Clinical Biochemistry of Domestic Animals, Seventh Edition cements this book's position as a standard text in its field, covering all aspects of biochemical abnormalities in domestic animals caused by various diseases. Here, across more than thirty chapters, leading researchers and pathologists provide accessible overviews and in-depth analysis of biochemical changes in the blood, urine, cerebrospinal fluid, joint fluids, other body fluids, and in cells impacting the health of domestic animals. Readers gain a full and nuanced understanding of biochemical changes underlying disease processes and learn to apply knowledge towards diagnosis and treatment. This new edition has been updated to address recent advances in the field, with all-new chapters on evolving technologies, big data approaches in research and clinical practice, clinical pathology profiles, translational biomarkers and biomarker validation, exotic animals, myocardial function, and tissue and body fluid biochemistry.
Table of Contents
1. Modern Technology and Methodology (incl QC) 2. The clinical pathology profile 3. Translational Biomarkers
definition, characteristics, with a few classic examples of effective ones pancreatic lipase, cTnI, GLD, fructosamine, antioxidants and oxidative stress 5. Big Data 6. Allometry and adaptation and exotic animals 7. Diagnostic Enzymology of Domestic Animals 8. Fluid, Electrolyte, and Acid-Base Balance 9. Proteins, Proteomics, and the Dysproteinemias 10. Lipids and Ketones 11. Carbohydrate Metabolism and Its Diseases 12. Porphyrins and the Porphyrias 13. Iron Metabolism and Its Disorders 14. Trace Minerals 15. Vitamins 16. Clinical Biochemistry in Toxicology 17. Preclinical, Toxicologic, Clinical Biochemistry 18. Hepatic Function 19. Kidney Function and Damage 20. Gastrointestinal Function 21. Thyroid Function 22. Adrenocortical Function 23. Pituitary Function 24. Clinical Reproductive Endocrinology 25. Myocardial Function 26. Skeletal Muscle Function 27. The Erythrocyte: Physiology, Metabolism, and Biochemical Disorders 28. Hemostasis 29. Neutrophil Function 30. Clinical Veterinary Immunology 31. Tissue and Body Fluid Biochemistry 32. Concepts of Normality in Clinical Biochemistry 33. Comparative Medical Genetics 34. Lysosomal Storage Diseases 35. Tumor Markers 36. Cerebrospinal Fluid 37. Avian Clinical Biochemistry
Authors
Peter J O'Brien Lecturer, Assistant Professor, Department of Clinical Pathology, School of Veterinary Medicine, University College, Dublin, Ireland.
Dr. Peter O'Brien obtained his MS and PhD (Major of Veterinary Physiology and Pharmacology, Minor of Biochemistry) in Minnesota, USA, then his board certification and DVSc in Veterinary Clinical Pathology in Guelph, Canada, where he served on faculty for 7 years as a Canadian Heart and Stroke Foundation Scholar and as Associate Professor of Clinical Pathology. Dr. O'Brien has published over 150 scientific papers and is most well-known for development of tests for susceptibility to malignant hyperthermia and for occurrence of myocardial injury, and for in vitro, animal-alternative tests for predicting human hepatotoxicity. Peter served on the executive board and as President for the: European Society of Veterinary Clinical Pathology, European College of Veterinary Clinical Pathology, and European Board of Veterinary Specialization. He is scientific secretary and conference organizer for the Association of Comparative Clinical Pathology.
Joy Archer Senior Lecturer, Clinical Pathology; the Queen's Veterinary School Hospital, University of Cambridge, UK.
After gaining masters and PhD degrees in biochemistry followed by post-doctoral research experience, Dr. Joy Archer spent many years doing laboratory and animal based medical research and teaching biochemistry to medical students. When Joy changed profession to veterinary medicine, she chose to specialize in clinical pathology and pathology as they are laboratory medicine-based specialisms. Joy's academic positions have involved teaching veterinary and graduate students, diagnostic services, laboratory management and clinical related research. Joy was a founding Diplomate of European College of Veterinary Clinical Pathology (ECVCP) and a past president of the ECVCP. In 2013, she was awarded honorary Fellowship of the Royal College of Veterinary Surgeons, and in 2015 she was awarded the European Society for Veterinary Clinical Pathology Hall of Fame Award, both for her services to Veterinary Clinical Pathology.
Saverio Paltrinieri Full Professor, Pathology, Department of Veterinary Medicine (Dimevet), University of Milan Universit� degli Studi di Milano, Milano, Italy.
Dr. Saverio Paltrinieri is a Full Professor of Pathology at the Department of Veterinary Medicine (Dimevet), University of Milan Universit� degli Studi di Milano, Milano, Italy. Dr. Paltrinieri holds a PhD in Comparative Pathology of Domestic and Wild Animal, where he completed applied research on inflammation and metabolic diseases of ruminants. At University of Milan he teaches veterinary general pathology, pathophysiology, clinical pathology, manages a research laboratory Management in applied diagnostics; and is Director of the veterinary clinical husbandry center. He is a member of various journal editorial boards and professional and scientific organizations.
Zoe S. Polizopoulou Professor, Faculty of Veterinary Medicine,?Aristotle University of Thessaloniki, Greece.
Dr. Zoe S. Polizopoulou is a Professor within the Faculty of Veterinary Medicine, at the Aristotle University of Thessaloniki, Greece. She is a member of European College of Veterinary Clinical Pathology, and the European Society of Animal Veterinarians. Dr. Polizopoulou has published widely in such peer reviewed journals as the Journal of the American Animal Hospital Association, Veterinary Parasitology, Research in Veterinary Science, Veterinary Clinical Pathology, and the Journal of Comparative Pathology.
Jose Joaquin Ceron Full Professor, Murcia University Veterinary School, Murcia, Spain.
Dr. Jose Joaquin Cer�n is now a Full Professor at Murcia University Veterinary School and Diplomate of the European College of Veterinary Clinical Pathology. He is also the leader of a research group INTERLAB-UMU, which has been accredited as a research group of excellence by the Autonomic Government of Murcia Region. This research group is focused in the development and study of new biomarkers to better evaluate health and welfare in both veterinary and human side with special emphasis of the use of non-invasive samples such as saliva. It is an interdisciplinary group with multiple collaborators both in the human and veterinary field. In addition to our research, INTERLAB-UMU provides analytical services and offers the new biomarkers that have developed to the UMU veterinary teaching hospital, external practitioners and private companies. This Laboratory is accredited by the Standard Committee of the European College of Veterinary Clinical Pathology and we recently received an award in 2016 by Murcia University for our activity of transferring knowledge to the private sector.
