Well-written, readable, and superbly illustrated, Cellular and Molecular Immunology, Eleventh Edition, continues the tradition of excellence established through multiple editions of this bestselling text. Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging information in this challenging area. It's an ideal resource for medical, graduate, and undergraduate students, as well as a trusted reference for physicians and scientists.
- Highlights the implications of immunologic science for the management of human disease, emphasizing clinical relevance throughout
- Employs a highly accessible writing style that makes difficult concepts easier to understand, and provides clear implications of immunologic science to the management of human disease and clinical practice
- Features updates from cover to cover, including new information on COVID-19, genetics and pathogenesis of allergic diseases, newly recognized primary immune regulatory disorders, interactions between the immune system and brain and their role in CNS disorders, and CRISPR/Cas9 based gene editing
- Provides a highly visual, full-color description of the key immunologic and molecular processes with a fully updated, comprehensive, and consistent art program, including many new and extensively revised illustrations
- Helps readers grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions
- Includes summary boxes that assist with rapid review and mastery of key material
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud
- Fully revised throughout - including new and expanded coverage of human immune system; neuroimmunology; cancer immunotherapy; intracellular sensors of innate immunity, therapeutic use of monoclonal antibodies, regulation of migration events during T cell-B cell interactions, regulatory and transcriptional events in germinal center formation, immunology of infectious diseases including coronaviruses, human immunodeficiency disorders, and immunology of HIV.
Table of Contents
1. Properties and Overview of Immune Responses2. Cells and Tissues of the Immune System
3. Leukocyte Circulation and Migration into Tissues
4. Innate Immunity
5. Antibodies and Antigens
6. Antigen Presentation to T Lymphocytes and the Functions of MHC Molecules
7. Immune Receptors and Signal Transduction
8. Lymphocyte Development and Antigen Receptor Gene Rearrangement
9. Activation of T Lymphocytes
10. Differentiation and Functions of CD4+ Effector T Cells
11. Differentiation and Functions of CD8+ Effector T Cells
12. B Cell Activation and Antibody Production
13. Effector Mechanisms of Humoral Immunity
14. Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
15. Immunologic Tolerance and Autoimmunity
16. Immunity to Microbes
17. Transplantation Immunology
18. Immunity to Tumors
19. Hypersensitivity Disorders
20. Allergy
21. Congenital and Acquired Immunodeficiencies
