mRNA Therapeutics Market Report 2025

This mRNA Therapeutics market report provides a comprehensive analysis of the market’s characteristics, size, and growth, including segmentation, regional and country-level breakdowns, competitive landscape, market shares, trends, and strategies. It also tracks historical and forecasted market growth across various geographies.

The mRNA therapeutics market size has grown steadily in recent years. It will grow from $34.76 billion in 2024 to $36.25 billion in 2025 at a compound annual growth rate (CAGR) of 4.3%. The growth in the historic period can be attributed to increasing financial support for the creation of efficient pharmaceuticals and vaccines, the expansion of federal programs dedicated to advancing RNA-based medicines heightened awareness regarding rare genetic diseases, and a rise in the number of clinical trials.

The mRNA therapeutics market size is expected to see steady growth in the next few years. It will grow to $42.23 billion in 2029 at a compound annual growth rate (CAGR) of 3.9%. The growth in the forecast period can be attributed to the growing number of infectious diseases, the increasing number of patients visiting hospitals and clinics, expanding applications of mRNA therapeutics, growing demand for personalized and precision medicine, favorable regulatory environments, and accelerated approval pathways. Major trends in the forecast period include advancements in mRNA delivery technologies, rapid development and adaptation of mRNA vaccines, the emergence of self-amplifying mRNA (saRNA) platforms, the scalability and flexibility of mRNA manufacturing, and the development of novel mRNA modifications.

The mRNA therapeutics market is poised for growth due to the increasing prevalence of long-lasting and communicable diseases. These diseases, which endure for extended periods and can be transmitted between individuals, include conditions such as tuberculosis, HIV/AIDS, and hepatitis. Factors contributing to their rise include global travel and inadequate healthcare infrastructure, which facilitate disease spread and hinder effective management. mRNA therapeutics are pivotal in combating such diseases by swiftly enabling the body to produce proteins that enhance immune responses, thereby accelerating the development of vaccines and treatments. For example, in 2022, the number of people in England living with diagnosed HIV and receiving care rose to 94,397, a 3% increase from 2021, highlighting the need for effective therapeutic advancements.

Leading companies in the mRNA therapeutics market are concentrating on pioneering solutions, such as mRNA-based booster vaccines, to bolster immunity against evolving viral variants. These vaccines utilize messenger RNA (mRNA) technology to extend and enhance immunity against specific pathogens, particularly following initial vaccination series. For instance, Gennova Biopharmaceuticals Ltd. launched India's first indigenous mRNA-based Omicron-specific booster vaccine, GEMCOVAC-OM, in June 2023. Designed to combat the Omicron variant of SARS-CoV-2, GEMCOVAC-OM is thermostable and can be administered without needle injection, facilitating easy deployment in India's last-mile regions. Clinical studies have shown significantly heightened immune responses compared to other vaccines, underscoring the efficacy of variant-specific approaches.

In May 2022, OPKO Health Inc., a US-based pharmaceutical company, acquired ModeX Therapeutics Inc. for around $300 million. The acquisition is designed to strengthen OPKO Health's oncology and infectious disease portfolio by incorporating ModeX's groundbreaking immune therapies. This move aims to expand OPKO’s product pipeline and capitalize on synergies to accelerate development in crucial therapeutic areas. ModeX Therapeutics Inc. is a US-based biotechnology company specializing in mRNA therapeutics.

Major companies operating in the mRNA therapeutics market are Pfizer Inc., Novartis AG, Sanofi AG, AstraZeneca plc, GlaxoSmithKline plc, Hoffmann-La Roche AG, Moderna Therapeutics Inc, BioNTech SE, Vertex Pharmaceuticals Incorporated, Catalent Inc, Alnylam Pharmaceuticals Inc, Sarepta Therapeutics Inc, Arcturus Therapeutics Holdings Inc, CureVac N.V, Ethris GMBH, eTheRNA immunotherapies NV, In-Cell-Art S.A.S., Nutcracker Therapeutics Inc, SCM LifeScience Co Ltd, Suzhou Abogen Biosciences Co Ltd, Tiba Biotech LLC, CSPC Pharmaceutical Group, CRISPR Therapeutics AG.

North America was the largest region in the mRNA therapeutics market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the mRNA therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the mRNA therapeutics market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Messenger RNA (mRNA) therapeutics involve utilizing mRNA molecules to prompt cells to produce therapeutic proteins within the body, aimed at preventing, treating, or curing diseases by facilitating the production of specific proteins necessary for therapeutic benefits.

The primary products in mRNA therapeutics include vaccines and drugs. mRNA vaccines instruct cells via mRNA to generate proteins that stimulate an immune response against targeted diseases. These vaccines find applications across various fields such as infectious diseases, oncology, rare genetic diseases, respiratory illnesses, among others. End users include hospitals, clinics, research organizations, and other healthcare providers.

The mRNA therapeutics market research report is one of a series of new reports that provides mRNA therapeutics market statistics, including mRNA therapeutics industry global market size, regional shares, competitors with a mRNA therapeutics market share, detailed mRNA therapeutics market segments, market trends and opportunities, and any further data you may need to thrive in the mRNA therapeutics industry. This mRNA therapeutics market research report delivers a complete perspective on everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The mRNA therapeutics market consists of revenues earned by entities by providing services such as vaccine development, protein replacement therapies, gene editing, monoclonal antibody production, and cancer treatment. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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