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Pharmacology, Physiology, and Practice in Obstetric Anesthesia

  • Book

  • March 2025
  • Elsevier Science and Technology
  • ID: 5994656

Pharmacology, Physiology, and Practice of Obstetric Anesthesia provides all the essentials of obstetric anesthesia in a straightforward, user-friendly format that avoids encyclopedic language and lengthy discussions, and is inclusive of other healthcare specialties and sub-specialties including obstetrics, neonatal care, and more. Coverage spans the essentials of obstetric as well as overlooked issues including obstetric pharmacology and physiology safe practice strategies, clinical concepts for vaginal delivery and c-section, high-risk pregnancy states and management of the complicated parturient, complications and medicolegal, fetus and newborn considerations, and guidelines, standards and statements related to obstetric anesthesia.

Pharmacology, Physiology, and Practice of Obstetric Anesthesia is the perfect reference for an interdisciplinary group of health professionals, policymakers, and researchers working and training in the field of obstetric anesthesiology.

Table of Contents

Part 1: Obstetric Pharmacology, Physiology and Safe Practice Strategies
1. Physiological maternal adaptive changes during pregnancy, e.g., alterations of endometrium and decidua, menstruation, placenta, fetal membranes, placental hormones, morphological and functional fetal development
2. Anatomy of the reproductive tract, including the placenta, uteroplacental circulation, anatomy, transfer of drugs and respiratory gas exchange
3. Obstetric anesthesia and uterine blood flow
4. Perinatal pharmacology
5. Parturient anesthesia assessment and evaluation
6. Point of Care coagulation testing for obstetric hemorrhage
7. How to create a maintain a safe and efficient obstetric anesthesia practice

Part 2: Clinical Concepts of Obstetrics and Anesthesia for Vaginal Delivery and C-Section
8. Obstetric anesthesia consultation
9. Obstetric management of labor and delivery, including preoperative assessment and basic standards for pre-anesthesia care
10. Fetal assessment and physiology
11. Opioid analgesics in labor
12. Mechanisms of labor pain and anesthesia in healthy patients
13. Non-opioid analgesia
14. Non-pharmacologic and alternative management of labor and delivery
15. Local anesthetics and adjuvants in healthy obstetric patients
16. Epidural anatomy and epidural anesthesia for labor and C-section

Part 3: Neuraxial Analgesia for Labor and C-section
17. Neuraxial analgesia and anesthesia for vaginal delivery
18. Neuraxial analgesia for caesarean delivery
19. General anesthesia for normal, uncomplicated C-sections: indications and strategies
20. Airway management of the pregnant patient for labor and C-section
21. Postoperative anesthesia management for postoperative C-section including (TAP block)
22. Postoperative sterilization surgery and anesthesia considerations
23. Anesthesia for assisted reproductive techniques

Part 4: High-Risk Pregnancy States: Evaluation and Management of the Complicated Parturient
24. Anesthesia considerations for pregnant cardiac patients
25. Anesthesia considerations for pregnant patients with lung disease
26. Anesthesia considerations for diabetic mellitus patients and other endocrine disorders
27. Anesthesia considerations for patients with neurologic disorders in pregnancy
28. Anesthesia considerations for fetal growth restriction, and macrosomia in pregnancy
29. Anesthesia considerations for pregnant patients with morbid obesity and neoplasm
30. Anesthesia considerations for patients with substance abuse or psychiatric disorders
31. Anesthesia considerations for patients with renal, hematologic, connective tissue, and immunologic diseases
32. Anesthesia considerations for patients with spine surgery
33. Anesthesia considerations for patients with COVID-19
34. Anesthesia considerations for patients with preeclampsia
35. Anesthesia considerations for patients with infections, HIV, and sexually transmitted diseases
36. Anesthesia considerations with multiple births and fetal malpresentation
37. Anesthesia considerations for vaginal birth after C-section, and for abnormalities of the reproductive tract
38. Anesthesia considerations for non-obstetric surgery during pregnancy
39. Anesthesia considerations for rare obstetric procedures: cerclage placement, external cephalic version, fetal intrauterine procedures

Part 5: Obstetric Complications
40. Peripartum hemorrhage and maternal resuscitation
41. Trauma and critical care during pregnancy
42. Postdural puncture headaches
43. Fetal and neonatal assessment of complications and injuries (including abnormal labor), e.g., dystocia abnormalities of expulsive forces, abnormal presentation, position and development, and pelvic contraction
44. Hypotension and hypertension management
45. Pulmonary aspiration and interventions to reduce aspiration
46. Amniotic fluid embolism
47. Intraamniotic infection
48. Preterm birth
49. Neurologic complications from regional anesthesia and general anesthesia in obstetric practice
50. Anesthesia-related morbidity and mortality (both intraoperative and postoperative) as well as extremes of reproductive life and abortion
51. Anesthesia for fetal surgery
52. Obstetric anesthesia and medicolegal/ethical issues

Part 6: Fetus and Newborn Considerations
53. Fetal evaluation, including the premature fetus and the compromised fetus
54. Fetal and neonatal complications and treatment, including resuscitation
55. Diagnosis and treatment of fetal/newborn asphyxia and respiratory failure
56. Retrolental fibroplasia and anesthesia
57. Long-term effects of anesthetics on the fetal and neonate

Authors

Alan D. Kaye LSU School of Medicine. Aaron J. Kaye Wake Anesthesia, USA.

Dr. Aaron Joshua Kaye, MD attended and graduated from Stanford University in Palo Alto, California and the Medical University of South Carolina in Charleston, South Carolina. He completed his anesthesia residency at the Medical University of South Carolina in Charleston, South Carolina and is in private practice with Wake Anesthesia in Raleigh, North Carolina.