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Gut Microbiota Market, By Product, By Application, By Disease Type, By End Users, By Distribution Channel: By Region - Market Size, Industry Dynamics, Opportunity Analysis and Forecast for 2024-2031

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    Report

  • 209 Pages
  • June 2024
  • Region: Global
  • Astute Analytica
  • ID: 5982819
UP TO OFF until Jan 31st 2025

Global Gut Microbiota Market Forecast till 2032:

Set to Reach US$ 2.94 Billion by 2031 with a CAGR of 23.80%

Market Introduction:

The Global Gut Microbiota Market is experiencing robust expansion, valued at US$ 0.58 billion in 2023 and projected to grow at a CAGR of 23.80% from 2024 to 2032.

The global gut microbiota market is an increasingly pivotal segment of the healthcare and biotechnology sectors, driven by a growing understanding of the vital role the gut microbiome plays in human health. This market focuses on products and technologies aimed at studying and modifying the diverse array of microorganisms in the human digestive tract, including bacteria, fungi, and viruses, which are essential for nutrient absorption, immune function, and overall well-being.

As research continues to reveal connections between gut microbiota and a range of health issues - from gastrointestinal disorders like irritable bowel syndrome and Crohn’s disease to systemic conditions such as diabetes, obesity, and even mental health disorders - interest in this field has surged. This has led to an expansion in the development and consumption of probiotics, prebiotics, and innovative microbiome therapeutics.

Key growth drivers include advances in genomics and biotechnology that enhance our ability to analyze and manipulate the microbiome, increased healthcare spending, and a rising consumer preference for products that support digestive health. Together, these factors are propelling the global gut microbiota market toward significant expansion, offering new opportunities for healthcare providers, researchers, and biotech companies to innovate and deliver impactful health solutions.

Growth Influencers:

The rise in digestive disorders such as irritable bowel syndrome (IBS), Crohn's disease, and ulcerative colitis is driving a growing demand for effective management solutions centered on gut microbiota regulation. Scientific studies have demonstrated a strong correlation between the composition of gut microbiota and the prevalence of various gastrointestinal issues. This insight has catalyzed interest in interventions targeting the gut microbiota to potentially prevent, manage, or treat these health conditions.

Probiotics and prebiotics are emerging as promising therapeutic options for these disorders. Probiotics, which are beneficial live bacteria, and prebiotics, which promote the growth of these bacteria, help restore the natural balance of gut microbiota disrupted in individuals suffering from these conditions. Many digestive disorders are linked to an imbalance between the gut microbiota and the immune system, with certain gut bacteria playing a critical role in modulating immune responses within the gut. Addressing this imbalance through targeted microbiota interventions has become a pivotal area of research and product development.

The increasing incidence of digestive disorders has not only heightened public awareness but also enhanced education about the crucial role of gut health in overall well-being. This has spurred interest in products and interventions designed to positively impact gut microbiota.

The global gut microbiota market has seen significant growth, fueled by increased investments from venture capitalists and pharmaceutical companies. From 2015 to 2021, venture capital investment in microbiome-focused companies specializing in human health escalated from $100 million to $400 million annually. Although the number of companies receiving investments grew from twenty-five in 2015 to sixty-six in 2021, there was a decline in 2022, with investments falling by 26% to $321 million across forty-three companies. Despite this recent dip, the last five years have witnessed venture capitalists injecting approximately $1 billion into U.S. companies working on gut microbiome projects, as reported by Crunchbase.

Venture capitalists are increasingly directing substantial funds into companies developing probiotic pills, capsules containing plant extracts, and other nutritional supplements, recognizing these as a potentially profitable market. For example, Seventure Partners, a French venture capital firm, has recently completed the initial funding phase for its second microbiome-focused fund, expected to total €200 million (~US$218 million). This initiative follows the success of the world's first fund dedicated to sectors including nutrition, digital health, and the microbiome.

Additionally, the Israeli startup Biomica raised $20 million in a funding round led by Shanghai Healthcare Capital (SHC), aiming to advance its pipeline of microbiome-based therapeutics. In 2021, EnteroBiotix also secured $21.5 million in a Series A financing round led by Thairm Bio, with contributions from Scottish Enterprise, SIS Ventures, and Kineticos Ventures from the United States, to further develop its drug pipeline targeting the microbiome’s role in health.

Segment Overview:

The Gut Microbiota market is categorized based on Product, Application, Disease Type, End Users and Distribution Channel.

