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Neuroglia in Neurologic and Psychiatric Disorders, Part II. Handbook of Clinical Neurology Volume 210

  • Book

  • June 2025
  • Elsevier Science and Technology
  • ID: 6035839
Neuroglia in Neurologic and Psychiatric Disorders, Part II discusses glia relative to neurologic and psychiatric disorders, emphasizing cross-disease-glial cell dysfunctions. Driven by advances in genetics, transcriptomics, electrophysiologic and imaging techniques, as well as by the increase in knowledge on neuropathologic features and underlying disease mechanisms, this book bridges the gap between neuroglia basic science and neuroglia clinical research.

Table of Contents

Part I. Glia in neurological disorders
1. General pathophysiology of neuroglia
2. Glia in neurodegeneration: Alzheimer’s, Parkinson’s and Huntington’s disease
3. Glia in neurodegeneration: amyotrophic lateral sclerosis and frontotemporal dementia
4. Glia in epilepsy
5. Glial cell pathology in genetic and epigenetic disorders of the central nervous system
6. Glia in stroke/cerebrovascular disease?
7. Unravelling the complexity of microglial responses in traumatic brain and spinal cord injury
8. Astrocytes and microglia in multiple sclerosis and neuromyelitis optica
9. Glia in autoimmune encephalitis
10. Glia in leukodystrophies
11. Reciprocal interactions between glioma and tissue-resident cells fueling tumor progression
12. Neuroglia in hepatic encephalopathy
13. Infectious diseases (including COVID-19)
14. Physiology and pathophysiology of the retinal neuroglia

Part II. Glia in psychiatric disorders
15. From womb to world: the interplay between maternal immune activation, glia and neurodevelopment
16. Neuroglia in mood disorders
17. Schizophrenia
18. Neuroglia in autism spectrum disorders
19. Glia in eating disorders (obesity, Prader-Willi syndrome, and anorexia nervosa)
20. Glia in tourette syndrome and obsessive-compulsive disorder
21. Glia in anxiety disorders
22. Glia in substance use disorders
23. Glia in suicide