Organoids and Spheroids Market Report 2025

This Organoids and Spheroids market report provides a comprehensive analysis of the market’s characteristics, size, and growth, including segmentation, regional and country-level breakdowns, competitive landscape, market shares, trends, and strategies. It also tracks historical and forecasted market growth across various geographies.

The organoids and spheroids market size has grown exponentially in recent years. It will grow from $1.16 billion in 2024 to $1.45 billion in 2025 at a compound annual growth rate (CAGR) of 24.6%. The growth in the historic period can be attributed to rapid progress in stem cell research and 3d cell culture technologies, increased funding and investments, rise in chronic diseases, increased use of organoids and spheroids in drug screening and toxicology studies, progress in regenerative medicine and personalized medicine approaches, favorable regulatory frameworks supporting the use of advanced cell culture models in research.

The organoids and spheroids market size is expected to see exponential growth in the next few years. It will grow to $3.46 billion in 2029 at a compound annual growth rate (CAGR) of 24.4%. The growth in the forecast period can be attributed to continued technological advancements, expansion of personalized medicine, enhanced applications in cancer research, ethical and regulatory evolution, growth in commercial products and services based on organoid and spheroid technologies, increased educational initiatives to train researchers in organoid and spheroid technologies. Major trends in the forecast period include integration with advanced technologies, expansion of high-throughput screening methods using organoids for drug discovery, 3D bioprinting and bio fabrication, increasing use of organoids for modeling various cancers, and integration of organoids with microfluidic systems.

The growing demand for cell therapy and tissue engineering is expected to drive the expansion of the organoids and spheroids market in the future. Cell therapy and tissue engineering involve utilizing living cells or engineered tissues to replace, repair, or regenerate damaged tissues and organs in the body. This demand is increasing due to the potential of these therapies to regenerate damaged tissues and treat conditions previously considered incurable, thus providing innovative solutions in regenerative medicine. Organoids and spheroids are used in cell therapy and tissue engineering to model complex tissues and test therapeutic approaches in vitro. For example, in February 2023, Cell & Gene, a U.S.-based online resource for research scholars, reported that there were 27 FDA-approved cell and gene therapies (CGTs), representing about 8% of the 340 biologics approved in 2022, an increase from 22 approvals in 2021. This growing demand for cell therapy and tissue engineering is anticipated to support the growth of the organoids and spheroids market.

Leading companies in the organoids and spheroids market are concentrating on developing advanced tools, such as single-particle dispensers, to enhance precision in cell handling and improve the reproducibility of research outcomes. Single-particle dispensers are high-precision instruments designed to isolate and dispense individual cells or particles, enabling accurate control in research and diagnostic applications. For example, in July 2024, SEED Biosciences, a biotechnology company based in Switzerland, launched Dispen3D, an innovative tool for accurately dispensing individual spheroids and organoids, representing a significant advancement in 3D cellular model handling. This dispenser allows researchers to transfer single spheroids into multi-well plates swiftly and precisely, automating the process and ensuring monoclonality, which is essential for drug discovery and personalized medicine. Dispen3D operates at low pressures, delicately treating fragile cells to maintain their structural integrity and viability, while its user-friendly design allows for seamless integration into diverse research settings, meeting the increasing demand for advanced instruments in biological sciences.

In February 2024, Cell Microsystems, a U.S.-based biotechnology company, formed a strategic partnership with OMNI Life Science to significantly advance life science research in North America through the introduction of advanced cell analysis tools. This collaboration focuses on launching three innovative products: the TIGR Tissue Grinder & Dissociator, the CASY Cell Counter and Analyzer, and the CERO 3D Cell Culture Incubator & Bioreactor. OMNI Life Science, a Germany-based company, specializes in laboratory instrumentation and solutions for life sciences research.

Major companies operating in the organoids and spheroids market are Thermo Fisher Scientific Inc., Merck KGaA, Corning Incorporated, Lonza Group AG, StemCell Technologies Canada Inc., Greiner Bio-One International AG, Promega Corporation, Molecular Devices LLC, American Type Culture Collection (ATCC), Mimetas B.V., InSphero AG, HUB Organoids, Emulate Inc., 3D Biomatrix Inc., Prellis Biologics Inc., 3D Biotek LLC, DefiniGEN Limited, Visikol Inc., Organovo Holdings Inc., Cellesce Ltd., AMS Biotechnology (Europe) Limited.

North America was the largest region in the organoids and spheroids market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the organoids and spheroids market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the organoids and spheroids market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Organoids and spheroids are advanced 3D cell culture systems designed to replicate the structure and function of organs and tissues. Organoids are small, simplified versions of organs created from stem cells, while spheroids are spherical clusters of cells that can model tumor environments or various tissue types. These systems are utilized for research purposes such as disease modeling and drug testing.

The primary types of these models are organoids and spheroids. Organoids are miniature organ replicas grown in vitro from stem cells, used for investigating organ development, disease mechanisms, and drug effects. Techniques for generating organoids include the extracellular matrix scaffold method, spinning bioreactor method, hanging drop method, low adherent culture plate method, magnetic levitation method, and others. Applications of these models span developmental biology, personalized and regenerative medicine, disease pathology, drug toxicity studies, and efficacy testing. Key users include the biotechnology and pharmaceutical industries, academic and research institutions, and hospitals and diagnostic centers.

The organoids and spheroids market research report is one of a series of new reports that provides organoids and spheroids market statistics, including the organoids and spheroids industry's global market size, regional shares, competitors with an organoids and spheroids market share, detailed organoids and spheroids market segments, market trends and opportunities, and any further data you may need to thrive in the organoids and spheroids industry. This organoids and spheroids market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The organoids and spheroids market includes revenues earned by entities by providing services such as drug discovery and testing, toxicology screening, personalized medicine, regenerative medicine research, cancer research, stem cell research, and gene editing studies. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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