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Lipid-Drug Conjugates. Innovation and Applications

  • Book

  • March 2025
  • Elsevier Science and Technology
  • ID: 6006248
Lipid-Drug Conjugates: Innovation and Applications highlights the most recent advances and clinical applications of nano lipid-drug conjugates for enhanced drug delivery and targeting in the treatment of cancer, glioblastoma, Alzheimer’s, AIDS, and bacterial diseases. In addition, various conjugation methods to prepare lipid-drug conjugates and their pharmacokinetics in vivo are explored, together with the production and characterization of various delivery carriers for lipid-drug conjugates. The contents of this book provide pharmaceutical science researchers with the tools to explore targeted drug delivery leveraging the unique characteristics of lipid conjugates. Scientists in the corporate setting can benefit of the cases and techniques presented in developing new formulations and products.

Table of Contents

PART A: Innovations in Lipid-Drug Conjugates
1. Lipid-drug conjugates: application of lipid in drug delivery
2. Lipid-drug conjugates: Conjugation methods and therapeutic benefits
3. Route of administration and cellular interaction of lipid-drug conjugates
4. Lipid -drug conjugates for enhanced drug delivery and targeting
5. Antibody conjugated lipid nanoparticles as a targeted drug delivery systems for hydrophobic drugs
6. Pharmacokinetics of lipid-drug conjugates
7. Production and characterization of various delivery carriers for lipid-drug conjugates

PART B: Applications of lipid-drug conjugates
8. Lipid-drug conjugates for cancer chemotherapy
9. Lipid-drug conjugates for enhanced antiretroviral efficacy
10. Nano lipid-drug conjugates for the treatment of Alzheimer disease
11. Lipid-drug conjugates for the treatment of glioblastomas
12. Antibody-drug conjugates as cancer therapeutics
13. Antibacterial drug conjugates for bacterial diseases
14. Lipid-drug conjugates: Future perspectives, Industry trends and global forecast

Authors

Malay K. Das Professor of Pharmaceutics, Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, India.

Malay K. Das (MPharm, PhD) is a Professor of Pharmaceutics at the Department of Pharmaceutical Sciences, Dibrugarh University, in India. His research interests include novel drug delivery systems, pharmaceutical nanotechnology, nanomedicine, and transdermal and targeted drug delivery systems. He has handled several major research projects sponsored by the DST, DBT, ICMR, UGC, and AICTE. Professor Das has been honored with the prestigious DBT-Biotechnology Overseas Associateship at the University of South Florida, Tampa, United States and the DST-UKIERI Research Award in collaboration with the Institute of Pharmaceutical Sciences, King's College, London, United Kingdom. He has several publications including peer-reviewed research and review articles in various international journals, as well as chapters in various books published by international publishers.