+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

Kumar & Clark's Cases in Clinical Medicine. Edition No. 5

  • Book

  • April 2025
  • Elsevier Health Science
  • ID: 6016276
This award-winning book provides a comprehensive collection of over 200 real-life clinical cases designed to support clinical reasoning and enhance diagnostic and management skills through case-based learning.

The cases cover a wide range of acute symptoms and conditions encountered in medicine, with clear and concise advice on diagnosis and management. The level of detail is ideal for exam revision as well as to support junior doctors and other healthcare professionals on the wards.

Now in its fifth edition, this latest Kumar & Clark has been fully updated by new editors who bring a wealth of clinical experience as well as a recent junior doctor perspective to this highly useful book.
  • More than 200 clinical cases covering various acute symptoms and conditions
  • Includes the most common MLA conditions
  • Concise, relevant, and fully updated with evidence-based information and the latest guidelines
  • Clear advice on immediate and further management, complications, differential diagnoses, history-taking, tips, pitfalls, alerts, investigations, and prioritisation
  • Key points reinforced through ‘Remember’, ‘Investigations’ and ‘Information’ boxes
  • High-quality diagrams, tables, and photographs throughout
  • An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud
  • New sections on palliative care, ophthalmology, and metabolic bone diseases
  • Expanded dermatology chapter
  • Fully updated and aligned to latest guidelines

Table of Contents

1 Infectious Diseases

Pyrexia of unknown origin (PUO)

Septicaemia

Meningococcal meningitis and septicaemia

Brain abscess

Pseudomembranous colitis

Food poisoning

Typhoid

The returning traveller

Shingles

Epstein-Barr virus

2 Sexually Transmitted Infections

HIV/AIDS

Vaginal discharge

Urethral discharge and genital ulcers/warts

3 Nutrition

Feeding the patient

4 Gastroenterology

Vomiting

Hiccups

Weight loss

Dysphagia

Constipation

Diarrhoea

Abdominal pain

Gastro-oesophageal reflux disease (GORD)

Barrett’s oesophagus

Peptic ulcer disease

Rectal bleeding

Family history of colon cancer

Functional bowel disease

5 Liver and Biliary Tract Disorders

Abnormal liver biochemistry

Jaundice

Acute liver disease

Ascites

Haematemesis and melaena

Non-alcoholic fatty liver disease

Liver failure

Excess alcohol use

Cholecystitis

Acute cholangitis

6 Haematology and Oncology

Microcytic and macrocytic anaemia

Iron deficiency anaemia

Haemolytic anaemia

Elevated haemoglobin (polycythaemia)

Elevated white blood cell count

Elevated platelet count

Platelet disorders

Bleeding disorders

Disseminated intravascular coagulation (DIC)

Thrombosis

Thrombosis and the anti-phospholipid syndrome

Sickle-cell disease

Types of sickle-cell disease

Glucose-6-phosphate dehydrogenase deficiency

Splenomegaly, splenectomy and hyposplenism

Blood transfusion

Haematological oncology

Anaemia in rheumatoid arthritis

Anaemia in cancer

Infection/sepsis

7 Care of the Elderly and Palliative care

Blackouts

Falls in the elderly

Benign paroxysmal positional vertigo

Delirium

Dementia

Depression

Non-specific presentation of illness in the elderly

Appropriate assessment scales

Stroke

Heart disease in the elderly

Transient ischaemic attack

Hypothermia

Pressure ulcers

Urinary tract infection and incontinence

Arteritis

Acute hot joint [consider removal - does not add much not already covered]

Parkinson’s disease

Drug treatment in older people/drug treatment as a cause of illness and admission to hospital

Drugs as a cause of illness and delayed discharge

Do not attempt resuscitation (DNAR) decision-making

Palliative care symptom management

8 Rheumatology

Osteoarthritis (OA)

Rheumatoid arthritis (RA)

SLE and vasculitis

Acute autoimmune rheumatic disease

Reactive arthritis

Crystal arthritis

Polymyalgia rheumatica/giant cell arteritis

Polymyositis and dermatomyositis

Acute back pain

Severe back pain/osteoporosis

Osteomyelitis

Septic arthritis

9 Kidney and Urinary Tract Disease

Presentation of kidney and urinary tract disease

Fluid balance and electrolytes: assessing fluid status

Fluid balance and electrolytes: sodium problems

Patient stopped passing urine

Acute heart failure

Hyperkalaemia

The acidotic patient

Acute kidney injury

Chronic kidney disease

Multisystem vasculitis/acute glomerulonephritis

Intercurrent illness in dialysis and transplant patients

Nephrotic syndrome

Haematuria without albuminuria

Urinary tract infection (UTI)

