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Bone Growth Products Market - Focused Insights 2024-2029

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    Report

  • 146 Pages
  • October 2024
  • Region: Global
  • Arizton
  • ID: 6020045
1h Free Analyst Time
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The Bone Growth Products Market was valued at USD 1.09 billion in 2023, and is expected to reach USD 1.35 billion by 2029, rising at a CAGR of 3.72%.

MARKET OPPORTUNITIES & DRIVERS

The Rise of Self-Powered Implantable Devices

Invasive bone growth stimulators are implantable devices that supply electrical energy to non-healing fractures or bone fusion sites, aiming to induce bone formation, stimulate growth, and promote healing. These devices, which use direct current delivered via an implanted lead, offer a consistent current to the fracture site, overcoming issues related to patient compliance seen in non-invasive systems. Invasive stimulators are particularly indicated for non-unions of the tibia, femur, and humerus and have proven effective for high-risk individuals undergoing lumbar or sacral fusion, including those with a history of fusion failure or conditions such as smoking, obesity, or diabetes. Bone, being a piezoelectric material, generates a small electrical charge under strain, which aids in healing. The growing advantages of these devices suggest increased adoption in developed countries, with ongoing research to enhance their market presence and efficacy.

Impact of Bone Morphogenetic Proteins (BMPs) in Spinal Fusion and Bone Regeneration

Bone morphogenetic proteins (BMPs), part of the transforming growth factor-beta (TGF-beta) family, have become a promising alternative to autologous bone grafts, especially in spinal fusion and bone regeneration. Approved by the FDA in 2002 for anterior lumbar fusion, BMPs aim to enhance bone healing with fewer complications than traditional grafting methods. They have shown high effectiveness, with fusion rates of 98% compared to 76% for iliac crest grafts (ICBGs), and are used in various spinal fusion techniques, including interbody, posterolateral, and circumferential fusion. BMPs are comparable to ICBGs in safety and efficacy and are expanding into off-label uses, such as posterior spinal fusion and cervical fusion. BMPs, alongside other biological factors like FGF, PDGF, and IGF, play a significant role in advancing bone regeneration. While autologous grafts remain the standard in orthopedic procedures, BMPs offer a well-researched, effective alternative.

The Rising Adoption of Biocompatible Synthetic Bone Grafts and Biologics

The growing use of biocompatible synthetic bone grafts and biologics is a key driver of the bone growth products market. Synthetic grafts, made from materials like ceramics, polymers, and composites, mimic natural bone structure, providing scaffolds for new bone growth while reducing disease transmission and immune rejection risks associated with allografts and autografts. These grafts are especially in demand for spinal fusion surgeries and trauma cases. Biologics, such as bone morphogenetic proteins (BMPs) and platelet-rich plasma (PRP), enhance natural bone healing by promoting cellular activity and bone growth. BMPs induce bone formation, improving outcomes in complex fractures, while PRP accelerates healing. These innovations are transforming the treatment of bone injuries, offering more effective, efficient, and personalized solutions, driving market growth as healthcare providers seek safer, cost-effective options.

INDUSTRY RESTRAINTS

Keeping Up with Rapid Technical Advancements

Bone growth stimulators are expensive and often not covered by insurance, leading many to seek affordable alternatives like physiotherapy, Ayurveda, and chiropractic care, especially in developing countries with high out-of-pocket costs. Due to their cost-effectiveness, these alternatives are popular in regions like Japan, China, and India. Additionally, discomfort from bone stimulators and a shortage of orthopedic surgeons drive patients toward traditional treatments. Expanding awareness, improving treatment access, and increasing insurance coverage could boost the adoption of bone growth products in low- and middle-income areas.

SEGMENTATION INSIGHTS

INSIGHTS BY PRODUCT

The global bone growth products market by product is segmented into bone growth stimulator devices, bone morphogenetic protein, and platelet-rich plasma. The bone growth stimulator devices segment accounted for the largest market share. Bone healing is a natural process, with the body continually replacing old bone with new. While fractures generally heal with appropriate treatments like casts, realignment, and surgery, complications such as delayed healing or non-union can occur. To address these issues, medical professionals seek ways to enhance and accelerate bone healing. Bone stimulators are designed to support this healing process and come in various forms, including electrical and ultrasonic stimulators. This segment dominates the market due to many patients preferring non-invasive or minimally invasive treatments to avoid surgical risks and long recovery periods. Bone growth stimulators, which can be used externally or with minimal intervention, align with this growing patient preference.