By Product

  • Prebiotics
  • Probiotics
  • Drugs
  • Supplements
  • Others

By Application

  • Digestive Health
  • Immune Health
  • Weight Management
  • Mental Health
  • Cardiovascular Health

By Disease Type

  • Autoimmune Disorder
  • Irritable Bowel Syndrome (IBS)
  • Inflammatory Bowel Disease (IBD)
  • Diabetes
  • Obesity
  • Allergies
  • Others

By End Users

  • Adults
  • Children
  • Elderly

By Distribution Channel

  • Pharmacies and Drugstores
  • Online Retail
  • Health Food Stores
  • Supermarkets and Hypermarkets
  • Specialty Stores
The Gut Microbiota Market, pivotal in addressing a range of digestive disorders, is segmented into Probiotics, Prebiotics, Drugs, Supplements, and Others, with Probiotics leading at a segmental share of 52.51% in 2023. The surge in this segment is primarily due to increased consumer awareness of the critical role a healthy gut microbiome plays in overall well-being, supported by scientific evidence and endorsements from bodies such as the American Gastroenterological Association. Probiotics are recommended for scenarios including the prevention of gut infections during antibiotic use and support for certain conditions in preterm infants and individuals with inflammatory bowel disease, especially pouchitis. The Probiotics segment is projected to grow at the highest CAGR, reflecting a growing recognition of the importance of maintaining a healthy gut microbiome.

In terms of application, the market is categorized into segments including Digestive Health, Immune Health, Weight Management, Mental Health, and Cardiovascular Health. Digestive Health dominates with a highest share of 44.38%, attributed to the fundamental role gut microbiota plays in digestion, energy harvesting, and immune defense, significantly enhancing nutrient and mineral absorption, enzyme, vitamin, and amino acid synthesis, and the production of short-chain fatty acids (SCFAs). This segment is anticipated to grow at a CAGR highlighting the increasing awareness of gut microbiota's impact on overall health.

Based on disease type, the segments include Autoimmune Disorder, Irritable Bowel Syndrome (IBS), Inflammatory Bowel Disease (IBD), Diabetes, Obesity, Allergies, and others. IBS holds the highest market share of 31.43% in 2023, due to its strong association with alterations in gut microbiota. Emerging research underscores the microbiota’s significant influence on the gastrointestinal manifestations of IBS, leading to its projected highest segment CAGR over the forecast period.

In terms of end users, the market segments include Adults, Children, and the Elderly, with the Elderly segment capturing the highest market share of 54.50% in 2023. The focus on the elderly is due to the dynamic changes in gut microbiota composition and function with age, which are linked to various age-related health conditions. This segment is expected to experience the highest CAGR driven by increased recognition of the gut microbiota's role in enhancing health and mitigating age-related issues in the elderly.

Based on the distribution channels, the market is segmented into Pharmacies and Drugstores, Online Retail, Health Food Stores, Supermarkets and Hypermarkets, and Specialty Stores. Pharmacies and Drugstores lead with a share of 40% in 2023, valued for their accessibility and reliability as providers of health-related products and advice. Conversely, Supermarkets and Hypermarkets are predicted to witness the highest CAGR. As major retail venues, they offer a wide range of health and wellness products, significantly contributing to their growth within this distribution channel.

Regional Overview:

Based on Region, the market is divided into North America, Europe, Asia Pacific, Middle East and Africa, and South America.
  • North America
  • The U.S.
  • Canada
  • Mexico
  • Europe
  • Western Europe
  • The UK
  • Germany
  • France
  • Italy
  • Spain
  • Rest of Western Europe
  • Eastern Europe
  • Poland
  • Russia
  • Rest of Eastern Europe
  • Asia Pacific
  • China
  • India
  • Japan
  • Australia & New Zealand
  • South Korea
  • ASEAN
  • Rest of Asia Pacific
  • Middle East & Africa (MEA)
  • Saudi Arabia
  • South Africa
  • UAE
  • Rest of MEA
  • South America
  • Argentina
  • Brazil
  • Rest of South America
The Gut Microbiota Market is strongly led by North America, which boasted the highest regional market share in 2023. This dominance reflects the region's deep-rooted awareness and broad adoption of gut microbiota products. North America's leadership in this market is supported by several critical factors. Notably, the population exhibits a high level of health consciousness with a robust emphasis on preventive healthcare and overall wellness, which aligns well with the benefits offered by gut microbiota products.

The region benefits from a strong healthcare infrastructure, which is complemented by state-of-the-art research facilities. This, along with a proactive stance on integrating innovative health solutions, bolsters its market position. The pharmaceutical and nutraceutical sectors in North America are particularly well-developed, creating an ideal setting for the growth and expansion of the gut microbiota market.

