+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

Peptide Antibiotics Market Opportunity, Growth Drivers, Industry Trend Analysis, and Forecast 2025-2034

  • PDF Icon

    Report

  • 130 Pages
  • February 2025
  • Region: Global
  • Global Market Insights
  • ID: 6060553
The Peptide Antibiotics Market was valued at USD 5.2 billion in 2024, and is projected to reach USD 8.4 billion by 2034, rising at a CAGR of 5%. The market is experiencing significant expansion due to the escalating threat of antimicrobial resistance (AMR), which has led to an urgent demand for advanced antibiotic solutions. With bacterial infections becoming increasingly resistant to conventional treatments, peptide antibiotics are emerging as a crucial alternative. These specialized antibiotics, including polymyxins and gramicidin, exhibit potent activity against multidrug-resistant (MDR) microbes, making them indispensable in combating resistant infections.

As healthcare systems worldwide grapple with rising cases of antibiotic resistance, pharmaceutical companies are focusing on research and development efforts to bring innovative peptide antibiotics to the market. The growing prevalence of hospital-acquired infections (HAIs) and bloodstream infections has further intensified the need for effective treatment options, driving investments in this segment.

The pipeline for new peptide-based treatments is expanding as major players in the pharmaceutical industry collaborate on novel drug formulations that enhance efficacy and minimize resistance risks. Additionally, increasing government initiatives to tackle AMR and funding for antibiotic research are playing a crucial role in shaping the growth trajectory of the market. The emphasis on next-generation antibiotics that provide targeted action with minimal side effects is fueling the development of peptide-based solutions, which are particularly useful in treating severe bacterial infections that no longer respond to traditional therapies.

The market is primarily categorized into ribosomal and non-ribosomal synthesized peptide antibiotics. In 2024, the non-ribosomal synthesized peptide antibiotics segment dominated the market, holding a valuation of USD 1.4 billion. These antibiotics, produced through non-ribosomal peptide synthetases (NRPSs), offer structural diversity and enhanced resistance to enzymatic degradation. Their ability to incorporate non-proteinogenic amino acids gives them superior antimicrobial properties, making them more effective in tackling highly resistant pathogens. As a result, non-ribosomal synthesized peptide antibiotics continue to be the preferred choice among healthcare providers and researchers striving for more durable and broad-spectrum antibacterial agents.

The peptide antibiotics market is segmented by application, with key focus areas including skin infections, hospital-acquired bacterial pneumonia, bloodstream infections, and other bacterial conditions. Skin infections emerged as the leading segment in 2024, accounting for a 33.7% share of the market. The increasing prevalence of conditions such as cellulitis, impetigo, and diabetic foot ulcers, along with a surge in chronic wounds and post-surgical infections, is fueling demand for these targeted antibiotics. Peptide antibiotics offer a more precise treatment approach with reduced systemic toxicity, making them highly effective for patients with underlying health conditions requiring prolonged antibacterial therapy.

North America remained the dominant regional market for peptide antibiotics, accounting for a 40.6% share in 2023. The United States, in particular, continues to drive growth in this sector, supported by a strong pharmaceutical research ecosystem, a well-established regulatory framework, and substantial healthcare spending. The presence of leading biotechnology and pharmaceutical firms in the U.S. fosters continuous innovation in antibiotic development. With the rise of AMR cases, the demand for new peptide antibiotics in the country is set to increase, providing more targeted and efficient treatment options that reduce the risk of antibiotic resistance.

Comprehensive Market Analysis and Forecast

  • Industry trends, key growth drivers, challenges, future opportunities, and regulatory landscape
  • Competitive landscape with Porter’s Five Forces and PESTEL analysis
  • Market size, segmentation, and regional forecasts
  • In-depth company profiles, business strategies, financial insights, and SWOT analysis

This product will be delivered within 2-4 business days.