By Product

  • Bone Growth Stimulator Devices
  • Bone Morphogenetic Protein
  • Platelet Rich Plasma

INSIGHTS BY APPLICATION

The global bone growth products market by application is categorized into spinal fusion surgeries, oral & maxillofacial surgeries, delayed union & non-union bone fractures, and others. The spinal fusion surgeries show the highest growth during the forecast period. Bone Growth Stimulation (BGS) is a therapeutic technique commonly prescribed by surgeons following spinal fusion procedures to enhance the healing of bones in the spine. A bone growth stimulator is often used for patients undergoing cervical (neck) or lumbar (low back) spine surgeries to promote spinal fusion. This device helps to improve bone healing by stimulating growth and is particularly beneficial in cases where the fusion process is delayed or fails. Studies have shown that BGS significantly enhances fusion outcomes in both cervical and lumbar regions, making it a popular choice for post-operative treatment, thus helping segmental growth.

By Application

  • Spinal Fusion Surgeries
  • Oral & Maxillofacial Surgeries
  • Delayed Union & Non-union Bone Fractures
  • Others

INSIGHTS BY END-USER

Based on the end-user, the hospitals & clinics segment holds the largest global bone growth products market share. Hospitals serve as the primary point of care for bone-related issues, often investing in advanced technologies and materials to improve treatment outcomes. However, only larger multispecialty and Tier-I hospitals provide cutting-edge treatments such as bone morphogenetic proteins (BMP) and platelet-rich plasma (PRP). This is due to the complexity and cost of these therapies. Increasing patient awareness and improved insurance coverage have fueled the demand for advanced treatments, including bone stimulators, BMP, and PRP, which are particularly effective for treating difficult fractures like non-union fractures. Physician offices and clinics, especially in remote areas, are many patients' first point of contact. While these facilities may not be able to offer advanced treatments, they play a crucial role in referring patients to larger, specialized hospitals, which are helping the market grow.

By End-User

  • Hospitals & Clinics
  • Specialty Orthopedic & Spine Centers
  • Ambulatory Surgical Centers (ASCs)

GEOGRAPHICAL ANALYSIS

North America accounted for the largest global bone growth products market share, followed by Europe. The U.S. remains a major revenue contributor in North America due to the high penetration of spinal fusion procedures and a considerable volume of spinal fusion and non-fusion surgeries. The increasing prevalence of orthopedic diseases, accidental injuries, and the aging population primarily drive the growth. The availability of advanced, safer, and minimally invasive surgical treatments and ongoing technological innovations further support market expansion.

In Europe, Germany, France, the UK, Italy, and Spain are the primary revenue contributors to the global bone growth products market. This region benefits from a well-established and sophisticated healthcare infrastructure, providing access to advanced medical services, including spinal fusion and non-fusion procedures. The market's growth is driven by the increasing prevalence of bone disorders and the availability of reimbursement coverage for spinal fusion surgeries across many European countries.

By Geography

  • North America
    • The U.S.
    • Canada
  • Europe
    • Germany
    • France
    • UK
    • Italy
    • Spain
  • APAC
    • China
    • Japan
    • India
    • Australia
    • South Korea
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East & Africa
    • Turkey
    • Saudi Arabia
    • South Africa

COMPETITIVE LANDSCAPE

The global bone growth products market report includes exclusive data on 30 vendors. The market is highly competitive, with global players like Medtronic, Johnson & Johnson, Stryker, and Zimmer Biomet leading through acquisitions, collaborations, and new product launches. Small and mid-sized companies increasingly enter the market, focusing on novel, cost-effective products. There is a growing emphasis on developing advanced bone healing therapies, such as pulsed electromagnetic field therapies, to address challenges in bone regeneration, especially for elderly and diabetic patients. Key players like Bioventus, Orthofix, and Terumo are enhancing their product portfolios with innovative solutions.

Key vendors

  • Bioventus
  • Enovis Corp
  • Johnson & Johnson
  • Medtronic
  • Orthofix
  • Stryker Corp
  • Zimmer Biomet

Other Prominent Vendors

  • Altis Biologics
  • Bio-Dynamic Technologies
  • BTT Health
  • Cellumed
  • Elizur
  • EmCyte
  • Fintek Bio-Electric
  • IGEA
  • ITO
  • Kinex Medical
  • Ossatec Benelux
  • Pain Rehab Products
  • Royal Biologics
  • Fujifilm Corp
  • Smith & Nephew
  • Specialized Orthopedic Solutions
  • Stimulate Health
  • Terumo
  • Globus Medical
  • ATEC
  • Moximed
  • Anika Therapeutics
  • Highridge Medical

KEY QUESTIONS ANSWERED

1. How big is the global bone growth products market?
2. What Is the growth rate of the global bone growth products market?
3. Which region dominates the global bone growth products market?
4. Who are the major players in the global bone growth products market?
5. What are the key drivers of the global bone growth products market?