Additionally, the regulatory environment in North America is forward-thinking, actively facilitating the introduction and distribution of new health products. This regulatory support, coupled with increasing consumer awareness about the importance of gut health, continues to drive demand for gut microbiota products. Looking forward, North America is expected to maintain its growth trajectory in the Gut Microbiota Market, with projections indicating the highest Compound Annual Growth Rate (CAGR) of 24.26% during the forecast period. This growth underscores the region's ongoing commitment to fostering innovations that support gut health and wellness..

Competitive Landscape:

The Gut Microbiota market is characterized by a vigorous competitive landscape, with prominent entities like Danone, IFF, Ferring B.V., Nestle and Others at the forefront, collectively accounting for approximately/ More than 44.3% of the overall market share. This competitive milieu is fueled by their intensive efforts in research and development as well as strategic partnerships and collaborations, underscoring their commitment to solidifying market presence and diversifying their offerings. The primary competitive factors include pricing, product caliber, and technological innovation. As the Gut Microbiota industry continues to expand, the competitive fervor among these key players is anticipated to intensify. The impetus for ongoing innovation and alignment with evolving customer preferences and stringent regulations is high. The industry's fluidity anticipates an uptick in novel innovations and strategic growth tactics from these leading corporations, which in turn propels the sector's comprehensive growth and transformation.

Report Insights:

  • The global Gut Microbiota Market was valued at US$ 0.58 billion in 2023 and is projected to grow at a CAGR of 23.80% from 2024 to 2032, reaching US$ 2.94 billion by 2031.
  • Probiotics dominate the market with a 52.51% share in 2023, driven by increasing awareness of gut health benefits.
  • Rising healthcare spending globally supports market growth for gut microbiota products.
  • Key players include Danone, IFF, Ferring B.V., and Nestle, focusing on R&D and strategic partnerships.

Questions to be Answered:

  • What is the estimated growth rate of the Gut Microbiota market?
  • What are the key drivers and potential restraints?
  • Which market segments are expected to witness significant growth?
  • Who are the leading players in the market?