Renal and ureteric colic

10 Cardiology

Syncope

A clinical approach to patients with tachycardia

Atrial fibrillation

Bradycardia and pacing

Cardiac arrest and basic life support

Chest pain and acute coronary syndromes

Thrombolysis

Acute myocardial ischaemia

Cardiogenic shock

Right ventricular infarction

Heart failure following an MI

Post-infarction arrhythmias and heart block

Myocardial infarction - secondary prevention

Heart failure recognition and acute management

Pericardial disease [include tamponade, pericarditis]

Valvular heart disease

Infective endocarditis

Pulmonary hypertension

Cardiomyopathies

Hypertension (HT)

The swollen/painful leg

11 Respiratory Disorders

Acute breathlessness

Cough

Breathlessness and wheeze

Hyperventilation

Haemoptysis

Chest pain

Bronchiolitis [add other childhood differentials]

Respiratory failure

COPD - acute exacerbation

Pneumonia

COVID

Lung abscess

Tuberculosis

Pleural effusion

Pulmonary embolism

Pneumothorax

Carcinoma of the bronchus

Sarcoidosis

12 ITU

Shock

Anaphylaxis

Acute lung injury/Acute Respiratory Distress Syndrome (ARDS)

13 Poisoning

Self-poisoning

Paracetamol (acetaminophen) poisoning

Salicylate overdose

Cocaine

Gammahydroxybutyric acid (GHB)

Insect stings and bites

14 Endocrinology and Diabetes

Diabetes mellitus

Diabetic ketoacidosis (DKA)

Hyperosmolar hyperglycaemic state

Hypoglycaemic coma

Sick diabetic patient

Management of new type 2 diabetic presenting for surgery

Urgent surgery in patients with diabetes

Diabetic foot

Diabetes in pregnancy

Cushing’s syndrome

Hyperthyroidism

Amiodarone and thyroid function

Hypothyroidism

Addison’s disease

Patients on steroids for surgery

Metabolic bone diseases (add osteomalacia, Paget’s disease of bone - inc. summary data interpretation of)

Hypercalcaemia

Severe hypercalcaemia

Hypocalcaemia

Phaeochromocytoma (catecholamine crisis)

Hypopituitarism

Diabetes insipidus

Syndrome of inappropriate anti-diuretic hormone (SIADH)

15 Neurology

Diplopia

Loss of vision

Ophthalmology

Bell’s palsy

Vertigo

Stroke

Subdural haemorrhage

Encephalitis

Meningitis [moved position]

Traumatic brain injury

Severe brain injury

Fits and faints

Headaches

Falls [moved position]

Difficulty walking [moved position]

Movement disorders [moved position]

Parkinson’s disease [moved position]

Multiple sclerosis (MS) [moved position]

Guillain-Barr� syndrome

Spinal cord compression

16 Psychiatry

Delirium

Drugs and poisons as causes of delirium

Dementia

Delirium tremens (DT)

Depression

Suicide and deliberate self-harm (DSH)

Acute anxiety

Opiate dependence

ADHD

The disturbed patient

17 Dermatology

A swollen red leg

Generalised rash or eruption [moved position]

Pruritus [moved position]

Eczema

Psoraisis

Urticaria and angio-oedema

Skin nodules [Case]

- Case of Malignant melanoma

- Differentials BCC, SCC, warts, dermatofibroma, pyogenic granuloma

Cutaneous adverse drug reactions (ADR)

Sun-induced rash [moved position]

Erythema nodosum [moved position]

HIV and the skin

Authors

Philip Xiu GP Registrar, Yorkshire Deanery, Leeds, UK. Philip Xiu a GP Registrar, Yorkshire Deanery, Leeds, UK. Nicholas Aveyard Anaesthetic Registrar, Royal Devon University Healthcare NHS Foundation Trust NIHR Academic Clinical Fellow, University of Exeter, UK. Nicholas Aveyard is Anaesthetic Registrar, Royal Devon University Healthcare NHS Foundation Trust NIHR Academic Clinical Fellow, University of Exeter.