Table of Contents

Chapter - 1: Bone Growth Products Market Overview
  • Executive Summary
  • Key Findings
Chapter - 2: Bone Growth Products Market
Global: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
Chapter - 3: Bone Growth Products Market Segmentation Data
Global: Projected Revenue by Product (2020-2029; $Millions)
  • Bone Growth Stimulator Devices
  • Bone Morphogenetic Protein
  • Platelet Rich Plasma
Global: Projected Revenue by Application (2020-2029; $Millions)
  • Spinal Fusion Surgeries
  • Oral & Maxillofacial Surgeries
  • Delayed Union & Non-Union Bone Fractures
  • Others
Global: Projected Revenue by End-user (2020-2029; $Millions)
  • Hospitals & Clinics
  • Specialty Orthopedic & Spine Centers
  • Ambulatory Surgical Centers (Ascs)
Chapter - 4: Key Regions Overview
North America: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in US
  • Projected Revenue of Bone Growth Products Market in Canada
Europe: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Germany
  • Projected Revenue of Bone Growth Products Market in France
  • Projected Revenue of Bone Growth Products Market in UK
  • Projected Revenue of Bone Growth Products Market in Italy
  • Projected Revenue of Bone Growth Products Market in Spain
APAC: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in China
  • Projected Revenue of Bone Growth Products Market in Japan
  • Projected Revenue of Bone Growth Products Market in India
  • Projected Revenue of Bone Growth Products Market in Australia
  • Projected Revenue of Bone Growth Products Market in South Korea
Latin America: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Brazil
  • Projected Revenue of Bone Growth Products Market in Mexico
  • Projected Revenue of Bone Growth Products Market in Argentina
Middle East & Africa: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Turkey
  • Projected Revenue of Bone Growth Products Market in Saudi Arabia
  • Projected Revenue of Bone Growth Products Market in South Africa
Chapter - 5: Bone Growth Products Market Prospects & Opportunities
  • Bone Growth Products Market Opportunities & Trends
  • Bone Growth Products Market Drivers
  • Bone Growth Products Market Constraints
Chapter - 6: Bone Growth Products Industry Overview
  • Bone Growth Products Market - Competitive Landscape
  • Bone Growth Products Market - Key Vendor Profiles
  • Bone Growth Products Market - Other Prominent Vendors
  • Bone Growth Products Market - Key Strategic Recommendations
Chapter - 7: Appendix
  • Research Methodology
  • Abbreviations
  • About the Analyst
List of Exhibits
Exhibit 1: Projected Revenues of Global Bone Growth Products (2020-2029, $ Mn)
Exhibit 2: Market Size & Forecast - Bone Growth Stimulator Devices (2020-2029, $ Mn)
Exhibit 3: Market Size & Forecast - Bone Morphogenetic Protein (2020-2029, $ Mn)
Exhibit 4: Market Size & Forecast - Platelet Rich Plasma (2020-2029, $ Mn)
Exhibit 5: Market Size & Forecast - Spinal Fusion Surgeries (2020-2029, $ Mn)
Exhibit 6: Market Size & Forecast - Oral & Maxillofacial Surgeries (2020-2029, $ Mn)
Exhibit 7: Market Size & Forecast - Delayed Union & Non-Union Bone Fractures (2020-2029, $ Mn)
Exhibit 8: Market Size & Forecast - Others (2020-2029, $ Mn)
Exhibit 9: Market Size & Forecast - Hospitals & Clinics (2020-2029, $ Mn)
Exhibit 10: Market Size & Forecast - Specialty Orthopedic & Spine Centers (2020-2029, $ Mn)
Exhibit 11: Market Size & Forecast - Ambulatory Surgical Centers (Ascs) (2020-2029, $ Mn)
Exhibit 12: Projected Revenues of Bone Growth Products in North America (2020-2029, $ Mn)
Exhibit 13: Projected Revenues of Bone Growth Products in the US (2020-2029, $ Mn)
Exhibit 14: Projected Revenues of Bone Growth Products in Canada (2020-2029, $ Mn)
Exhibit 15: Projected Revenues of Bone Growth Products in Europe (2020-2029, $ Mn)
Exhibit 16: Projected Revenues of Bone Growth Products in Germany (2020-2029, $ Mn)
Exhibit 17: Projected Revenues of Bone Growth Products in France (2020-2029, $ Mn)
Exhibit 18: Projected Revenues of Bone Growth Products in the UK (2020-2029, $ Mn)
Exhibit 19: Projected Revenues of Bone Growth Products in Italy (2020-2029, $ Mn)
Exhibit 20: Projected Revenues of Bone Growth Products in Spain (2020-2029, $ Mn)
Exhibit 21: Projected Revenues of Bone Growth Products in APAC (2020-2029, $ Mn)
Exhibit 22: Projected Revenues of Bone Growth Products in China (2020-2029, $ Mn)
Exhibit 23: Projected Revenues of Bone Growth Products in Japan (2020-2029, $ Mn)
Exhibit 24: Projected Revenues of Bone Growth Products in India (2020-2029, $ Mn)
Exhibit 25: Projected Revenues of Bone Growth Products in Australia (2020-2029, $ Mn)
Exhibit 26: Projected Revenues of Bone Growth Products in South Korea (2020-2029, $ Mn)
Exhibit 27: Projected Revenues of Bone Growth Products in Latin America (2020-2029, $ Mn)
Exhibit 28: Projected Revenues of Bone Growth Products in Brazil (2020-2029, $ Mn)
Exhibit 29: Projected Revenues of Bone Growth Products in Mexico (2020-2029, $ Mn)
Exhibit 30: Projected Revenues of Bone Growth Products in Argentina (2020-2029, $ Mn)
Exhibit 31: Projected Revenues of Bone Growth Products in the MEA (2020-2029, $ Mn)
Exhibit 32: Projected Revenues of Bone Growth Products in Turkey (2020-2029, $ Mn)
Exhibit 33: Projected Revenues of Bone Growth Products in Saudi Arabia (2020-2029, $ Mn)
Exhibit 34: Projected Revenues of Bone Growth Products in South Africa (2020-2029, $ Mn)
List of Tables
Table 1: Projected Revenues of Global Bone Growth Products Market (2020-2029, $ Mn)
Table 2: Global Bone Growth Products Market by Product (2020-2029, %)
Table 3: Global Bone Growth Products Market by Product (2020-2029, $ Mn)
Table 4: Global Bone Growth Products Market by Application (2020-2029, %)
Table 5: Global Bone Growth Products Market by Application (2020-2029, $ Mn)
Table 6: Global Bone Growth Products Market by End-user (2020-2029, %)
Table 7: Global Bone Growth Products Market by End-user (2020-2029, $ Mn)
Table 8: Global Bone Growth Products Market by Geography (2020-2029, %)
Table 9: Global Bone Growth Products Market by Geography (2020-2029, $ Mn)