Table of Contents

Chapter 1 Methodology and Scope
1.1 Market scope and definition
1.2 Research design
1.2.1 Research approach
1.2.2 Data collection methods
1.3 Base estimates and calculations
1.3.1 Base year calculation
1.3.2 Key trends for market estimation
1.4 Forecast model
1.5 Primary research and validation
1.5.1 Primary sources
1.5.2 Data mining sources
Chapter 2 Executive Summary
2.1 Industry 360° synopsis
Chapter 3 Industry Insights
3.1 Industry ecosystem analysis
3.2 Industry impact forces
3.2.1 Growth drivers
3.2.1.1 Increasing prevalence of multi-drug resistant (MDR) bacteria
3.2.1.2 Increasing incidence of acute and chronic infectious diseases
3.2.1.3 Technological advancements in peptide synthesis
3.2.2 Industry pitfalls and challenges
3.2.2.1 High production costs
3.2.2.2 Limited oral bioavailability
3.3 Growth potential analysis
3.4 Regulatory landscape
3.5 Pipeline analysis
3.6 Future market trends
3.7 Porter’s analysis
3.8 PESTEL analysis
Chapter 4 Competitive Landscape, 2024
4.1 Introduction
4.2 Company matrix analysis
4.3 Competitive analysis of major market players
4.4 Competitive positioning matrix
4.5 Strategy dashboard
Chapter 5 Market Estimates and Forecast, by Type, 2021-2034 ($ Mn)
5.1 Key trends
5.2 Ribosomal synthesized peptide antibiotics
5.3 Non-ribosomal synthesized peptide antibiotics
Chapter 6 Market Estimates and Forecast, by Indication, 2021-2034 ($ Mn)
6.1 Key trends
6.2 Skin infection
6.3 Hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP)
6.4 Blood stream infections
6.5 Other indications
Chapter 7 Market Estimates and Forecast, by Route of Administration, 2021-2034 ($ Mn)
7.1 Key trends
7.2 Injectable
7.3 Oral
7.4 Topical
7.5 Other routes of administration
Chapter 8 Market Estimates and Forecast, by Distribution Channel, 2021-2034 ($ Mn)
8.1 Key trends
8.2 Hospital pharmacies
8.3 Retail pharmacies
8.4 Online pharmacies
Chapter 9 Market Estimates and Forecast, by Region, 2021-2034 ($ Mn)
9.1 Key trends
9.2 North America
9.2.1 U.S.
9.2.2 Canada
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 France
9.3.4 Italy
9.3.5 Spain
9.3.6 Netherlands
9.4 Asia-Pacific
9.4.1 China
9.4.2 Japan
9.4.3 India
9.4.4 Australia
9.4.5 South Korea
9.5 Latin America
9.5.1 Brazil
9.5.2 Mexico
9.5.3 Argentina
9.6 Middle East and Africa
9.6.1 South Africa
9.6.2 Saudi Arabia
9.6.3 UAE
Chapter 10 Company Profiles
10.1 AbbVie
10.2 ANI Pharmaceuticals
10.3 Cumberland Pharmaceuticals
10.4 Eli Lilly and Company
10.5 GSK plc
10.6 JHP Pharmaceuticals
10.7 Merck
10.8 Monarch Pharmachem
10.9 Melinta Therapeutics
10.10 NPS Pharmaceuticals
10.11 Pfizer
10.12 Sanofi
10.13 Sandoz
10.14 Teva Pharmaceuticals
10.15 The Menarini Group
10.16 Xellia Pharmaceuticals

Companies Mentioned

The companies featured in this Peptide Antibiotics market report include:
  • AbbVie
  • ANI Pharmaceuticals
  • Cumberland Pharmaceuticals
  • Eli Lilly and Company
  • GSK plc
  • JHP Pharmaceuticals
  • Merck
  • Monarch Pharmachem
  • Melinta Therapeutics
  • NPS Pharmaceuticals
  • Pfizer
  • Sanofi
  • Sandoz
  • Teva Pharmaceuticals
  • The Menarini Group
  • Xellia Pharmaceuticals

Table Information