Neuroendoscopy and Interventional Pain Medicine is a clinically focused medical monograph series. With contributions from a team of internationally recognized neurosurgeons and spinal surgery specialists, the series aims to illuminate the latest advancements in minimally invasive neurosurgical techniques and pain management. Each volume offers invaluable insights into the future of minimally invasive treatments in this medical subspecialty.
Interventional Pain Surgery is the third of the monograph series. This book comprehensively covers endoscopic techniques for spinal surgery. Topics include interlaminar lumbar endoscopy, transforaminal lumbar discectomy, endoscopic approaches for lumbar spinal canal stenosis, and management of chronic low back pain through rhizotomy and rhiziolysis. The endoscopic treatment of basivertebral neuropathy, cervical foraminotomy, and decompression techniques is explained in dedicated chapters. Finally, the book also addresses endoscopic posterior lumbar interbody fusion and procedures for adjacent segment disease after lumbar fusion.
Interventional Pain Surgery is the third of the monograph series. This book comprehensively covers endoscopic techniques for spinal surgery. Topics include interlaminar lumbar endoscopy, transforaminal lumbar discectomy, endoscopic approaches for lumbar spinal canal stenosis, and management of chronic low back pain through rhizotomy and rhiziolysis. The endoscopic treatment of basivertebral neuropathy, cervical foraminotomy, and decompression techniques is explained in dedicated chapters. Finally, the book also addresses endoscopic posterior lumbar interbody fusion and procedures for adjacent segment disease after lumbar fusion.
Key features:
- Covers a wide range of topics in neuroendoscopy and interventional pain medicine
- Emphasizes evidence-based approaches to treatment
- Offers clinical perspectives from expert surgeons
- Includes scientific references for researchers and advanced learners
- It is an essential resource for readers who need to enhance their understanding of the latest technological advancements in neuroendoscopy and interventional pain medicine and apply these innovative techniques to improve patient outcomes.
Readership:
This book is designed for a broad audience, including interventionalists, surgeons, medical students, healthcare professionals, and policy-makers involved in the care of patients with degenerative conditions of the neuroaxis.Table of Contents
PREFACE- LIST OF CONTRIBUTORS
- AND FUTURE TARGETED CARE MODELS TO SUPPORT THE PURSUIT OF HEALTHY
- LONGEVITY
- Álvaro Dowling and Kai-Uwe Lewandrowski
- INTRODUCTION
- Commercialization
- Aging
- Degenerative Musculoskeletal Diseases
- Precision Medicine
- Targeted Care Models
- CONCLUSION
- REFERENCES
- STRATEGIES FOR DEGENERATIVE DISC DISEASE
- Alvaro Dowling, Marcelo Molina, William Omar Contreras López, Morgan P.
