Biomedical Applications of Perovskites: The Era of Bio-Piezoelectric Systems focuses on recent developments in the area of piezoelectric systems and their biomedical applications. A compilation of 19 edited chapters covers different piezoelectric materials, device designs, and their use cases. Readers will be familiarized with the many perovskite materials being used in research and development as well as the role they play in designing novel medical devices and biomaterials.
Key Features
- Systematically explains the piezoelectric perovskite materials starting from their introduction, their structure and synthesis techniques
- Explains the key materials used in devices such as pacemakers and nanogenerators
- Highlights a range of applications including bone regeneration and growth, bone replacement, tissue engineering, dental science, neurotrauma and neurodegenerative disease treatment and bionic prosthesis
- Discusses future challenges and the roadmap for piezoelectric perovskite materials
- Presents scientific references for advanced reading
Readership
Researchers, professionals and students in biomedical engineering programs; Science readers who want to learn about perovskites and associated devices in-depth.
Table of Contents
CONTENTS
PREFACE
LIST OF CONTRIBUTORS
CHAPTER 1 INTRODUCTION TO PIEZOELECTRIC PEROVSKITES
- Neetu Dhanda, Preeti Thakur and Atul Thakur
1. INTRODUCTION
1.1. Piezoelectricity
2. PIEZOELECTRIC MATERIALS
2.1. Perovskite-Type Piezoelectric Substances
2.2. Utilizations of Piezoelectric Materials
3. ELECTRIC FIELD-INDUCED STRAIN IN PEROVSKITE-BASED MATERIALS
3.1. Piezoelectric Effect
3.2. Electrostriction
3.3. Domain Switching
3.4. Volume Adjustment
4. TRENDS IN APPLICATION DEVELOPMENT
4.1. Standard Technologies
4.1.1. Ultrasonic Disposal Technology
4.1.2. Contaminated Gas Reduction
4.1.3. New Energy-Harvesting Technologies
4.1.4. Medical Devices
4.2. Emerging Technologies
4.2.1. Infectious Illnesses
4.2.2. Natural Calamities
CONCLUSION
REFERENCES
CHAPTER 2 TECHNIQUES FOR THE SYNTHESIS OF PIEZOELECTRIC PEROVSKITES 22
- Rohit Jasrotia, Himanshi, Jyoti Prakash and Abhishek Kandwal
1. INTRODUCTION
2. SYNTHESIS TECHNIQUES
2.1. Co-precipitation Method
2.2. Hydrothermal Method
2.3. Solid-State Reaction Method
2.4. Pechini Method
2.5. Sol-Gel Auto-Combustion Method
2.6. Low-Temperature Combustion Sythesis (LCS)
2.7. Pulsed-Laser Decomposition (PLD)
CONCLUSION
REFERENCES
CHAPTER 3 STRUCTURAL ANALYSIS OF PIEZOELECTRIC PEROVSKITE MATERIALS
- Anu Singh, Ritesh Verma, Preeti Thakur, Atul Thakur and Fayu Wan
1. INTRODUCTION
2. PEROVSKITE MATERIALS
3. STRUCTURE OF PEROVSKITE
3.1. Structure
3.2. Distortion in the Perovskite Structure
4. EFFECT OF PARAMETERS ON STRUCTURE
4.1. Effect of Synthesis Condition on Structure
4.2. Effect of Temperature on Structure
4.3. Effect of Doping on Structure
5. PIEZOELECTRIC PEROVSKITE MATERIALS FOR BIOMEDICAL DEVICES
CONCLUSION
REFERENCES
CHAPTER 4 FERROELECTRIC AND PIEZOELECTRIC RESPONSE OF PEROVSKITES 60
- Saarthak Kharbanda, Ritesh Verma, Fayu Wan, Preeti Thakur and Atul Thakur
1. INTRODUCTION
1.1. Overview of Perovskite Materials and their Structural Characteristics
1.2. Importance of Ferroelectric and Piezoelectric Properties in Perovskites
1.3. Relationship between Crystal Structure and Ferroelectric/piezoelectric Properties
2. FERROELECTRICITY IN PEROVSKITES
2.1. Definition and Characteristics of Ferroelectric Materials
2.2. Basic Concepts of Ferroelectric Domains, Polarization, and Spontaneous Polarization
2.3. Mechanisms of Ferroelectricity in Perovskites
3. FERROELECTRIC PHASE TRANSITIONS
3.1. Overview of Ferroelectric Phase Transitions in Perovskites
3.2. Influence of Temperature, Pressure, and Electric Field on Phase Transitions
4. PIEZOELECTRICITY IN PEROVSKITES
4.1. Definition and Principles of Piezoelectricity
4.2. Explanation of the Piezoelectric Effect and its Manifestation in Perovskite Materials
4.3. Relationship between Ferroelectricity and Piezoelectricity in Perovskites
5. APPLICATIONS OF FERROELECTRIC AND PIEZOELECTRIC PEROVSKITES
6. CHALLENGES AND FUTURE PERSPECTIVES
CONCLUSION
REFERENCES
CHAPTER 5 “PEROVSKITE”: A KEY MATERIAL FOR THE BIOMEDICAL INDUSTRY 82
