Folate Market Report 2025

This folate market report delivers an in-depth analysis of the market’s key characteristics, including size, growth potential, and segmentation. It provides a detailed breakdown of the market across major regions and leading countries, highlighting historical data and future growth projections. The report also examines the competitive landscape, market share insights, emerging trends, and strategic developments shaping the market.

The folate market size has grown strongly in recent years. It will grow from $2.49 billion in 2024 to $2.71 billion in 2025 at a compound annual growth rate (CAGR) of 8.8%. The growth in the historic period can be attributed to rising awareness of the health benefits of folate in preventing birth defects and supporting overall health, increasing consumption of fortified foods and dietary supplements containing folate, growing prevalence of conditions related to folate deficiency, such as neural tube defects and anemia, rising healthcare initiatives promoting folate supplementation among pregnant women and increasing research and clinical studies.

The folate market size is expected to see strong growth in the next few years. It will grow to $3.74 billion in 2029 at a compound annual growth rate (CAGR) of 8.4%. The growth in the forecast period can be attributed to growing demand for fortified foods and dietary supplements as part of preventive healthcare, increasing prevalence of chronic diseases that benefit from folate, such as cardiovascular diseases and certain cancers, rising awareness about the role of folate in mental health and cognitive function, expanding applications of folate in personalized nutrition and tailored health solutions and increasing government and healthcare initiatives promoting folate supplementation in public health programs. Major trends in the forecast period include enhanced fortification of foods with folate, including new and innovative products, growing market for personalized folate supplements tailored to individual health needs, advancements in technology for improved folate delivery and absorption in supplements, digital health tools to track.

The increasing demand for nutritional supplements is expected to drive the growth of the folate market in the future. Nutritional supplements are designed to provide essential nutrients that may be lacking or insufficient in an individual's diet. With consumers placing greater emphasis on health and wellness, the demand for dietary supplements, particularly those containing vital vitamins such as folate, is rising. Folate is crucial for preventing birth defects, supporting cell function, and lowering the risk of chronic diseases, making it a sought-after ingredient in prenatal vitamins and other health products. For example, Armor Proteines, a French manufacturer of nutritional and functional dairy ingredients, reported that in 2022, revenues from nutritional supplements in France reached $2.87 billion, representing a 3% increase from 2021. Consequently, the growing interest in nutritional supplements is fueling the expansion of the folate market.

Key companies in the folate market are focusing on developing innovative products, such as choline-enriched folate, to enhance the nutritional benefits of folate supplements, boost cognitive function, and support overall brain health. Choline-enriched folate is a dietary supplement or fortified product that combines folate (vitamin B9) with choline, a nutrient essential for brain function, liver health, and cellular membrane integrity. For instance, in June 2024, Balchem, a US-based manufacturer specializing in ingredients for human nutrition and health, introduced Optifolin+. This ingredient features patented L-5-methylfolate with 98% active methylating nutrients, offering seven times the methyl groups found in other folate products. It improves stability, solubility, shelf life, and performance, facilitating easier product development. Optifolin+ also supports DNA and RNA synthesis, red blood cell formation, brain health, and helps maintain healthy homocysteine levels.

In May 2023, Freminich, a Switzerland-based manufacturer of fragrances, flavors, and sensory ingredients, completed a merger with DSM for an undisclosed amount. This merger aims to establish a leading global partner in nutrition, beauty, and well-being by combining DSM's health and nutrition portfolio with Firmenich's fragrance, taste, and ingredient businesses. DSM, based in the Netherlands, is known for its health and nutrition products that use folate.

Major companies operating in the folate market are BASF SE, Merck KGaA, DSM Nutritional Products, Shandong Xinhua Pharmaceutical Co., Lincoln Pharmaceuticals Ltd., Nature's Bounty Co, Jiangxi Tianxin Pharmaceutical Co. Ltd., Zydus Cadila Healthcare Ltd., Jubilant Pharmova Ltd., Emcure Pharmaceuticals Ltd., Pharmavite LLC, Niutang Chemical Plant Co. Ltd., Gemini Pharmaceuticals Inc., Synokem Pharmaceuticals Ltd., ITM Isotope Technologies Munich SE, NattoPharma ASA, D.S. Lab, Gnosis by Lesaffre, Gnosis SPA, AIE Pharmaceuticals Inc., Hebei Jiheng Group Pharmacy Co. Ltd., Seidler Chemical Co. Inc., Superior Supplement Manufacturing.

North America was the largest region in the Folate market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the folate market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the folate market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Folate, or vitamin B9, is a water-soluble B vitamin essential for DNA synthesis, cell division, and healthy fetal development during pregnancy. It is naturally found in leafy green vegetables, legumes, and citrus fruits. Additionally, folate is available in its synthetic form as folic acid in dietary supplements and fortified foods, which helps prevent deficiencies and supports overall health.

The primary types of folate are 5-methyltetrahydrofolate (MTHF) calcium salt and 5-methyltetrahydrofolate (MTHF) glucosamine salt. MTHF calcium salt is a biologically active form of folate with high bioavailability, making it easily absorbable and usable by the body without needing conversion from folic acid. Folate is sourced from various foods, including fruits, milk, green vegetables, liver, and seafood, and is available in forms such as tablets, capsules, powders, lozenges, gummies, and more. It is used across the food industry, nutraceuticals, and pharmaceuticals, catering to areas such as fortified foods, baby foods, and dietary supplements.

The folate market research report is one of a series of new reports that provides folate market statistics, including folate industry global market size, regional shares, competitors with a folate market share, detailed folate market segments, market trends, and opportunities, and any further data you may need to thrive in the folate industry. This folate market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The folate market consists of sales of folate supplements and pharmaceuticals containing folic acid or folate derivatives. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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