Bringing together examples that until now were often hidden and widely spread throughout the original literature, this textbook shows how to use the correct reagents, conditions or reaction sequences to have access to all possible stereoisomers when beginning synthesis with only a single starting material.
Adopting a didactic approach, the authors have chosen general and simple examples throughout the book so that these reactions can be transferred easily to other reaction types.
While of major interest to master and PhD students alike, this book is also a source of valuable information for organic chemists in both academia and industry.
Adopting a didactic approach, the authors have chosen general and simple examples throughout the book so that these reactions can be transferred easily to other reaction types.
While of major interest to master and PhD students alike, this book is also a source of valuable information for organic chemists in both academia and industry.
Table of Contents
PrefaceGENERAL METHODS TO DIRECT SELECTIVITY
Chemoselectivity
Regioselectivity
Stereoselectivity
Enantioselectivity
DIRECT SELECTIVITY: ACETYLENES AND ALKENES
Acetylenes
Alkenes
DIRECT SELECTIVITY WITH CARBONYL DERIVATIVES
Carbonyl Compounds as Electrophiles
Conjugate Addition to Carbonyl Compounds
DIRECTED SELECTIVITY WITH CARBONYL DERIVATIVES
Carbonyl Compounds as Electrophiles
Conjugate Addition to Carbonyl Compounds
Enolate Derivatives
Miscellaneous
SELECTIVITY AT SP3 -
CENTERS AND HETEROATOMS
Epoxides
Acetals
Ethers
Alcohols and Phenols
Sulfur Compounds
Amines
Halogen Compounds
Index