Chronic Rhinosinusitis With Nasal Polyps Market Report 2025

This Chronic Rhinosinusitis With Nasal Polyps market report provides a comprehensive analysis of the market’s characteristics, size, and growth, including segmentation, regional and country-level breakdowns, competitive landscape, market shares, trends, and strategies. It also tracks historical and forecasted market growth across various geographies.

The chronic rhinosinusitis with nasal polyps market size has grown strongly in recent years. It will grow from $4.02 billion in 2024 to $4.4 billion in 2025 at a compound annual growth rate (CAGR) of 9.3%. The growth in the historic period can be attributed to increasing prevalence, growing advancements in diagnosis, increasing treatment innovation, growing patient awareness, and increasing healthcare spending.

The chronic rhinosinusitis with nasal polyps market size is expected to see strong growth in the next few years. It will grow to $6.21 billion in 2029 at a compound annual growth rate (CAGR) of 9%. The growth in the forecast period can be attributed to growing biologic therapies, increasing personalized medicine, advancing technological advancements, increasing regulatory approvals, growing patient-centric care, and monitoring epidemiological trends. Major trends in the forecast period include innovative drug delivery systems, understanding pathophysiology, clinical trials, longitudinal studies, increased awareness, integrated care models, prevalence, and incidence.

The rising prevalence of respiratory diseases is expected to drive growth in the chronic rhinosinusitis with nasal polyps market. These diseases affect the respiratory system, including the lungs and airways, and are influenced by factors such as air pollution, smoking, climate change, infections, occupational exposures, and allergies. Conditions such as asthma and chronic obstructive pulmonary disease (COPD) are increasingly common, leading to higher rates of associated conditions such as CRSwNP. This trend is fueling demand for diagnostic tools, treatments, and surgical interventions. For example, recent data from the National Center for Health Statistics (NCHS) shows an increase in asthma prevalence among U.S. adults from 8.4% in 2021 to 8.7% in 2022, with asthma episodes rising from 3.3% to 3.7% over the same period. As respiratory tract infections become more prevalent, they are expected to further stimulate growth in the chronic rhinosinusitis with nasal polyps market.

Leading companies in the chronic rhinosinusitis with nasal polyps market are prioritizing alternative therapies, such as anti-IL-5 biologics, to improve patient outcomes and strengthen their competitive edge. Anti-IL-5 biologics provide targeted treatment by reducing eosinophilic inflammation in conditions like severe asthma and eosinophilic disorders, enhancing symptom control and quality of life for patients. For instance, in March 2024, Optinose, a U.S.-based pharmaceutical company focused on developing and commercializing innovative products, received U.S. Food and Drug Administration (FDA) approval for XHANCE, a prescription nasal spray indicated for chronic rhinosinusitis (CRS) in adults, including both chronic rhinosinusitis with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP). It contains fluticasone propionate, a corticosteroid that reduces nasal passage inflammation. A key feature is its unique Exhalation Delivery System (EDS), enabling patients to exhale into the device while administering the spray, which enhances medication delivery deep into the nasal passages, effectively targeting areas where nasal polyps form and sinuses drain.

In May 2022, Medtronic Plc, a US-based medical technology solutions company, completed the acquisition of Intersect ENT Inc. for an undisclosed amount. The acquisition adds Intersect ENT's PROPEL and SINUVA sinus implant product lines and technology to Medtronic's existing ear, nose, and throat (ENT) portfolio. Intersect ENT Inc. is a US-based medical technology company specializing in treating chronic rhinosinusitis with nasal polyps.

Major companies operating in the chronic rhinosinusitis with nasal polyps market are Pfizer Inc., Roche Holding AG, Merck & Co Inc, Bayer AG, Sanofi SA, Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis AG, GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Medtronic plc, Boehringer Ingelheim International GmbH, Amgen Inc, Teva Pharmaceutical Industries Ltd, Regeneron Pharmaceuticals Inc, Daiichi Sankyo Company Limited, Olympus Corporation, Eisai Co Ltd, Smith & Nephew PLC, Genentech USA Inc, Mallinckrodt Pharmaceuticals, Lyra Therapeutics Inc, Sunovion Pharmaceuticals, Acclarent Inc., Optinose US Inc, SinuSys Corporation, Biohaven Pharmaceuticals.

North America was the largest region in the chronic rhinosinusitis with nasal polyps market in 2024. The regions covered in the chronic rhinosinusitis with nasal polyps market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the chronic rhinosinusitis with nasal polyps market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is an enduring inflammatory condition affecting the sinuses and nasal passages, characterized by the development of nasal polyps. These polyps are benign, swollen tissues that form in response to ongoing inflammation in the nasal passages or sinuses. Diagnosis typically involves evaluating symptoms, conducting clinical examinations, utilizing imaging techniques, allergy tests, and occasionally performing biopsies.

The primary treatments for chronic rhinosinusitis with nasal polyps encompass both pharmaceutical and surgical approaches. Medications aim to alleviate inflammation, manage symptoms, and reduce the size of polyps. They can be administered via nasal sprays, orally, or through other routes, and are available through hospital pharmacies, retail outlets, and online platforms.

The chronic rhinosinusitis with nasal polyps market research report is one of a series of new reports that provides chronic rhinosinusitis with nasal polyps market statistics, including chronic rhinosinusitis with nasal polyps industry global market size, regional shares, competitors with an chronic rhinosinusitis with nasal polyps market share, detailed chronic rhinosinusitis with nasal polyps market segments, market trends and opportunities, and any further data you may need to thrive in the chronic rhinosinusitis with nasal polyps industry. This chronic rhinosinusitis with nasal polyps market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The chronic rhinosinusitis with nasal polyps market consists of revenues earned by entities by providing services such as medical consultations, diagnostic procedures, pharmacological treatments, and surgical interventions. The market value includes the value of related goods sold by the service provider or included within the service offering. The chronic rhinosinusitis with nasal polyps market also includes sales of nasal corticosteroid sprays, antihistamines, saline nasal sprays, and devices for nasal irrigation, as well as surgical instruments and equipment used in procedures such as polypectomy and functional endoscopic sinus surgery. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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