Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.
Table of Contents
1. Immunoassays: an overviewSandeep K. Vashist and John H.T. Luong
2. Antibody immobilization and surface functionalization chemistries for immunodiagnostics
Sandeep K. Vashist and John H.T. Luong
3. Monoclonal antibody generation by phage display: history, state-of-the-art, and future
Christian Hentrich, Francisco Ylera, Christian Frisch and Achim Knappik
4. Bioanalytical requirements and regulatory guidelines for immunoassays
Sandeep Kumar Vashist and John H.T. Luong
5. Enzyme-linked immunoassays
Sandeep K. Vashist and John H.T. Luong
6. Chemiluminescent immunoassays (CLIA)
Sandeep K. Vashist and John H.T. Luong
7. Lateral flow immunoassays
Aart van Amerongen and Marjo Koets
8. Paper-based immunoassays
Zhi Liu, Jie Hu, Zhiguo Qu and Feng Xu
9. Acoustic wave-based immunoassays
Aristea Grammoustianou and Electra Gizeli
10. Interferometry-based immunoassays
P. Petrou, E. Makarona, S. Kakabakos, G. Koukouvinos, K. Misiakos and I. Raptis
11. Nanomaterial- and micromaterial-based immunoassays
Minli You, Zedong Li, Penghui Zhang, Dan Bai, Min Lin and Feng Xu
12. Microcantilever-based sensors
Sandeep K. Vashist and John H.T. Luong
13. Quartz crystal microbalance-based sensors
Sandeep K. Vashist and John H.T. Luong
14. Electrochemical immunosensors fundamentals and applications in clinical diagnostics
Kuldeep Mahato, Suveen Kumar, Ananya Srivastava, Pawan K. Maurya, Renu Singh and Pranjal Chandra
15. Lab-on-a-chip immunoassays
Sandeep K. Vashist and John H.T. Luong
16. Smartphone-based immunoassays
Sandeep K. Vashist and John H.T. Luong
17. Multiplex immunoassays
Sandeep K. Vashist and John H.T. Luong
18. Immunoassays for newborn screening
John H.T. Luong and Sandeep K. Vashist
19. Biotin interference in immunoassays and strategies to tackle it
John H.T. Luong and Sandeep K. Vashist
20. In vitro diagnostic immunoassays for SARS-CoV-2
Sandeep K. Vashist and John H.T. Luong
21. Immunoassays of human immunodeficiency virus (HIV)
John H.T. Luong
22. Immunoassays of hepatitis C virus (HCV)
John H.T. Luong and Sandeep K. Vashist
23. Immunoassays for Ebola virus disease
John H.T. Luong
24. Immunoassays of botulism neurotoxins (BoNTs) of Clostridia
John H.T. Luong
25. Immunoassays of biological warfare agents
John H.T. Luong
26. Lateral flow immunoassays with improved detection sensitivity
John H.T. Luong and Sandeep Kumar Vashist
27. Immunoassays: future prospects and possibilities
Sandeep Kumar Vashist and John H.T. Luong
Authors
Sandeep K. Vashist Senior Global IVD Product Director at Fapon Biotech Inc., Germany.Dr. Sandeep K. Vashist is the Senior Global IVD Product Director at Fapon Biotech Inc., Germany. He held senior R&D and management roles in large IVD giants, such as Bristol-Myers Squibb, Revvity (Immunodiagnostic Systems), and Trivitron Healthcare (Labsystems Diagnostics). Besides, he has been the Chief of the Research Advisory Board at Sensing Self Pte Ltd., Singapore, an Advisory Board Member at Calciscon AG, Switzerland, and a Board Member at Antrum Biotech, South Africa. Sandeep invented and pioneered many CE-certified and/or FDA-approved IVD kits, devices, and technologies. He has 12 patents, over 300 publications, 3 books, and over 9000 international citations. He is the Editor and Reviewer of several journals, funding agencies, and international organizations. Sandeep is an IVD veteran with over two decades of rich global IVD experience.
John H.T. Luong Walton Fellow and Adjunct Professor, Department of Chemistry, University College Cork, Ireland.Prof John H.T. Luong was the Walton Fellow associated with the School of Chemistry of University College Cork, Ireland. He was the Professor and Division Head of Biomedical Engineering at Nanyang Technological University, Singapore. He was also a distinguished Visiting Professor at the University of Zhengzhou (China), a Visiting Professor at Nanocore, National University of Singapore, Bar-Ilan University (Ramat Gan-Israel), Institut d'Electronique, de Micro�lectronique et de Nanotechnologie, Universit� de Lille (France), and Delhi Technological University, India. He has received several awards for his excellent contribution to research, innovation, and technology transfer. He is on the Editorial Board of several Journals, the Chief Editor of MDPI Journal of Functional Biomaterials-Antimicrobials, and the Associate Editor of MDPI Macromolecule. He has 10 patents and 350 publications with over 31,000 citations with an h-index of 89. He is the expert/reviewer/advisor/consultant for many international funding agencies and enterprises.
