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The Immunology of the Domestic Ruminants. Cattle, Sheep, and Goats

  • Book

  • May 2025
  • Elsevier Science and Technology
  • ID: 6042233
The Immunology of Domestic Ruminants: Cattle, Sheep, and Goats provides a thorough examination of the immune systems of these animals. It explores their normal immune functions and their roles in combating infectious and parasitic diseases, chronic inflammatory conditions, and immunodeficiency disorders. The book incorporates new data from the bovine genome project and highlights significant breed differences. Both innate and adaptive immunity are systematically covered, offering insights into basic and applied aspects of bovine immunology. In addition to detailing the immunology of major bacterial, viral, and parasitic diseases in cattle, the book reviews bovine vaccines and emphasizes the importance nutrition.

This essential resource caters to professionals in large animal research and practice, providing comprehensive information on the immunology of domestic cattle, sheep, and goats.

Table of Contents

1. The evolution and domestication of the ruminants
2. Bovine ontogeny, reproduction, and lactation
3. Innate immunity in cattle and other ruminants
4. The ruminant sickness response
5. Bovine leukocytes and erythrocytes
6. Bovine cytokines and chemokines
7. Bovine antigen processing cells: dendritic cells and macrophages
8. The bovine lymphoid system
9. BoLA: The bovine Major Histocompatibility Complex
10. Bovine innate lymphoid cells
11. Ruminant humoral immunity
12. Ruminant T cell responses
13. Immunity on ruminant body surfaces
14. The rumen and the intestinal microbiota
15. Immunity in the mammary gland
16. Bovine vaccines
17. Selected bovine bacterial diseases
18. Selected bovine viral diseases
19. Immunity to selected bovine parasites
20. Ruminant anaphylaxis and allergic diseases
21. Ruminant hypersensitivity diseases
22. Ruminant immunodeficiency diseases
23. Nutrition and the ruminant immune system
24. Aspects of immunity in the sheep
25. Aspects of immunity in the goat

Authors

Ian R. Tizard University Distinguished Professor of Immunology Emeritus, Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.

Ian R. Tizard, BVMS, BSc, PhD, DSc (Hons), DACVM, is a Diplomate of the American College of Veterinary Microbiologists and a University Distinguished Professor Emeritus of Immunology, Department of Veterinary Pathobiology, The Texas Veterinary Medical Center at Texas A &M University (TAMU), College Station, Texas, USA. Dr. Tizard earned his Bachelor of Veterinary Medicine and Surgery from the University of Edinburgh, Scotland, in 1965. He then completed a Bachelor of Science in Pathology and a PhD in Immunology. After completing his studies, Dr. Tizard became a Post-Doctoral Fellow at the University of Guelph, where he remained as a professor until 1982 when he moved to TAMU. Dr. Tizard wrote the first standardized textbook on Veterinary Immunology in 1977. This text, now in its 11th edition, is used worldwide, and has played a major role in establishing Immunology among the key disciplines.