Companies Mentioned

  • Bioventus
  • Enovis Corp
  • Johnson & Johnson
  • Medtronic
  • Orthofix
  • Stryker Corp
  • Zimmer Biomet
  • Altis Biologics
  • Bio-Dynamic Technologies
  • BTT Health
  • Cellumed
  • Elizur
  • EmCyte
  • Fintek Bio-Electric
  • IGEA
  • ITO
  • Kinex Medical
  • Ossatec Benelux
  • Pain Rehab Products
  • Royal Biologics
  • Fujifilm Corp
  • Smith & Nephew
  • Specialized Orthopedic Solutions
  • Stimulate Health
  • Terumo
  • Globus Medical
  • ATEC
  • Moximed
  • Anika Therapeutics
  • Highridge Medical

Methodology


Our research comprises a mix of primary and secondary research. The secondary research sources that are typically referred to include, but are not limited to, company websites, annual reports, financial reports, company pipeline charts, broker reports, investor presentations and SEC filings, journals and conferences, internal proprietary databases, news articles, press releases, and webcasts specific to the companies operating in any given market.

Primary research involves email interactions with the industry participants across major geographies. The participants who typically take part in such a process include, but are not limited to, CEOs, VPs, business development managers, market intelligence managers, and national sales managers. We primarily rely on internal research work and internal databases that we have populated over the years. We cross-verify our secondary research findings with the primary respondents participating in the study.



 

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