- Ankush Sharma, Ankush Chauhan, Ritesh Verma, Hui-Min David Wang, Preeti Thakur and Atul Thakur
1. INTRODUCTION
1.1. X-Ray Detection and Imaging Using Perovskite Materials
1.2. In Vitro Applications of Magnetic Perovskite Nanoparticles
2. BIOCOMPATIBILITY AND CYTOTOXICITY OF HYDROXYAPATITE-CATIO3 COMPOSITE
CONCLUSION
REFERENCES
CHAPTER 6 PEROVSKITES AS BIOCOMPATIBLE MATERIALS
- Deepa Suhag, Moni Kharb, Hui-Min David Wang, Preeti Thakur and Atul Thakur
1. INTRODUCTION
2. PEROVSKITE STRUCTURE AND PROPERTIES
2.1. Structure
2.2. Magnetic Properties
2.3. Optical Properties
2.4. Superconductivity
3. SYNTHESIS OF PIEZOELECTRIC PEROVSKITES
4. APPLICATIONS
4.1. Glucose Sensor
4.2. Catalyst
4.3. Sensors for Neurotransmitters
4.4. Gas Detectors
4.5. Solar Cells
4.6. Particulate Oxygen Fuel Cells
4.7. Perovskites for X-Ray Detection and Imaging
4.8. Adsorption of Bovine Serum Albumin (BSA)
5. IN VITRO BIOCOMPATIBILITY OF PEROVSKITE COMPOSITES IN CELLULAR CULTURES
CONCLUDING REMARKS
REFERENCES
CHAPTER 7 IMPACT OF PEROVSKITES ON CELL RESPONSE
- Deepa Suhag and Moni Kharb
1. INTRODUCTION
2. ROUTES OF EXPOSURE
3. POLLUTION AND EXPOSURE SOURCES
3.1. Endogenous Exposure Routes
4. THE SIGNIFICANCE OF ENM (ENGINEERED NMS) TOXICITY STUDIES
5. HAZARDOUS PROPERTIES OF SOLAR PANEL MATERIALS
5.1. Pulmonary Toxicity
5.2. Cardiovascular System
5.3. Testosterone Toxicity
5.4. Consequences of Toxicity on Other Organs
6. CHARACTERIZATION OF HYBRID HALIDE PEROVSKITES
7. CELLULAR EFFECT OF PEROVSKITES
7.1. On Respiratory Organs
7.2. On Cranial System
7.3. Cell Membrane Damage
7.4. The Membrane Disruption of Neuronal Cells
7.5. Concerning Lung Epithelial Cell Integrity
8. PEROVSKITES ABSORPTION INTO CELLS
8.1. Cells Internalize
9. VIABILITY EVALUATION
10. CELL DIVISION UNDER PEROVSKITES EXPOSURE
10.1. Mitochondrial Function Changes Following Perovskite Exposure
10.2. The Toxicity Effect of Perovskites by Genome Profiling
11. FUTURE DEVELOPMENT
CONCLUSION
REFERENCES
CHAPTER 8 ANTI-MICROBIAL ACTIVITY OF PEROVSKITES
- Abinaya Elango, Arunkumar Radhakrishnan and Ankush Chauhan
1. INTRODUCTION
2. BIOMEDICAL APPLICATIONS OF PEROVSKITES
3. TYPES OF PEROVSKITES MATERIALS
4. ANTIMICROBIAL ACTIVITIES OF PEROVSKITES
5. APPLICATIONS OF ANTIMICROBIAL PROPERTIES OF PEROVSKITES
5.1. Antimicrobial Coatings
5.2. Water Purification
5.3. Air Purification
6. CHALLENGES IN USING PEROVSKITES AS ANTIMICROBIAL AGENTS
CONCLUDING REMARKS
REFERENCES
CHAPTER 9 BONE REGENERATION AND BONE GROWTH USING PEROVSKITES
- A.J. Pavithra, S.D. Anudevi, G.S. Hikku and K. Kumar Ebenezar
1. INTRODUCTION
2. BONE REGENERATION AND GROWTH
3. STAGES OF BONE HEALING
4. FACTORS AFFECTING BONE REGENERATION
5. MATERIAL PROPERTIES THAT AID IN BONE REGENERATION
6. PEROVSKITE MATERIALS IN BONE REGENERATION
- 6.1. Mechanism of Perovskite-mediated Bone Regeneration
7. APPLICATION OF PEROVSKITE IN BONE REGENERATION
8. TREATMENT OF BONE DEFECTS AND FRACTURES
9. ENHANCEMENT OF IMPLANT OSSEOINTEGRATION
10. STRATEGIES FOR BONE TUMOR REGENERATION
11. BIOCOMPATIBILITY AND SAFETY CONSIDERATIONS
11.1. Cytotoxicity and Immunological Response to Perovskite
11.2. Long-term Effects and Degradation of Perovskite Implants
11.3. Regulatory Considerations for Perovskite-based Bone Regeneration
12. CURRENT CHALLENGES AND FUTURE PERSPECTIVES
CONCLUSION
REFERENCES
CHAPTER 10 PEROVSKITES FOR BONE REPLACEMENT
- Leena Bhardwaj, Supriya Kumari, Vijay Kumar, A.C Sun, Atul Thakur and Preeti Thakur
1. INTRODUCTION
2. LATTICE STRUCTURE
3. PROPERTIES
3.1. Dielectric Properties
3.2. Optical Properties
3.3. Ferroelectricity
3.4. Superconductivity
3.5. Piezoelectricity
4. SYNTHESIS OF PEROVSKITE
4.1. Co-Precipitation Method
4.2. Solid-State Reactions
4.3. Hydrothermal Synthesis
4.4. Pechini Method
4.5. Gas Phase Preparations
4.6. Sol-Gel Method
4.7. Low-Temperature Solution Combustion Method
4.8. Microwave Synthesis
5. APPLICATIONS
CONCLUSION
REFERENCES
CHAPTER 11 BONE TISSUE ENGINEERING USING PEROVSKITES IN REGENERATIVE
MEDICINES
- Supriya Kumari, Joydeep Dutta, Leena Bhardwaj and Vijay Kumar
1. INTRODUCTION
2. LATTICE STRUCTURE
Author
- Atul Thakur
- Preeti Thakur
- Ritesh Verma
- Ankush Chauhan