Table of Contents

Chapter 1. Research Framework
1.1. Research Objective
1.2. Product Overview
1.3. Market Segmentation
Chapter 2. Research Methodology
2.1. Qualitative Research
2.1.1. Primary & Secondary Sources
2.2. Quantitative Research
2.2.1. Primary & Secondary Sources
2.3. Breakdown of Primary Research Respondents, By Region
2.4. Assumption for the Study
2.5. Market Size Estimation
2.6. Data Triangulation
Chapter 3. Executive Summary: Global Gut Microbiota Market
Chapter 4. Global Gut Microbiota Market Overview
4.1. Industry Value Chain Analysis
4.1.1. Research & Development
4.1.2. Clinical Trials
4.1.3. Lab Testing
4.1.4. End Users
4.2. Industry Outlook
4.2.1. The Global Prevalence of Functional Gastrointestinal Disorders
4.3. PESTLE Analysis
4.4. Porter's Five Forces Analysis
4.4.1. Bargaining Power of Suppliers
4.4.2. Bargaining Power of Buyers
4.4.3. Threat of Substitutes
4.4.4. Threat of New Entrants
4.4.5. Degree of Competition
4.5. Market Dynamics and Trends
4.5.1. Growth Drivers
4.5.2. Restraints
4.5.3. Challenges
4.5.4. Key Trends
4.6. COVID-19 Impact Assessment on Market Growth Trend
4.7. Market Growth and Outlook
4.7.1. Market Revenue Estimates and Forecast (US$ Mn), 2018-2031
4.7.2. Price Trend Analysis
4.8. Competition Dashboard
4.8.1. Market Concentration Rate
4.8.2. Company Market Share Analysis (Value %), 2022
4.8.3. Competitor Mapping
Chapter 5. Global Gut Microbiota Market Analysis, By Product
5.1. Key Insights
5.2. Market Size and Forecast, 2018-2031 (US$ Mn)
5.2.1. Prebiotics
5.2.2. Probiotics
5.2.3. Drugs
5.2.4. Supplements
5.2.5. Others
Chapter 6. Global Gut Microbiota Market Analysis, By Application
6.1. Key Insights
6.2. Market Size and Forecast, 2018-2031 (US$ Mn)
6.2.1. Digestive Health
6.2.2. Immune Health
6.2.3. Weight Management
6.2.4. Mental Health
6.2.5. Cardiovascular Health
Chapter 7. Global Gut Microbiota Market Analysis, By Disease Type
7.1. Key Insights
7.2. Market Size and Forecast, 2018-2031 (US$ Mn)
7.2.1. Autoimmune Disorder
7.2.2. Irritable Bowel Syndrome (IBS)
7.2.3. Inflammatory Bowel Disease (IBD)
7.2.4. Diabetes
7.2.5. Obesity
7.2.6. Allergies
7.2.7. Others
Chapter 8. Global Gut Microbiota Market Analysis, By End Users
8.1. Key Insights
8.2. Market Size and Forecast, 2018-2031 (US$ Mn)
8.2.1. Adults
8.2.2. Children
8.2.3. Elderly
Chapter 9. Global Gut Microbiota Market Analysis, By Distribution Channel
9.1. Key Insights
9.2. Market Size and Forecast, 2018-2031 (US$ Mn)
9.2.1. Pharmacies and Drugstores
9.2.2. Online Retail
9.2.3. Health Food Stores
9.2.4. Supermarkets and Hypermarkets
9.2.5. Specialty Stores
Chapter 10. Global Gut Microbiota Market Analysis, By Region
10.1. Key Insights
10.2. Market Size and Forecast, 2018-2031 (US$ Mn)
10.2.1. North America
10.2.1.1. The U.S.
10.2.1.2. Canada
10.2.1.3. Mexico
10.2.2. Europe
10.2.2.1. Western Europe
10.2.2.1.1. The UK
10.2.2.1.2. Germany
10.2.2.1.3. France
10.2.2.1.4. Italy
10.2.2.1.5. Spain
10.2.2.1.6. Rest of Western Europe
10.2.2.2. Eastern Europe
10.2.2.2.1. Poland
10.2.2.2.2. Russia
10.2.2.2.3. Rest of Eastern Europe
10.2.3. Asia Pacific
10.2.3.1. China
10.2.3.2. India
10.2.3.3. Japan
10.2.3.4. South Korea
10.2.3.5. Australia & New Zealand
10.2.3.6. ASEAN
10.2.3.7. Rest of Asia Pacific
10.2.4. Middle East & Africa
10.2.4.1. UAE
10.2.4.2. Saudi Arabia
10.2.4.3. South Africa
10.2.4.4. Rest of MEA
10.2.5. South America
10.2.5.1. Argentina
10.2.5.2. Brazil
10.2.5.3. Rest of South America
Chapter 11. North America Gut Microbiota Market Analysis
11.1. Key Insights
11.2. Market Size and Forecast, 2018-2031 (US$ Mn)
11.2.1. By Product
11.2.2. By Application
11.2.3. By Disease Type
11.2.4. By End Users
11.2.5. By Distribution Channel
11.2.6. By Country
Chapter 12. Europe Gut Microbiota Market Analysis
12.1. Key Insights
12.2. Market Size and Forecast, 2018-2031 (US$ Mn)
12.2.1. By Product
12.2.2. By Application
12.2.3. By Disease Type
12.2.4. By End Users
12.2.5. By Distribution Channel
12.2.6. By Country
Chapter 13. Asia Pacific Gut Microbiota Market Analysis
13.1. Key Insights
13.2. Market Size and Forecast, 2018-2031 (US$ Mn)
13.2.1. By Product
13.2.2. By Application
13.2.3. By Disease Type
13.2.4. By End Users
13.2.5. By Distribution Channel
13.2.6. By Country
Chapter 14. Middle East and Africa Gut Microbiota Market Analysis
14.1. Key Insights
14.2. Market Size and Forecast, 2018-2031 (US$ Mn)
14.2.1. By Product
14.2.2. By Application
14.2.3. By Disease Type
14.2.4. By End Users
14.2.5. By Distribution Channel
14.2.6. By Country
Chapter 15. South America Gut Microbiota Market Analysis
15.1. Key Insights
15.2. Market Size and Forecast, 2018-2031 (US$ Mn and Units)
15.2.1. By Product
15.2.2. By Application
15.2.3. By Disease Type
15.2.4. By End Users
15.2.5. By Distribution Channel
15.2.6. By Country
Chapter 16. Company Profile (Company Overview, Financial Matrix, Key Product landscape, Key Personnel, Key Competitors, Contact Address, and Business Strategy Outlook)
16.1. Danone
16.2. International Flavors & Fragrances Inc.
16.3. Enterome
16.4. Ferring Pharmaceuticals
16.5. Nestlé Health Science
16.6. Second Genome, Inc.
16.7. Seed Health
16.8. Seres Therapeutics
16.9. Sun Genomics
16.10. Synlogic, Inc.
16.11. Viome
16.12. Yakult Honsha Co., Ltd.
16.13. Other Prominent Companies

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Danone
  • International Flavors & Fragrances Inc.
  • Enterome
  • Ferring Pharmaceuticals
  • Nestlé Health Science
  • Second Genome, Inc.
  • Seed Health
  • Seres Therapeutics
  • Sun Genomics
  • Synlogic, Inc.
  • Viome
  • Yakult Honsha Co., Ltd.