Comprehensive resource exploring a unique chemical transformation that generates new compounds with diverse properties for modern organic synthesis research
Denitrogenative Transformation of Nitrogen Heterocycles explores all 10 polynitrogen heterocycles that are known to undergo denitrogenative transformations to date. Following highlights on the remarkable modifications encountered in the synthesis of nitrogen heterocycles, the chapters use a reaction-based approach to explain denitrogenative transformations in detail.
This book covers the exponential growth in scientific literature in the last few decades for denitrogenative reactions of polynitrogen heterocycles which play a key role in natural products, medicinal chemistry, pharmaceuticals, biochemistry, and material sciences. This book also discusses denitrogenative cascade reactions, which accomplish powerful transformations from simple polynitrogen heterocycles to more complex molecules in modern synthetic chemistry.
Written by a highly qualified academic with significant experience in the field, Denitrogenative Transformation of Nitrogen Heterocycles covers sample topics including: - Transannulation of N-sulfonyl-1,2,3-triazoles with polar multiple bonds such as carbonyls and nitriles and non-polar multiple bonds such as alkenes, alkynes, and allenes- Insertion of azavinyl carbenes to C-X/X-X bond, denitrogenative rearrangements of N-sulfonyl-1,2,3-triazoles, and denitrogenative transformations of NH- and N-fluoroalkyl-1,2,3-triazoles- Metal-catalyzed and metal-free denitrogenative transformations of pyridotriazoles and denitrogenative transannulation of benzotriazoles and thiadiazoles- Denitrogenative transformations of tetrazoles and radical denitrogenative transformations of polynitrogen heterocycles
The first book of its kind on the subject, Denitrogenative Transformation of Nitrogen Heterocycles is an essential reference for researchers and scientists working in organic chemistry, organometallic chemistry, and transition metal catalysis, as well as academics and industry professionals in related fields.
Denitrogenative Transformation of Nitrogen Heterocycles explores all 10 polynitrogen heterocycles that are known to undergo denitrogenative transformations to date. Following highlights on the remarkable modifications encountered in the synthesis of nitrogen heterocycles, the chapters use a reaction-based approach to explain denitrogenative transformations in detail.
This book covers the exponential growth in scientific literature in the last few decades for denitrogenative reactions of polynitrogen heterocycles which play a key role in natural products, medicinal chemistry, pharmaceuticals, biochemistry, and material sciences. This book also discusses denitrogenative cascade reactions, which accomplish powerful transformations from simple polynitrogen heterocycles to more complex molecules in modern synthetic chemistry.
Written by a highly qualified academic with significant experience in the field, Denitrogenative Transformation of Nitrogen Heterocycles covers sample topics including: - Transannulation of N-sulfonyl-1,2,3-triazoles with polar multiple bonds such as carbonyls and nitriles and non-polar multiple bonds such as alkenes, alkynes, and allenes- Insertion of azavinyl carbenes to C-X/X-X bond, denitrogenative rearrangements of N-sulfonyl-1,2,3-triazoles, and denitrogenative transformations of NH- and N-fluoroalkyl-1,2,3-triazoles- Metal-catalyzed and metal-free denitrogenative transformations of pyridotriazoles and denitrogenative transannulation of benzotriazoles and thiadiazoles- Denitrogenative transformations of tetrazoles and radical denitrogenative transformations of polynitrogen heterocycles
The first book of its kind on the subject, Denitrogenative Transformation of Nitrogen Heterocycles is an essential reference for researchers and scientists working in organic chemistry, organometallic chemistry, and transition metal catalysis, as well as academics and industry professionals in related fields.
Table of Contents
1. Introduction: Denitrogenative Transformations2. Synthesis of N-sulfonyl-1,2,3-triazoles and related compounds
3. Transannulation of N-sulfonyl-1,2,3-triazoles with non-polar multiple bonds such as alkenes, alkynes and allenes
4. Transannulation of N-sulfonyl-1,2,3-triazoles with polar multiple bonds such as carbonyls and nitriles
5. Transannulations of N-sulfonyl-1,2,3-triazoles with Carbo/Heterocycles
6. Insertion of azavinyl carbenes to C?H/X?H bond
7. Insertion of azavinyl carbenes to C?X/X?X bond
8. Denitrogenative rearrangements of N-sulfonyl-1,2,3-triazoles
9. Denitrogenative transformations of N-trifluoromethyl-1,2,3-triazoles
10. Denitrogenative transformations of 5-iodo-1,2,3-triazoles
11. Asymmetric perspective on denitrogenative transformation of 1,2,3-triazoles
12. Denitrogenative transformations of triazoloindoles
13. Metal-catalyzed denitrogenative transformations of pyridotriazoles
14. Metal-free denitrogenative transformations of pyridotriazoles
15. Denitrogenative C?C/C?X bond formation of benzotriazoles
16. Denitrogenative transannulation of benzotriazoles
17. Denitrogenative transannulation of thiadiazoles
18. Denitrogenative transformations of benzotriazinones and related compounds
19. Denitrogenative transformations of 3-aminoindazoles
20. Denitrogenative transformations of tetrazoles
21. Denitrogenative transformations of pyridotetrazoles
22. Radical denitrogenative transformations of polynitrogen heterocycles
23. Application of denitrogenative transformations in synthesis of natural products