- Lorio, Stefan Landgraeber, Jorge Felipe Ramírez León and Kai-Uwe Lewandrowski
- INTRODUCTION
- Normal Structures and Natural Healing
- Normal Structure of the Intervertebral Disc
- Pathophysiology
- Mesenchymal Stem Cells
- Adipose-Derived Stem Cells
- The Difference between White and Brown Adipose Tissue
- Harvesting
- Stem Cell Formation and Identification
- Mesenchymal Stem Cell Injection for DDD
- Mechanism of Action of MSCs for DDD
- MSC Clinical Trials
- Functional versus Structural Improvements
- The Ethics of MSC Therapies
- CONCLUSION
- REFERENCES
- FOR LUMBAR DEGENERATIVE DISC DISEASE AND GLOBAL DISEASE BURDEN DUE
- TO LOW BACK PAIN
- -Álvaro Dowling, Marjan Asefi, Jaime Moyano, Jorge Felipe Ramírez León, KaiUwe
- Lewandrowski and William Omar Contreas López
- INTRODUCTION
- Global Disease Burden
- Degenerative Disc Disease
- The Molecular Basis of Disc Degeneration
- Regenerative Strategies
- Platelet-Rich Plasma (PRP)
- Autologous Bone Marrow Mesenchymal Stem Cells
- Current Evidence for Biologics in Clinical Management of Low Back Pain
- CONCLUSION
- REFERENCES
- DEGENERATIVE INTERVERTEBRAL DISCS
- Alvaro Dowling and Marcelo Molina
- INTRODUCTION
- Annulus Fibrosus Repair
- Tissue Engineering for Annular Repair
- Nucleus Augmentation and Injectables
- Nucleus Replacement and Regeneration
- Biomaterials
- Annulus Fibrosus/nucleus Pulposus Bioengineering Strategies
- DISCUSSION
- CONCLUSION
- REFERENCES
- Alvaro Dowling and Marcelo Molina
- INTRODUCTION
- Physiology
- Endplate and Skeletal Maturity
- Vascularity
- Neuroanatomy of the Vertebral Endplate
- Endplate Failure Modes
- Rationale for Endplate Treatment
- Increasing Endplate Vascularity
- Enhanced Biointegration
- Clinical Studies
- DISCUSSION
- CONCLUSION
- REFERENCES
- INJURY
- Alvaro Dowling and Marcelo Molina
- INTRODUCTION
- Primary Injury
- Secondary Injury
- Chronic Phase and Neurodegeneration
- American Spinal Cord Injury Association Scale
- Determination of Neurological Level of Injury
- ASIA Impairment Scale
- Acute Injury Phase
- History of Cell-based Therapy
- Stem Cell Types
- Bone Marrow-derived Mesenchymal Stem Cells
- Umbilical Cord MSCs
- Adipocyte MSCs
- MSC Transplantation Strategies for Chronic SCI
- MSC Benefit in Chronic SCI
- Biomaterial Scaffolds and Hydrogels
- Clinical Application
- Addressing Ethical Concerns
- DISCUSSION
- CONCLUSION
- REFERENCES
- TUNNEL RELEASE
- Morgan P. Lorio and Paul Paterson
- INTRODUCTION
- Expectations
- Indications
- Contraindications
- Special Considerations
- Special Instructions, Position and Anesthesia
- Tips and Pearls
- SPECTR Tips
- USCTR Tips
- Difficulties
- SPECTR Procedural Steps
- SPECTR Bailout Procedure
- USCTR Procedural Steps
- USCTR Bailout Procedure
- DISCUSSION
- CONCLUSION
- ACKNOWLEDGMENTS
- REFERENCES
- HERNIATED DISC
- Luis Miguel Duchén Rodríguez, Jorge Felipe Ramírez León, Tania Arancibia
- -Baspineiro, Stephan Knoll, Álvaro Dowling, William Omar Contreas López and Kai
- Uwe Lewandrowski
- INTRODUCTION
- Platelet Rich Plasma (PRP)
- Ozone Therapy
- MRI Changes after Intradiscal Ozone Injection
- Clinical Indication for ozone-PRP disc therapy
- Oxygen-Ozone Preparation and PRP Methodology
- Preferred Autologous PRP Protocol
- Injection Technique of Choice
- Clinical Outcomes Following Ozone & PRP Treatment
- DISCUSSION
- CONCLUSION
- REFERENCES
- LUMBAR DEGENERATIVE DISCS
- Álvaro Dowling, Juan Carlos Vera, Jorge Felipe Ramírez León, William Omar
- Contreras López, Morgan P.Lorio and Kai-Uwe Lewandrowski
- INTRODUCTION
- Allogeneic Mesenchymal Stem Cells (MSCs)
- Allogenic Stem Cell Disc Therapy: A Comprehensive Analysis
- Mesenchymal Stem Cell Harvesting and Advanced Expansion Techniques
- Intervertebral Disc Inoculation
- Cohort-analysis
- DISCUSSION
- CONCLUSION
- REFERENCES
- SUBJECT INDEX
