World Historic Review for Fludrocortisone Drug by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 13: World 15-Year Perspective for Fludrocortisone Drug by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • Table 14: World Recent Past, Current & Future Analysis for Other Drug Types by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 15: World Historic Review for Other Drug Types by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 16: World 15-Year Perspective for Other Drug Types by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • Table 17: World Recent Past, Current & Future Analysis for ECG Test by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 18: World Historic Review for ECG Test by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 19: World 15-Year Perspective for ECG Test by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • Table 20: World Recent Past, Current & Future Analysis for Blood Test by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 21: World Historic Review for Blood Test by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 22: World 15-Year Perspective for Blood Test by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • Table 23: World Recent Past, Current & Future Analysis for Stress Test by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 24: World Historic Review for Stress Test by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 25: World 15-Year Perspective for Stress Test by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • Table 26: World Recent Past, Current & Future Analysis for Other Diagnostic Tests by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR
  • Table 27: World Historic Review for Other Diagnostic Tests by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2015 through 2023 and % CAGR
  • Table 28: World 15-Year Perspective for Other Diagnostic Tests by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
III. MARKET ANALYSIS
UNITED STATES
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2025 (E)
CANADA
JAPAN
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2025 (E)
CHINA
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2025 (E)
EUROPE
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2025 (E)
FRANCE
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2025 (E)
GERMANY
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2025 (E)
ITALY
UNITED KINGDOM
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2025 (E)
SPAINRUSSIAREST OF EUROPE
ASIA-PACIFIC
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2025 (E)
AUSTRALIA
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Australia for 2025 (E)
INDIA
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in India for 2025 (E)
SOUTH KOREAREST OF ASIA-PACIFIC
LATIN AMERICA
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Latin America for 2025 (E)
ARGENTINABRAZILMEXICOREST OF LATIN AMERICA
MIDDLE EAST
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Middle East for 2025 (E)
IRANISRAELSAUDI ARABIAUNITED ARAB EMIRATESREST OF MIDDLE EAST
AFRICA
  • Orthostatic Hypotension Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Africa for 2025 (E)
IV. COMPETITION

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Alembic Pharmaceuticals, Inc.
  • Avalo Therapeutics, Inc
  • Baxter International, Inc.
  • CuraSen Therapeutics
  • H. Lundbeck A/S
  • Hikma Pharmaceuticals PLC
  • Luye Pharma Group
  • Manus Aktteva Biopharma LLP
  • Novartis AG
  • Pfizer Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Theravance Biopharma, Inc.
  • Upsher-Smith Laboratories LLC
  • Viatris
  • Zydus Lifesciences Limited