Chalcone is one of the most versatile scaffolds with wide range of applications. It is used as a precursor for diverse classes of organic molecules, natural flavonoids and possesses interesting biological activities and physical properties like semiconductor, non-linear optical, fluorescence, and electronic properties to name a few. Chalcones have been the subject of intense research due to their biological activities and the ability to tweak their biological activity and other properties by small changes along the a, b-unsaturated backbone. Besides their inherent biological activities, they have found uses in food industry and cosmetic industry as additives, due to their UV protection properties. They have also found applications as chemosensors and probes. These diverse features make chalcones one of the most fascinating molecules Chalcones and their Derivatives: From Synthesis to Applications features this molecule, different methods and approaches to synthesis, significance of this scaffold in biology, and other diverse fields. It serves as a comprehensive literature guide for researchers and a reference material for the postgraduate students involved with the development and use of chalcone based molecules.
Table of Contents
1. Chalcone as a versatile scaffold: An overview2. Chalcones in Drug Discovery and Medicinal Chemistry
3. Chalcone Derivatives: Synthesis Strategies and Structural Modifications
4. Naturally occurring chalcone derivatives and their biological applications
5. Chalcone based metal complexes and their applications
6. Chalcones and their derivatives as Antioxidants: Mechanisms and Applications
7. Photophysical Behavior of Chalcone Derivatives: Insights and Applications
8. Chalcones as fluorescence chemo-sensors for detection of metal ions
9. Chalcones as functional materials for organic electronics applications
10. Chalcones in the cosmetic industry
11. Chalcones and their derivatives in the food industry
12. Chalcones as Molecular Probes in Chemical Biology and Bioimaging
13. Chalcones in Material Science: From Polymers to Nanomaterials
14. Chalcones in Agricultural Applications: Pesticides and Plant Growth Regulators
15. Chalcone-Based Nanomaterials: Synthesis, Characterization, and Applications
16. Future Perspectives and Emerging Trends in Chalcone Research
Authors
Hao Shao Associate Professor of Medicinal Chemistry in the College of Pharmaceutical Sciences, Southwest University, Chongqing, China. Hao Shao is an Associate Professor in the school of Civil Engineering & Architecture at Anhui University of Technology. He obtained his Ph.D. from China University of Petroleum (East China) and has visited the section of Safety and Security Science at Delft University of Technology (TUD). He is mainly engaged in industrial system resilience assessment and optimization, complex process system reliability, fire and explosion accident intelligent prevention and control research, so as to prevent petrochemical production accidents and provide effective decision-making for petrochemical production process. His relevant researches provide new ideas and contributions to the development of risk assessment and resilience assessment and optimization methodologies. Mohmmad Younus Wani Assistant Professor, Department of Chemistry, College of Science, University of Jeddah, Kingdom of Saudi Arabia. Mohmmad Younus Wani, PhD, Assistant Professor, Department of Chemistry, College of Science, University of Jeddah, Kingdom of Saudi Arabia. Dr. Wani graduated from Jamia Millia Islamia, New Delhi, India in 2013. Received a senior research fellowship from CSIR-India in 2012 and FCT postdoctoral fellowship from Portugal in 2013. Worked as a postdoctoral fellow with Prof. A. Sobral group from 2013-2016 on the development of fungal cell wall targeted antifungal therapies. In fall 2016, Dr. Wani moved to the University of Texas, USA, Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, UTHealth on the development of non-traditional antimicrobial agents and strategies combating multi-drug resistance. He has many international publications, book chapters, and a book, besides many international and national honours and awards to his credit. Dr. Wani is working hard to advance the medicinal chemistry and drug discovery field with new questions and pertinent issues of 21st century. Anish Khan Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.Dr. Anish Khan is currently working as Assistant Professor in Chemistry Department, Centre of Excellence for Advanced Materials Research (CEAMR), Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia. Completed Ph.D. from Aligarh Muslim University, India in 2010. Completed Postdoctoral from School of Chemical Sciences, University Sains Malaysia (USM) in Electroanalytical chemistry in 2010. Working in the field of synthetic biosensor, polymer composites, organic-inorganic electrically conducting nanocomposites. More than 200 research articles, 70 book chapters 30 books published in referred international publisher and more than 20 international conferences/ workshop. More than 30 research projects completed. Editorial board member of more than 11 international journals. Member of American Nano Society.
Shafat Ahmad Khan Associate Professor, School of Basic and Applied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India. Shafat Ahmad Khan (PhD 2012, Jamia Millia Islamia, New Delhi, INDIA) has significant teaching and research experience in Organic Chemistry, Green Materials, and plant products (20+ publications, book chapters, h-index 10, 963 citations, 2 patents (filed), 1 edited book). Currently, he is working as Associate Professor in Galgotias University, Greater Noida, U.P., INDIA.
