After an overview of the barriers to genomics and proteomics delivery, the book dives into physical, chemical, and biological methods of gene delivery. Further chapters extensively discuss the delivery of proteins and therapeutic peptides through the respiratory, oral, parenteral, transdermal, topical, uterine, and rectal pathways. This book is the ideal reference for pharmaceutical scientists dealing with gene and protein/peptide delivery. Regulators and corporate researchers can also benefit from the wide coverage of delivery methods presented.
Table of Contents
1. Barriers to Gene and Protein Delivery2. Gene Delivery Using Physical Methods
3. Gene Delivery Using Chemical Methods
4. Gene Delivery Using Viral Vectors
5. RNA based therapeutics
6. Protein and Peptide Delivery through Respiratory Pathway
7. Oral Delivery of Proteins and Peptides: Concepts and Applications
8. Parenteral Delivery of Peptides and Proteins
9. Other Routes of Protein and Peptide Delivery: Transdermal, Topical, Uterine, and Rectal
10. Computational tools in genomics and proteomics
11. CRISPR/Cas9 gene-editing for treating gene and protein disorders
12. Regulatory guidance on therapeutic proteomics and genomics
Authors
Aliasgar Shahiwala Dubai Pharmacy College for Girls, United Arab Emirates. Dr. Aliasgar Shahiwala is currently serving as a Professor in the Department of Pharmaceutics, and Graduate Program Director, at Dubai Pharmacy College, Dubai, UAE. He received his MA and PhD in pharmaceutics and pharmaceutical technology from the Maharaja Sayajirao University of Baroda, India, with a particular research focus on the area of novel drug delivery. His postdoctoral research at Northeastern University, USA, centered on applications of nanotechnology in the field of drug delivery and drug targeting. With more than 20 years of teaching and research experience, Prof. Shahiwala has published several articles in international peer-reviewed journals, edited 4 books, and authored many book chapters, as well as being an active reviewer and editorial board member. Naazneen Surti CVM University, Gujarat, India.Dr. Naazneen Surti is currently working as a Professor with Indukaka Ipcowala College of Pharmacy, CVM University. She holds the degree of Bachelor of Pharmacy, Master of Pharmacy in Pharmaceutics, and a Ph.D. in Pharmacy (Pharmaceutics) from The Maharaja Sayajirao University of Baroda, India. She is a seasoned professional with 24 years of experience which is a blend of industrial experience and academia. Her area of specialization is development of novel drug delivery systems. She has guided more than 45 students for their PG dissertations, 3 students for PhD and 6 industry defined projects. Dr. Naazneen surti holds two Indian patents, has several book chapters and has over 40 research publications in national and international journals of repute. She is a recipient of research project grant and seminar grant from GUJCOST and Women Scientist scholarship from DST under WOS-A scheme.
