Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous silicon nanomaterials, with a special emphasis on drug delivery. This book introduces the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, such as vaccine development, drug delivery, and tissue engineering. It also contains new insights on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, cancer immunotherapy, and more. Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers is of interest to researchers in the fields of materials science, nanotechnology, pharmaceutical science, biomedical engineering, and cancer research.
Table of Contents
1. Historical advancements in targeted nanoscale drug delivery systems2. Synthesis of Porous Silicon-based Nanoparticles
3. Characterization techniques for mesoporous silicon nanoparticles
4. Mesoporous silicon for solubility enhancement of drugs
5. Porous silicon-based nanocarriers for tumor targeting
6. Porous silicon and related composites for topical drug delivery
7. Porous silicon nanocarriers for the management of neurodegenerative disorders
8. Functionalized silica nanocarriers for brain targeted delivery
9. Porous silicon-based materials in nanoneedle and microneedle-based drug delivery systems
10. Porous silicon-based drug delivery carriers in cancer management
11. Stimuli-responsive silica nanoparticles: Smart systems for controlled drug delivery
12. Mesoporous silica-based nanocarriers in pulmonary drug delivery
13. Porous silicon nanoparticles for improved cellular uptake and targeted drug delivery
14. Recent advances in porous silicon-based technology for biomedical applications
15. Immunotherapeutic applications of porous silicon nanoparticles
16. Bioengineered porous silicon nanoparticles in vaccine development
17. Bioavailability enhancement of poorly soluble drugs with mesoporous silicon
18. Silica nanoparticles in clinical trials
19. Mesoporous silica nanoparticles for therapeutic uses: from bench to clinics
20. Future perspectives of mesoporous silica-based nanocarriers in drug delivery
Authors
Rajendra Awasthi Professor, Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India.Rajendra Awasthi is Professor of Pharmaceutics at Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India.
Santosh Kumar Singh Senior Scientist, Centre of Experimental Medicine and Surgery (CEMS), Faculty of Medicine, Institute of Medical Sciences, Banaras Hindu University, India.Santosh Kumar Singh is a Senior Scientist at the Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Anurag Kumar Singh Research Associate, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, India.Anurag Kumar Singh is a Research Associate in Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, India.
