Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituitary-adrenal (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.
Table of Contents
1. Introduction to physiology and neurobiology of stress2. Mechanisms underlying stress effects on the brain
3. Early Life Stress and Brain Development: Neurobiological and behavioral effects of chronic stress
4. Molecular mechanisms underlying stress response and adaptation
5. The Effects of Stress on Cognitive Performance
6. Stress and sleep: What's the link?
7. Stress-Related psychiatric disorders
8. Stress and the Gut Microbiota-Brain Axis
9. Epigenetic Regulation of Stress
10. Mapping Neural Networks in Stress-Brain Connectivity
11. Stress-related Neurodegenerative Diseases: Molecular Mechanisms Implicated in Neurodegeneration and Therapeutic Strategies
12. The Stress-Immune System Axis: Exploring the Interplay Between Stress and Immunity
13. Stress and Gender Differences in Brain Development
14. Models developed to explain the effects of stress on brain and behaviour
15. Novel treatment and strategies targeting stress-related disorders
16. Stress in Specific Population: Cognitive Decline in Aging, Occupational Challenges, Strategies for Medical Professionals”
17. Addiction and Stress: Exploring the reward pathways in brain affected by different drugs
18. Stress-Induced Neurodegeneration and Behavioral Alterations in Caenorhabditis elegans: Insights into the Evolutionary Conservation of Stress-Related Pathways and Implications for Human Health
19. The Neuroscientific Basis of Post-Traumatic Stress Disorder (PTSD): From Brain to Treatment
20. Effect of stress on neuronal cells: Morphological to molecular approach
