Table of Contents
1. Chemotherapeutic drugs and its side effects, breast cancer biomarkers, detection, level of targeting and EPR effect2. Receptor-ligand based targeting approaches breast cancer
3. Stimuli-based targeting breast cancer
4. Advance strategies for targeting severe triple-negative breast cancer
5. Targeted therapy for BRCA gene mutations breast cancer
6. Androgen receptor targeted therapy for breast cancer
7. Monoclonal antibodies-based breast cancer targeting
8. Breast cancer stem cell targeting
9. The Role of Hormone Receptors in Breast Cancer: New opportunities for Treatment and Prevention
10. HER2-positive and HER2-negative Targeted Therapies
11. Immunotherapy for breast cancer
12. Current market formulation, therapy in clinical trails, and status of IPR for breast cancer
Authors
Pankaj Kumar Singh Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana 500037, India. Dr. Pankaj Kumar Singh, Ph.D., is an Assistant Professor in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education and Research-Hyderabad (NIPER-Hyderabad), India. He earned his Doctorate in Pharmaceutics from CSIR-Central Drug Research Institute, Lucknow. Dr. Singh is actively involved in various scientific and socially impactful projects funded by prestigious organizations, including TSCOST-DBT, CCRUM, DST, ICMR, and the Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India. Manish K. Chourasia CSIR-Central Drug Research, India.Dr. Manish K. Chourasia, is currently working as a Senior Principal Scientist in the Division of Pharmaceutics and Pharmacokinetics at CSIR-Central Drug Research Institute (CDRI), Lucknow, a premium drug research institute in India. He received his PhD in Pharmaceutical Sciences from Dr. Harisingh Gour University, Madhya Pradesh, India and carried out his post-doctoral studies at Department of Pharmacy, National University of Singapore, Singapore. Having acquired valuable experience in both industry and academia, he subsequently joined the role of a scientist at CSIR-CDRI almost two decades ago. He has played a significant role in advancing the field of nanoparticle-based drug delivery for breast cancer, aiming to enhance the therapeutic outcome. He has published 80+ scientific papers including high-impact journal reviews. He has supervised more than 50 MS students and PhD students.
Kamal Dua Senior Lecturer, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, NSW, Australia.Dr. Kamal Dua is a Senior Lecturer in the Discipline of Pharmacy at the Graduate School of Health, University of Technology Sydney (UTS), Australia. He has research experience of over many years in the field of drug delivery systems targeting inflammatory diseases. Dr. Dua researches in two complementary areas; drug delivery and immunology, specifically addressing how these disciplines can advance one another, helping the community to live longer and healthier. This is evidenced by his extensive publication record in reputed journals. Dr. Dua's research interests focus on harnessing the pharmaceutical potential of modulating critical regulators such as Interleukins and microRNAs and developing new and effective drug delivery formulations for the management of chronic airway diseases. He has published more than 80 research articles in peer-reviewed international journals and authored or co-authored four books. He is an active member of many national and international professional societies.
Sachin Kumar Singh Professor and head of Pharmaceutical Chemistry and Pharmaceutical Analysis, School of Pharmaceutical Sciences, Lovely Professional University, India.Dr. Sachin Kumar Singh, is working as professor and head of Pharmaceutical Chemistry and Pharmaceutical Analysis at School of Pharmaceutical Sciences, Lovely Professional University, India and visiting professor Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), School of Public Health, Faculty of Health, University of Technology Sydney, Australia. He has many years of teaching and research experience. Dr. Singh has published more than 350 research papers with cumulative impact of 1300, authored several books, and dozens of book chapters. He is also featured under top 2% scientists of world as per the list of 2021, published by Stanford University, USA.
Santosh Kumar Guru National Institute of Pharmaceutical Education and Research, India. Dr. Kumar Guru is currently at NIPER in Hyderabad. He holds a PhD in pharmaceutical science.His research group mainly focus on basic and applied drug discovery in cancer biology and on role of drug tolerant persistent cell and chemotherapy induced tumor dormancy in cancer. He explores the survival mechanism of these dormant tumors through Autophagy, epigenetic, RNA methylation, efferocytosis, ferroptosis, EMT and YAP/TAZ mechanism.
