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Upconversion Nanoparticles for Biomedical Applications. Woodhead Publishing Series in Biomaterials

  • Book

  • September 2025
  • Elsevier Science and Technology
  • ID: 6057654
Upconversion Nanoparticles for Biomedical Applications provides a comprehensive overview of the chemistry, properties, characterization, and emerging applications of lanthanide-doped upconversion nanoparticles (UCNPs), focusing on upconversion mechanisms, fluorescent properties, and biomedical applications. The emerging applications of UCNPs include cancer diagnostics and therapy, biosensing and bioassays, bioimaging, drug and gene delivery, cellular optogenetics, and the detection of small biomolecules and ions. The biocompatibility, biodegradability, bio-distribution, toxicity and regulatory considerations of upconversion are fully considered.

This book offers a unique reference resource for researchers, bringing together a global authorship to cover the fundamentals, state-of-the-art, current challenges, and future perspectives of upconversion nanoparticles.

Table of Contents

1. Upconversion Nanoparticles: Current Trends and Future Perspectives
2. Upconversion Mechanisms and Strategies for Architecting Highly Efficient Upconversion Nanoparticles
3. Synthesis Methods of Upconversion Nanoparticles
4. Colloidal Stability and Fluorescent Characteristics of Upconversion Nanoparticles
5. Physiochemical Characterizations of Upconversion Nanoparticles
6. Surface Engineering of Upconversion Nanoparticles via Functionalization and Bioconjugation
7. Functionalized Upconversion Nanoparticles for Cancer Diagnostics and Therapy
8. Functionalized Upconversion Nanoparticles for Biosensing and Bioassays
9. Functionalized Upconversion Nanoparticles for Bioimaging
10. Functionalized Upconversion Nanoparticles for Drug and Gene Delivery
11. Functionalized Upconversion Nanoparticles in Cellular Optogenetics
12. Functionalized Upconversion Nanoparticles for Treatment of Amyloid Diseases
13. Functionalized Upconversion Nanoparticles for Detection of Small Biomolecules and Ions
14. Nanocomposites, Nanohybrids and Heterostructures of Functionalized Upconversion Nanoparticles with Other Nanomaterials for Biomedical Applications
15. Biocompatibility, Biodegradability, Bio-distribution, Toxicity and Regulatory Challenges of Functionalized Upconversion Nanoparticles in Biomedical Field
16. The Future Potential of Functionalized Upconversion Nanoparticles in Biomedical and Clinical Settings for Diagnostic and Therapeutic Applications

Authors

Kalim Deshmukh Senior Researcher, New Technologies - Research Centre, University of West Bohemia, Czech Republic. Kalim Deshmukh is a Senior Researcher at the New Technologies-Research Centre, University of West Bohemia, Pilsen, Czech Republic. He has over 20 years of research experience working with various nanostructured materials, and polymeric materials, especially polymer blends, and nanocomposites for numerous applications. His research interest is mainly focused on the synthesis, characterization,
and evaluation of the structure-property relationships of different polymers reinforced with various nanofillers including metal and metal oxide nanoparticles, carbon allotropes, and novel 2D nanomaterials for energy storage, gas sensing and EMI shielding applications. Kevin D. Belfield College of Science and Liberal Arts, Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, USA.

Kevin D. Belfield is the Dean of the College of Science and Liberal Arts, and Distinguished Professor of Chemistry and Environmental Science at the New Jersey Institute of Technology, New Jersey, USA. He received his B.S. in Chemistry in 1982 from Rochester Institute of Technology and his Ph.D. in Chemistry from Syracuse University in 1988. After conducting research in polymer stabilization and degradation at Ciba-Geigy, he conducted research in the synthesis and characterization of functionalized polymers at SUNY College of Environmental Science and Forestry. A pioneer in two-photon absorbing materials and two-photon photochemistry, Belfield has systematically developed principles for the design of probes for in vivo multiphoton fluorescence imaging, photosensitizers for photodynamic cancer therapy, and reagents for two-photon induced photochemical activation. Belfield is also the Becton Dickinson Endowed Research Professor at NJIT, was elected Fellow of the American Association for the Advancement of Science in 2013, Fellow of the American Chemical Society in 2019, and Fellow of the Royal Society of Chemistry in 2022.

Chaudhery Mustansar Hussain Adjunct Professor & Director of Laboratories, New Jersey Institute of Technology (NJIT), Newark, NJ, USA.

Chaudhery Mustansar Hussain is an Adjunct Professor and Director of Laboratories at the New Jersey Institute of Technology (NJIT), Newark, NJ, USA. His research focuses on the applications of nanotechnology and advanced materials, environmental management, analytical chemistry, and other various industries. He is a prolific author and editor for Elsevier, the American Chemical Society, the Royal Society of Chemistry, John Wiley & Sons, CRC Press, and Springer.