Achelios Therapeutics is a biopharmaceutical company that reformulates non-steroidal anti-inflammatory drug molecules for the treatment of pain and inflammation. Its best known products are TOPOFEN, a product for the indication of acute migraine, prophylactic migraine, osteoarthritis, and sprains and strains; and ACHETOGEL, a gel-based formulation that enables transdermal penetration of active ingredients to the target tissue. The company was founded in 2012 and is based in Chapel Hill, North Carolina.