+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

Directed Selectivity in Organic Synthesis. A Practical Guide. Edition No. 1

  • Book

  • 368 Pages
  • January 2014
  • John Wiley and Sons Ltd
  • ID: 2542586
Bringing together examples that until now were often hidden and widely spread throughout the original literature, this textbook shows how to use the correct reagents, conditions or reaction sequences to have access to all possible stereoisomers when beginning synthesis with only a single starting material.

Adopting a didactic approach, the authors have chosen general and simple examples throughout the book so that these reactions can be transferred easily to other reaction types.

While of major interest to master and PhD students alike, this book is also a source of valuable information for organic chemists in both academia and industry.

Table of Contents

Preface

GENERAL METHODS TO DIRECT SELECTIVITY
Chemoselectivity
Regioselectivity
Stereoselectivity
Enantioselectivity

DIRECT SELECTIVITY: ACETYLENES AND ALKENES
Acetylenes
Alkenes

DIRECT SELECTIVITY WITH CARBONYL DERIVATIVES
Carbonyl Compounds as Electrophiles
Conjugate Addition to Carbonyl Compounds

DIRECTED SELECTIVITY WITH CARBONYL DERIVATIVES
Carbonyl Compounds as Electrophiles
Conjugate Addition to Carbonyl Compounds
Enolate Derivatives
Miscellaneous

SELECTIVITY AT SP3 -
CENTERS AND HETEROATOMS
Epoxides
Acetals
Ethers
Alcohols and Phenols
Sulfur Compounds
Amines
Halogen Compounds

Index

Authors

Tanja Gaich Leibniz University of Hannover, Institute of Organic Chemistry. Ekkehard Winterfeldt Department of Organic Chemistry, University of Hannover, Hannover, Germany.